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Endocrinology General

Extracellular Vesicles (EV) & Their Roles in Endocrinology

May 24, 2022

In a study, researchers determined that over the last decade, there has been a significant interest in explaining the biological significance of extracellular vesicles (EVs), notably their hormone-lik...

Thyroid Function in Lactating Women & Infants: Iodine's Role

May 24, 2022

Iodine is a micronutrient required for thyroid hormone synthesis, which regulates metabolism, growth, and development. Thyroid hormone production can be altered by iodine deficit or excess. The degree...

Noninvasive Approaches to Obesity Treatment: From Pharmacotherapy to Gene Therapy

May 24, 2022

Recent discoveries on the underlying pathophysiologic processes of obesity have resulted in the identification of various viable pharmacological targets and innovative treatment techniques for address...

Mitochondrial Disease: Endocrine Manifestations & Developments

May 24, 2022

Mitochondrial illnesses are a set of frequent hereditary diseases that cause oxidative phosphorylation to be disrupted. Endocrine signs of mitochondrial illness are seen in certain individuals, with d...

The Multifaceted Biology of PCSK9

May 24, 2022

The discovery of PCSK9, its structure-function features, and it's currently known and hypothesized new biological roles were discussed by researchers for a study. The main crucial function of PCSK9 in...

Understanding the barriers to, and facilitators of, ovarian toxicity assessment in breast cancer clinical trials.

May 23, 2022

Detailed toxicity data are routinely collected in breast cancer (BC) clinical trials. However, ovarian toxicity is infrequently assessed, despite the adverse impacts on fertility and long-term health ...

Sex Differences in the Immune System in Relation to Hypertension and Vascular Disease.

May 23, 2022

Hypertension is the leading risk factor for cardiovascular disease and mortality worldwide. Despite intensive research into the mechanisms underlying the development of hypertension, it remains diffic...

Betaine attenuate chronic restraint stress-induced changes in testicular damage and oxidative stress in male mice.

May 23, 2022

Male fertility and sperm quality are negatively affected by psychological stress. Chronic restraint stress (CRS) is a common psychological stress that has a negative effect on sperm. Betaine (BET), an...

Attitudes toward posthumous assisted reproduction in China: a multi-dimensional survey.

May 23, 2022

Professional legislation and ethics guidelines for posthumous assisted reproduction (PAR) are lacking in China. This study aims to measure the attitudes of the general public, IVF couples, and assiste...

Type 1 Diabetes in Laos, 2016 - 2021.

May 23, 2022

Before 2016, no child was known to survive type 1 diabetes (T1D) in Laos, a lower-middle income country (LMIC) in South-east Asia. In partnership with the Laos government, a non-government organizatio...

The Benefits of Higher Protein Intake During Caloric Restriction

May 20, 2022

While patients who are dieting to reduce body weight might try to maintain protein intake, protein levels often fall below what is recommended. Although previous studies have reported on the ef...

Explore Weight Bias of Professionals in the Field of Obesity Using a Mobile IAT

May 20, 2022

Obesity is ubiquitous in many developed countries, and it is frequently associated with health problems. Furthermore, those who are overweight or obese are frequently stigmatized in their daily lives....

A large intrathoracic goiter with tracheal stenosis: Complete resection using a robot-assisted thoracoscopic approach.

May 16, 2022

Growing intrathoracic goiters may compress surrounding organs and deteriorate the cardiopulmonary function. Treating such cases requires carefully considering how to maintain oxygenation and resect th...

Maternal thyroid disease in pregnancy and timing of pubertal development in sons and daughters.

May 16, 2022

To study whether maternal thyroid disease in pregnancy is associated with pubertal timing in sons and daughters.Cohort study.National birth cohort and health registers.A total of 15,763 mothers and ch...

Proximal junctional fractures after long-segment instrumented fusion: comparisons between upper instrumented vertebrae and upper instrumented vertebrae + 1.

May 16, 2022

Proximal junctional failure (PJF) is a well-known complication after long-segment (at least 4 vertebral levels) instrumented fusion. The etiologies of PJF include degenerative processes or are fractur...

Ipriflavone suppresses NLRP3 inflammasome activation in host response to biomaterials and promotes early bone healing.

May 16, 2022

Emerging studies have shown that immune response to biomaterial implants plays a central role in bone healing. Ipriflavone is clinically used for osteoporosis. However, the mechanism of ipriflavone in...

Exploring the association between birthweight and breast cancer using summary statistics from a perspective of genetic correlation, mediation, and causality.

May 16, 2022

Previous studies demonstrated a positive relationship between birthweight and breast cancer; however, inconsistent, sometimes even controversial, observations also emerged, and the nature of such rela...

Long-term effects of orchiopexy and orchiectomy on the testes of rats with testicular torsion.

May 16, 2022

Ischemia/reperfusion injury occurs after testicular torsion, levels of free oxygen radicals and inflammatory cytokines are increased in both the torsional and contralateral testis, leading to testicul...

Localisation and in silico based functional analysis of miR-202 in bull testis.

May 16, 2022

Bull fertility is pivotal to the prosperity of the cattle industry worldwide. miR-202 has been shown to be gonad specific and to have key roles in gonad function in different species. To further under...

Dental age estimation with two different methods in paediatric patients with hypothyroidism.

May 09, 2022

This case-control study aimed to evaluate dental age estimation in children with hypothyroidism using two different methods in order to contribute to the literature about the most accurate method.In t...