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Sepsis

Race and sex based disparities in sepsis.

Nov 29, 2021

Studies of sepsis evaluating sex- and race-related disparities in treatment and outcome have been limited by using administrative databases, which may not adequately capture sepsis diagnosis, used lim...

The contribution of neuropilin-1 in the stability of CD4 CD25 regulatory T cells through the TGF-β1/Smads signaling pathway in the presence of lipopolysaccharides.

Nov 15, 2021

This study investigates the synergistic effect of TGF-β1 and Nrp-1 on CD4 CD25 T ' stabilization, and the associated pathways of signal transduction, in vitro models in the presence of LPS.Spleen CD4...

Deficits Found in Identification of Patient Goals Post-Sepsis Hospitalization

Nov 11, 2021

“Growing evidence indicates that survivors of sepsis face multiple health challenges after their initial hospitalization, along with high rates of healthcare utilization and mortality,” explains S...

Clinical characteristics and outcome of 125 polymicrobial bloodstream infections in hematological patients: an 11-year epidemiologic survey.

Nov 08, 2021

Polymicrobial bloodstream infections (pBSI) occurring in hematological patients are still poorly understood, and specific information are very limited.In this epidemiologic survey, we describe clinica...

Application of phosphorus loading models to understand drivers of eutrophication in a complex rural lake-watershed system.

Nov 08, 2021

Several lakes in southwestern Nova Scotia, Canada have experienced reoccurring algal blooms and possess concentrations of phosphorus (P) that are in the eutrophic to hypereutrophic range (>35 μg/L...

Sepsis: Assessing a Biomarker & EMR‐Based Machine Learning Algorithm

Nov 03, 2021

Early antibiotic therapy has been shown to improve outcomes in sepsis, but patients often present with vague symptoms, making it difficult to recognize the condition early. Treatment delays can occur ...

Occurrence and removal of PPCPs from on-site wastewater using nitrogen removing biofilters.

Nov 01, 2021

The presence of pharmaceuticals and personal care products (PPCPs) in the environment is primarily the result of discharge of waste, including from onsite wastewater treatment systems (OWTSs) which ar...

The enteroinsular axis during hospitalization in newborn foals.

Oct 18, 2021

The enteroinsular axis (EIA) is an energy regulatory system that modulates insulin secretion through the release of enteroendocrine factors (incretins). Despite the importance of energy homeostasis in...

Association between platelet count and multiorgan dysfunction and outcomes in patients with sepsis in the pediatric intensive care unit in Saudi Arabia.

Oct 11, 2021

Sepsis is one of the leading causes of morbidity and mortality in the pediatric population worldwide. This study aimed to establish a correlation between platelet count and outcomes of severe sepsis/s...

Fifteen years single-center experience with In Situ Reconstruction for Infected Native Aortic Aneurysms.

Oct 04, 2021

The purpose of this study was to evaluate survival and freedom from reinfection of patients with infected native aortic aneurysms (INAA) managed with in situ revascularization (ISR), either with open ...

Minocycline attenuates oxidative and inflammatory injury in a intestinal perforation induced septic lung injury model via down-regulating lncRNA MALAT1 expression.

Sep 27, 2021

Oxidative stress and inflammatory responses play an important role in acute lung injury (ALI). Although minocycline (MINO) has anti-inflammatory effects and is a promising candidate in treating inflam...

Predicting Long-Term Complications After Sepsis-Associated Acute Kidney Disease

Sep 21, 2021

Sepsis is the most commonly identified risk factor for acute kidney injury (AKI), according to published research. “While we know that sepsis-associated acute kidney injury (SA-AKI) has significant...

Patterns of vascular response immediately after passive mobilization in patients with sepsis: an observational transversal study.

Sep 20, 2021

Sepsis is a serious organ dysfunction leading to endothelial damage in critical patients. Physiologically, there is an augment of vascular diameter in response to increased vascular blood flow and she...

Very preterm infants admitted to a tertiary neonatal unit in central Vietnam showed poor postnatal growth.

Sep 20, 2021

We aimed to evaluate the postnatal growth of very preterm infants.This was a cross-sectional observational study of neonates born before 32 weeks of gestation and admitted to the neonatal unit at Da N...

Cardiac steroid ouabain transcriptionally increases human leukocyte antigen DR expression on monocytes.

Sep 13, 2021

Sepsis is a life-threatening disease characterized by acute multiple organ dysfunction and immunosuppression that is also called as immunoparalysis. Increasing evidence suggests that immunoparalysis l...

Interleukin-35 inhibits lipopolysaccharide-induced endothelial cell activation by downregulating inflammation and apoptosis.

Sep 13, 2021

Inflammation is an essential factor contributing to sepsis-induced endothelial cell (EC) activation. Interleukin-35 (IL-35) is an anti-inflammatory/immunosuppressive cytokine that exerts protective ef...

Amyand's hernia a case report.

Sep 13, 2021

Amyand's hernia (AH) is a form of inguinal hernia which is consider as very rare and this type of hernia occurred up to 1% of all inguinal hernia cases. In this type of inguinal hernia, the content of...

Risk factors of surgical mortality in patients with Clostridium difficile colitis. A novel scoring system.

Sep 06, 2021

The purpose of the study is to identify the risk factors of mortality and develop a risk scoring system in patients who underwent colectomy due to Clostridium difficile colitis (CD-C).Patient informat...

Combination of hepcidin with neutrophil gelatinase-associated lipocalin for prediction of the development of sepsis-induced acute kidney injury.

Sep 06, 2021

The early prediction of the development of acute kidney injury (AKI) in critically ill patients with sepsis would facilitate early effective intervention. Recently, interest has focused on the biomark...

Diabetes & Infection-Related Hospitalization

Sep 01, 2021

“Diabetes is widely thought to increase susceptibility to infection by impairing neutrophil functioning, antioxidant systems, and humoral immune response,” explains Michael Fang, PhD. “Consisten...