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Stroke

#VisualAbstract: Thrombectomy alone is inferior to thrombectomy plus alteplase for acute ischemic stroke

Aug 05, 2022

1. Fewer patients in the thrombectomy group achieved an MRS score of 0-2 at 90 days compared to thrombectomy with alteplase (57% vs. 65%). 2. Thrombectomy with alteplase resulted in significant...

Adding ‘Cancer’ to Risk Calculator May Help Predict Stroke in AF

Jul 14, 2022

Adding “cancer” to the atrial fibrillation prediction model improved the predictability of assessing the probability of stroke-free survival in patients. Several risk assessment tools have ...

Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia-reperfusion injure by restoring CPT1A mediated fatty acid oxidation.

May 09, 2022

Renal fibrosis is a common pathological process of chronic kidney diseases induced by multiple factors. Hypoxic pretreatment of mesenchymal stem cells can enhance the efficacy of secreted extracellula...

Early MRI diagnosis of Sturge Weber Syndrome type 1 in infants.

Apr 25, 2022

Patients with Sturge-Weber syndrome type 1 (SWS1) have a port-wine birthmark (PWB) as cutaneous hallmark. Up to 35% of neonates with a high risk PWB develop SWS1. Clinical manifestations are severe an...

Colocolic intussusception secondary to colonic adenocarcinoma with impending caecal perforation in an elderly patient: A rare case report.

Apr 25, 2022

Intussusception is a surgical emergency in which a part of the intestine slides into the distal adjacent part. Adult colocolic intussusception secondary to a tumoral process is a rare but serious clin...

Peripapillary Microvascular and Structural Parameters in Atrophic Nonarteritic Anterior Ischemic Optic Neuropathy and Their Unaffected Fellow Eyes.

Apr 18, 2022

This cross-sectional study aimed to evaluate the peripapillary vessel density (VD), peripapillary retinal nerve fiber layer (RNFL) thickness values of eyes with atrophic nonarteritic anterior ischemic...

MS or not MS: T2-weighted imaging (T2WI)-based radiomic findings distinguish MS from its mimics.

Apr 11, 2022

Ischemic vasculopathy, particularly small-vessel disease, may mimic multiple sclerosis (MS) located in the periventricular or subcortical region on magnetic resonance (MR) examinations and should be i...

Therapeutic effect of quercetin polymeric nanoparticles on ischemia/reperfusion-induced acute kidney injury in mice.

Apr 11, 2022

Acute kidney injury (AKI) is known as a sudden episode of kidney injury, which happens suddenly within a few hours or a few days. Quercetin (3,3',4',5,7-pentahydroxyflavone) is a flavonoid found in pl...

Higher serum occludin after successful reperfusion Is associated with early neurological deterioration.

Mar 28, 2022

Early neurological deterioration (END) is an important factor that affects prognosis in patients with acute ischemic stroke. We explored the relationship between serum occludin levels after successful...

Implication of IGF1R signaling in the protective effect of Astragaloside IV on ischemia and reperfusion-induced cardiac microvascular endothelial hyperpermeability.

Mar 28, 2022

Myocardial ischemia-reperfusion (I/R) causes damage to coronary capillary endothelial barrier and microvascular leakage (MVL), aggravating tissue injury and heart dysfunction. However, the effective s...

Progressive Small-Vessel Strokes Following Antiretroviral Therapy in a Patient with Acquired Immunodeficiency Syndrome.

Mar 07, 2022

We report a case of a 59-year-old man with human immunodeficiency virus (HIV)/ acquired immunodeficiency syndrome (AIDS) who developed multiple small-vessel strokes during the immune reconstitution ph...

Association of hypoxic ischemic brain injury on early CT after out of hospital cardiac arrest with neurologic outcome.

Feb 28, 2022

This study aimed to describe the prevalence of hypoxic-ischemic brain injury (HIBI) on head CT (HCT) obtained within two hours of return of spontaneous circulation (ROSC) care in the Emergency Departm...

Effects of azumolene on arrhythmia substrate in a model of recurrent long-duration ventricular fibrillation.

Feb 28, 2022

Proarrhythmic risk of conventional anti-arrhythmic agents is linked to unintended modulation of membrane voltage dynamics. We have demonstrated that the anti-fibrillatory effect of azumolene is mediat...

Evaluating gastric remnant ischemia by indocyanine green fluorescence-guided surgery after distal gastrectomy in a patient with prior Nissen fundoplication: A case report.

Feb 21, 2022

Recent studies showed that intraoperative indocyanine green (ICG) fluorescence imaging-guided surgery helped evaluate organ perfusion. Whereas whether the gastric remnant can be preserved after distal...

Posterior Circulation Alberta Stroke Program Early Computed Tomography Score (pc-ASPECT) for the Evaluation of Cerebellar Infarcts.

Jan 24, 2022

Patients with cerebellar ischemic stroke may be misdiagnosed and may exhibit a delayed time to acute stroke treatment compared with patients with anterior circulation ischemic stroke. The posterior ci...

Major Neurological Deficit Following Neck Hyperextension During Dental Treatment: Report of 2 Cases and Review of the Literature.

Jan 24, 2022

Medical literature has long reported the disastrous effects of neck hyperextension on posterior cerebral circulation. Hairdresser-related ischemic cerebrovascular event, also called beauty parlor synd...

Analysis of stroke care among 2019-2020 national emergency medical services information system encounters.

Jan 10, 2022

Emergency Medicine Service (EMS) providers play a pivotal role in early identification and initiation of treatment for stroke. The objective of this study is to characterize nationwide EMS practices f...

Risks of Cardiovascular Events in Patients with Inflammatory Bowel Disease in China: A Retrospective Multicenter Cohort Study.

Jan 03, 2022

Inflammatory bowel disease (IBD) is a complex chronic disorder characterized by systemic inflammation, which may cause abnormal state of coagulation, resulting in cardiac events. This study aimed to i...

Gene polymorphism in tissue epidermal growth factor receptor (EGFR) influences clinical and histological vulnerability of carotid plaques.

Dec 27, 2021

Different models have been proposed for the prediction of the risk/benefit ratio of surgery in patients with carotid atheromasic disease, mainly based on clinical patients' characteristics and risk fa...

The deleterious effect of crossfostering in rat pups on hypoxic-ischemic injury tolerance and hypothermic neuroprotection.

Dec 20, 2021

We study the effect of hypothermia (HT) following hypoxic-ischemic (HI) brain injury in postnatal day 7 (P7) rats. In 2015, new European Union animal transport regulations prompted a change in practic...