Jan 24, 2022

This phase I trial (NCT01912625) evaluated the safety and pharmacokinetics of definitive concurrent chemoradiotherapy (cCRT) and the radiosensitizer trametinib (MEK1/2 inhibitor) for KRAS-mutated nonm...

Jan 24, 2022

Nurses have a key role in the early assessment and management of sepsis, which is crucial for optimal quality of care and better patient outcomes. However, sepsis in critical care patients is underrec...

Jan 10, 2022

To report maternal outcomes in a cohort of women who received autotransfusion of vaginally shed blood and to describe the feasibility of blood collection and cell salvage processing at the time of vag...

Dec 20, 2021

Sepsis is a predominant reason for the growing morbidity and mortality in the world. The role of circular RNAs (CircRNAs) is actively researched in sepsis. In this study, we attempt to find out the ef...

Dec 10, 2021

According to recent estimates, sepsis is attributable to approximately one in three hospital deaths in the United States. “Sepsis is a common and deadly condition that can be difficult to identify i...

Dec 06, 2021

It has been reported that there are differences in the care given within the intensive care unit (ICU) between men and women. The aim of this study is to investigate if any differences still exist bet...

Nov 29, 2021

We report the results of the surgical treatment of anal fissures complicated by abscess or fistula and formulate hypotheses about their nature. Among patients operated between 2012 and 2020 for anal f...

Nov 29, 2021

Studies of sepsis evaluating sex- and race-related disparities in treatment and outcome have been limited by using administrative databases, which may not adequately capture sepsis diagnosis, used lim...

Nov 15, 2021

This study investigates the synergistic effect of TGF-β1 and Nrp-1 on CD4 CD25 T ' stabilization, and the associated pathways of signal transduction, in vitro models in the presence of LPS.Spleen CD4...

Nov 11, 2021

“Growing evidence indicates that survivors of sepsis face multiple health challenges after their initial hospitalization, along with high rates of healthcare utilization and mortality,” explains S...

Nov 08, 2021

Polymicrobial bloodstream infections (pBSI) occurring in hematological patients are still poorly understood, and specific information are very limited.In this epidemiologic survey, we describe clinica...

Nov 08, 2021

Several lakes in southwestern Nova Scotia, Canada have experienced reoccurring algal blooms and possess concentrations of phosphorus (P) that are in the eutrophic to hypereutrophic range (>35 μg/L...

Nov 03, 2021

Early antibiotic therapy has been shown to improve outcomes in sepsis, but patients often present with vague symptoms, making it difficult to recognize the condition early. Treatment delays can occur ...

Nov 01, 2021

The presence of pharmaceuticals and personal care products (PPCPs) in the environment is primarily the result of discharge of waste, including from onsite wastewater treatment systems (OWTSs) which ar...

Oct 18, 2021

The enteroinsular axis (EIA) is an energy regulatory system that modulates insulin secretion through the release of enteroendocrine factors (incretins). Despite the importance of energy homeostasis in...

Oct 11, 2021

Sepsis is one of the leading causes of morbidity and mortality in the pediatric population worldwide. This study aimed to establish a correlation between platelet count and outcomes of severe sepsis/s...

Oct 04, 2021

The purpose of this study was to evaluate survival and freedom from reinfection of patients with infected native aortic aneurysms (INAA) managed with in situ revascularization (ISR), either with open ...

Sep 27, 2021

Oxidative stress and inflammatory responses play an important role in acute lung injury (ALI). Although minocycline (MINO) has anti-inflammatory effects and is a promising candidate in treating inflam...

Sep 21, 2021

Sepsis is the most commonly identified risk factor for acute kidney injury (AKI), according to published research. “While we know that sepsis-associated acute kidney injury (SA-AKI) has significant...

Sep 20, 2021

Sepsis is a serious organ dysfunction leading to endothelial damage in critical patients. Physiologically, there is an augment of vascular diameter in response to increased vascular blood flow and she...