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Head Trauma

Nanoparticle encapsulated core-shell hydrogel for on-site BMSCs delivery protects from iron overload and enhances functional recovery.

Jan 24, 2020

The local microenvironment may influence the success of stem cell therapy. Iron overload occurs in many hemorrhagic injuries due to hemolysis and hemoglobin degradation, which not only mediates local ...

No Clinical Predictors of Postconcussion Musculoskeletal Injury in College Athletes.

Jan 24, 2020

To identify clinical predictors of post-concussion subsequent musculoskeletal (MSK) injuries.We recruited 66 NCAA intercollegiate student-athletes with a diagnosed concussion as well as 36 NCAA studen...

Worse Than Death: Survey of Public Perceptions of Disability Outcomes After Hypothetical Traumatic Brain Injury.

Jan 24, 2020

The aim of this study was to determine the health utility states of the most commonly used traumatic brain injury (TBI) clinical trial endpoint, the Extended Glasgow Outcome Scale (GOSE).Health utilit...

Impact of PTEN/SOCS3 deletion on amelioration of dendritic shrinkage of retinal ganglion cells after optic nerve injury.

Jan 24, 2020

Retinal ganglion cell (RGC) degeneration, leading to irreversible blindness in chronic optic neuropathies such as glaucoma, begins with dendritic shrinkage followed by axon degeneration. Although limi...

A management algorithm for adult patients with both brain oxygen and intracranial pressure monitoring: the Seattle International Severe Traumatic Brain Injury Consensus Conference (SIBICC).

Jan 23, 2020

Current guidelines for the treatment of adult severe traumatic brain injury (sTBI) consist of high-quality evidence reports, but they are no longer accompanied by management protocols, as these requir...

Mild and Moderate Traumatic Brain Injury and Gender-Based Critical Care Outcomes.

Jan 23, 2020

Traumatic brain injury (TBI) is a major contributor to death and complications. Previous studies have identified gender disparities among trauma patients. This study aims to examine the association be...

A Three-Dimensional Statistical Volume Element for Histology Informed Micromechanical Modeling of Brain White Matter.

Jan 23, 2020

This study presents a novel statistical volume element (SVE) for micromechanical modeling of the white matter structures, with histology-informed randomized distribution of axonal tracts within the ex...