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Stroke

1-trifluoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) Urea Exerts Neuro-Protective Effects Against Ischemic Injury via Suppressing JNK/p38 MAPK-Mediated Mitochondrial Apoptosis Pathway.

Jul 05, 2021

1-trifluoromethoxyphenyl-3-(1- propionylpiperidin-4-yl) urea (TPPU) is a novel soluble epoxide hydrolase inhibitor which can protect against cerebral ischemic injury in middle cerebral artery occlusio...

Low Birth Weight as an Early Life Risk Factor for Adult Stroke Among Men.

Jul 01, 2021

To evaluate the association between birth weight and the risk of adult stroke in men, independent of body mass index (BMI) at young adult age.We included 35,659 men born 1945-61 from the BMI Epidemiol...

Complicated Littre's umbilical hernia with normal Meckel's diverticulum: A case report and review of the literature.

Jul 01, 2021

A Littre's hernia (LH) is defined by the presence of Meckel's diverticulum (MD) in any kind of hernia sac. Preoperative diagnosis of LH is a challenge because of its rarity and the absence of specific...

Trillium tschonoskii rhizomes' saponins induces oligodendrogenesis and axonal reorganization for ischemic stroke recovery in rats.

Jun 28, 2021

Trillium tschonoskii Maxim. is one of traditional Chinese medical herbs that has been utilized to treat brain damages and cephalalgia. The neuroprotective effect of total saponins from Trillium tschon...

IL-38 as an early predictor of the ischemic stroke prognosis.

Jun 24, 2021

Ischemic stroke is caused by a sudden neurological defect following a vascular occlusion and elicits a local and systemic inflammation in brain tissue. Interleukin-38 is an anti-inflammatory cytokine ...

Indoleamine-2,3-Dioxygenase Activates Wnt/β-Catenin Inducing Kidney Fibrosis after Acute Kidney Injury.

Jun 17, 2021

As disorder of tryptophan metabolism is common in CKD, the rate-limiting enzyme of tryptophan, indoleamine-2,3-dioxygenase (IDO), has been reported to be involved in CKD, while the accurate mechanism ...

Glucose metabolic crosstalk and regulation in brain function and diseases.

Jun 14, 2021

Brain glucose metabolism, including glycolysis, the pentose phosphate pathway, and glycogen turnover, produces ATP for energetic support and provides the precursors for the synthesis of biological mac...

Does Severity of Brain Injury on Magnetic Resonance Imaging Predict Short-Term Outcome in Neonates Who Received Therapeutic Hypothermia?

Jun 10, 2021

 The National Institute of Child Health and Human Development (NICHD) magnetic resonance imaging (MRI) pattern of brain injury is a known biomarker of childhood outcome following therapeutic hypothe...

COVID-19: Autopsy findings in six patients between 26 and 46 years of age.

Jun 07, 2021

Studies on the coronavirus disease 2019 (COVID-19) usually focus on middle aged and older adults. However, younger patients may present with severe COVID-19 and potentially fatal outcomes. For optimiz...

Association of Initial Potassium Levels with the Type of Stroke in the Emergency Department.

Jun 03, 2021

Serum potassium levels are considered as a marker of cerebrovascular emergencies but there is less clarity on the association between initial serum potassium levels recorded on patient's arrival at th...

Emerging Concepts in Vascular Dementia: A Review.

Jun 03, 2021

Vascular dementia (VaD) is the second most common cause of dementia and a major health concern worldwide. A comprehensive review on VaD is warranted for better understanding and guidance for the pract...

Diagnosis and management of acute lower gastrointestinal bleeding: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Jun 03, 2021

1: ESGE recommends that the initial assessment of patients presenting with acute lower gastrointestinal bleeding should include: a history of co-morbidities and medications that promote bleeding; hemo...

THE EFFECT OF CARBON MONOXIDE RELEASING MOLECULE-2 ON HEALING OF ISCHEMIC COLON ANASTOMOSIS IN RATS.

May 31, 2021

Ischemia on the colon wall negatively affects healing of anastomosis. We were aimed to evaluate the effects of Carbon Monoxide Releasing Molecule-2 (CORM-2) on the healing of anastomosis in a rat mode...

Outcomes of Homeless Ischemic Stroke Patients Receiving Intravenous Thrombolysis in the United States.

May 27, 2021

Morbidity and mortality among homeless people with cardiovascular diseases and stroke in the United States is high. Adverse outcomes within the homeless population may be the result of seeking care to...

Superb Microvascular Imaging Ultrasound for Cervical Carotid Artery Stenosis for Prediction of the Development of Microembolic Signals on Transcranial Doppler during Carotid Exposure in Endarterectomy.

May 27, 2021

During exposure of the carotid arteries, embolism from the surgical site is recognized as a primary cause of neurological deficits or new cerebral ischemic lesions following carotid endarterectomy (CE...

Hepatic portal vein gas detected by point of care ultrasound.

May 24, 2021

Portal venous gas is a rare finding in adults and is typically associated with underlying intestinal ischemia. Portal venous gas can be detected by a bedside point of care ultrasound (POCUS) examinati...

Predicting experimental success: A retrospective case-control study using the rat intraluminal thread model of stroke.

May 20, 2021

The poor translational success rate of preclinical stroke research may partly be due to inaccurate modelling of the disease. We provide data on transient middle cerebral artery occlusion (tMCAO) exper...

Functional Imaging in Wounds: Imaging Modalities of Today and Tomorrow.

May 20, 2021

Wound care is a multidisciplinary field with significant economic burden to our healthcare system. Not only does wound care cost the US healthcare system $20 billion annually, but wounds also remarkab...

Protective Effect of Hydrogen Gas on Mice Hind Limb Ischemia-Reperfusion Injury.

May 17, 2021

The aim of this study was to investigate the mechanism of hydrogen gas on hind limb IR injury.Male C57BL/6 mice were randomly divided into three groups: sham group (Sham), ischemia-reperfusion group (...

Effects of Tourniquet Application on Faster Recovery after Surgery and Ischemia-Reperfusion Post-Total Knee Arthroplasty, Cementation through Closure versus Full-Course and Nontourniquet Group.

May 17, 2021

Pneumatic tourniquets are used in total knee arthroplasty (TKA) for surgical field visualization and improved cementation; however, their use is controversial. This study aimed to assess the effects o...