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Endocrinology General

Risks & Burdens of Incident Diabetes in Long COVID

May 26, 2022

For a study, researchers sought to determine the post-acute risk and burden of incident diabetes in people who survived the first 30 days after contracting SARS-CoV-2. They used the US Department of V...

Sleep Disturbance, Energy Intake Changes & Body Composition During Weight Loss

May 26, 2022

For a study, researchers included 810 overweight or obese individuals with baseline sleep disturbance assessments who were randomly assigned one of four diets varying in macronutrient composition to e...

Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity

May 26, 2022

Chronic liver inflammation causes insulin resistance in various tissues, including skeletal muscle (SM); nevertheless, the underlying processes are largely unclear. The expression of hepatokine endop...

Endogenous Insulin-Regulated TBC1D4 Interactome in Human Skeletal Muscle

May 26, 2022

Muscle glucose absorption driven by insulin is an important step in glycemic regulation. This process is dependent on the redistribution of glucose transporters to the surface membrane, which is regul...

Alteration of the Individual Metabolic Network of the Brain in T2DM Elderly Patients

May 26, 2022

For a study, researchers sought to determine how aging and type 2 diabetic Mellitus (T2DM) interacted with brain glucose metabolism, individual metabolic connections, and network dynamics. About 83 pa...

Circulating Metabolites: All-Cause Mortality in Type 2 Diabetes

May 26, 2022

Type 2 diabetes increases the risk of death. To address this problem, biomarkers of novel pathogenic pathways capable of identifying high-risk patients must be identified. For a study, researchers ex...

Genetic Loci Associated With Fat Cell Number & Overlap With Type 2 Diabetes

May 26, 2022

Body fat and type 2 diabetes risk are determined by interindividual changes in creating new fat cells. For a study, researchers conducted a genome-wide association study (GWAS) of fat cell numbers (n=...

Serum Metabolomics of Incident Diabetes & Glycemic Changes

May 24, 2022

The metabolomic markers of incident diabetes in the Hispanic/Latino population of the United States, a group with a high diabetes burden, remained largely unknown. In a subsample (n=2,010) of the His...

Genomics & Proteomics to Identify Protein Biomarkers for Adult & Youth-Onset T2D

May 24, 2022

Type 2 diabetes is becoming more common in both adults and children. Therefore, identifying biomarkers for juvenile and adult-onset type 2 diabetes was critical to creating screening tools or therapeu...

Blood Neuroexosomal Mitochondrial Proteins Predict Alzheimer Disease in Diabetes

May 24, 2022

There was mounting evidence that mitochondrial dysfunction is linked to diabetes's role in Alzheimer's disease (AD) development. Neuronal mitochondrial proteins are discovered at quantities similar to...

Renox, NOX5 Promotes Renal Inflammation & Fibrosis in Diabetes

May 24, 2022

Excessive generation of renal reactive oxygen species (ROS) contributes significantly to diabetic kidney damage (DKD). For a study, researchers provided crucial data indicating that the pro-oxidant en...

Rate-Dependent Depression: Treating Diabetic Peripheral Neuropathy (DPN)

May 24, 2022

The rate-dependent depression (RDD) of the Hoffmann (H) wave was examined as a predictor of therapy success in individuals with painful diabetic peripheral neuropathy (DPN).  About 73 healthy patient...

Islet Autoimmunity Associated With Diminished β-Cell Function in Type 2 Diabetes Patients

May 24, 2022

Autoimmunity to the islets may lead to -cell dysfunction in type 2 diabetes (T2D). However, its frequency and clinical relevance have yet to be identified. For a study, researchers assessed the incide...

Cold-Stimulated Supraclavicular BAT Activity in Young Boys With Obesity

May 24, 2022

Obesity in children is becoming a global issue. Lower cold-induced brown adipose tissue (BAT) activity had been associated with obesity and metabolic dysfunction in adults, but the same cannot be said...

Time-restricted Eating (TRE): Prevention & Management of Metabolic Diseases

May 24, 2022

Time-restricted feeding (TRF) and time-restricted eating (TRE) are two developing behavioral intervention approaches based on a better knowledge of circadian rhythms in physiology and metabolism. With...

Review of Optimal Thyroid Hormone Replacement

May 24, 2022

Hypothyroidism is a common endocrinopathy, and levothyroxine is commonly used to treat it. Despite agreement on the basic concepts of starting and modifying levothyroxine, there are many subtleties an...

Myostatin/Activin Receptor Ligands & the Attenuating Drugs

May 24, 2022

Muscle wasting disease symptoms are among the most incapacitating and frequently fatal non-communicable illness conditions. Muscle wasting is linked to various neuromuscular illnesses and myopathies, ...

Arcuate Nucleus-Dependent Regulation of Metabolism—Pathways to Obesity & Diabetes Mellitus

May 24, 2022

The central nervous system (CNS) combines information from afferent neurons, circulating hormones, and ingested nutrients to regulate the actions of the neuroendocrine and autonomic nervous systems to...

Secondary Osteoporosis: Chronic Disease

May 24, 2022

Osteoporosis is a worldwide public health issue, with fractures causing major morbidity and mortality. However, postmenopausal osteoporosis was the most prevalent; secondary osteoporosis affected up t...

Personalized Management of Pheochromocytoma & Paraganglioma

May 24, 2022

Pheochromocytomas/paragangliomas have a distinct molecular landscape that allows them to be classified into clusters based on underlying genetic changes. Pheochromocytomas/paragangliomas have the grea...