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Stroke

Effects of transportation noise and particulate matter on the cardiovascular system: What is the new evidence?

Mar 04, 2020

Several decades of research provides compelling evidence that exposure to air pollution causes various diseases. Time series studies in Europe and the USA examined the short term effects on mortality ...

Iron Sucrose as MRI Contrast Agent in Ischemic Stroke Model.

Mar 02, 2020

Despite the growing concern about the safety of gadolinium-based contrast agents (GBCAs), they are still the most commonly used. Ferumoxytol, as an off-label alternative MRI contrast agent, cannot be ...

Musk ketone induces neural stem cell proliferation and differentiation in cerebral ischemia via activation of the PI3K/Akt signaling pathway.

Mar 02, 2020

Traditional Chinese medicine has been reported to influence the proliferation and differentiation of neural stem cells (NSCs) that may be protective against nervous system diseases. Recent evidence in...

Neuroprotective effects of saffron on the late cerebral ischemia injury through inhibiting astrogliosis and glial scar formation in rats.

Mar 02, 2020

This study is to explore the neuroprotective effects and involved glial scar of saffron (Crocus sativus L.) on the late cerebral ischemia in rats. Focal cerebral ischemia was induced by middle cerebra...

The effect of the economic collapse in Iceland on the probability of cardiovascular events.

Feb 28, 2020

After several years of a booming economy in Iceland, the economic bubble burst in 2008 and affected most Icelanders in one way or another. We explore whether the economic collapse in 2008 and subseque...

Susceptibility of rat steatotic liver to ischemia-reperfusion is treatable with liver-selective matrix metalloproteinase inhibition.

Feb 18, 2020

This study examined whether enhanced susceptibility of steatotic liver to I/R injury is due to impaired recruitment of bone marrow (BM) progenitors of LSECs (also called sprocs) with diminished repair...

Hypoxic-ischemic-related cerebrovascular changes and potential therapeutic strategies in the neonatal brain.

Feb 18, 2020

Perinatal hypoxic-ischemic (HI)-related brain injury is an important cause of morbidity and long-standing disability in newborns. The only currently approved therapeutic strategy available to reduce b...

Mitochondrial division inhibitor 1 disrupts oligodendrocyte Ca homeostasis and mitochondrial function.

Feb 18, 2020

Mitochondrial fission mediated by cytosolic dynamin related protein 1 (Drp1) is essential for mitochondrial quality control but may contribute to apoptosis as well. Blockade of Drp1 with mitochondrial...

Inhibition of MiR-122 Decreases Cerebral Ischemia-reperfusion Injury by Upregulating DJ-1-Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN)/Phosphonosinol-3 Kinase (PI3K)/AKT.

Feb 18, 2020

BACKGROUND Ischemia-reperfusion injury is caused by a blood reperfusion injury in ischemic brain tissue, and usually occurs in the treatment stage of ischemic disease, which can aggravate brain tissue...

Smoking tied to worse outcomes after a stroke

Jan 14, 2020

By Lisa Rapaport People who smoke or have recently quit have higher odds of being severely impaired after a stroke than their counterparts who never smoked, a new study su...