Managing insomnia and other sleep disorders in IBD must first start with raising awareness of the IBD-sleep connection among clinicians and patients. “Previously, researchers have shown that poor sleep predicts adverse outcomes for patients with...
Gastroenterology
RELEVANT ARTICLES IN Gastroenterology
Reduced Opioids After Colorectal Surgery
Reduced Opioids After Colorectal Surgery
The following is a summary of "Discharge Prescribing Protocol Decreases Opioids in Circulation and Does Not Increase Refills After Colorectal Surgery," published in the June 2023 issue of Diseases of the Colon and Rectum by Bauer et al. Approximately 10% of...
Post-translational modification of CDK1-STAT3 signaling by fisetin suppresses pancreatic cancer stem cell properties.
Post-translational modification of CDK1-STAT3 signaling by fisetin suppresses pancreatic cancer stem cell properties.
Pancreatic cancer stem cells (CSCs) promote pancreatic ductal adenocarcinoma (PDAC) tumorigenesis and chemoresistance. Cyclin-dependent kinase 1 (CDK1) plays an important role in tumor initiation in other tumors, but the function of CDK1 in PDAC remains unclear....
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Development and Current State of Digital Therapeutics for Irritable Bowel Syndrome.
Development and Current State of Digital Therapeutics for Irritable Bowel Syndrome.
Irritable bowel syndrome (IBS) is a common, debilitating disorder characterized by abdominal pain and disordered bowel habits. Current pharmacological treatments often provide incomplete symptom relief and may be poorly tolerated. Furthermore, alleviation of...
Association of Selinexor Dose Reductions With Clinical Outcomes in the BOSTON Study.
Association of Selinexor Dose Reductions With Clinical Outcomes in the BOSTON Study.
Dose modifications in response to adverse events (AEs) can maintain tumor response and improve therapy tolerability. We conducted a post-hoc analysis of the efficacy and safety of reduced selinexor doses in the BOSTON trial (NCT03110562).Efficacy, safety, and...
Disease burden, comorbidities and antecedents of chronic cough phenotypes in Australian adults.
Disease burden, comorbidities and antecedents of chronic cough phenotypes in Australian adults.
While adult chronic cough has high burden, its phenotypes, particularly those without aetiologically related underlying conditions, are understudied. We investigated the prevalence, lung function and comorbidities of adult chronic cough phenotypes.Data from 3608...
HPV-Positive Results Risk Stratification with Extended Cytology and Genotyping
HPV-Positive Results Risk Stratification with Extended Cytology and Genotyping
The following is a summary of “Risk stratification of HPV-positive results using extended genotyping and cytology: Data from the baseline phase of the Onclarity trial,” published in the July 2023 issue of Gynecologic Oncology by Stoler et al. Optimizing the balance...
Artificial Intelligence Has High Performance for Detecting PCOS
Artificial Intelligence Has High Performance for Detecting PCOS
FRIDAY, Sept. 22, 2023 (HealthDay News) -- Artificial intelligence (AI) and machine learning (ML) have high diagnostic and classification performance for detection of polycystic ovarian syndrome (PCOS), according to a review published online Sept. 18 in Frontiers...
Early Outcome of Neonates Admitted with Meconium Aspiration Syndrome.
Early Outcome of Neonates Admitted with Meconium Aspiration Syndrome.
Meconium aspiration syndrome is one of the commonest cause of respiratory distress in neonates. The incidence is still high in developing world. This study aims to study the clinical characteristics and early outcome of neonates admitted for meconium aspiration...
Association Between Mycophenolate Mofetil Use and Subsequent Infections Among Hospitalized Patients with Systemic Lupus Erythematosus: A Nested Case-Control Study.
Association Between Mycophenolate Mofetil Use and Subsequent Infections Among Hospitalized Patients with Systemic Lupus Erythematosus: A Nested Case-Control Study.
The association between mycophenolate mofetil (MMF) and infection in patients with systemic lupus erythematosus (SLE) has not been clarified. This study evaluated the degree and factors in effect of MMF use on infection in patients with SLE.A hospitalized-based...
The effect of prenatal anxiety on prenatal attachment in high-risk pregnant women and related factors: a cross-sectional study.
The effect of prenatal anxiety on prenatal attachment in high-risk pregnant women and related factors: a cross-sectional study.
High-risk pregnant women experience stress and anxiety. Anxiety may affect prenatal attachment. This study aimed to examine the effect of anxiety on prenatal attachment in high-risk pregnant women. The study was cross-sectional and conducted on 290 high-risk...
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ASCO GI 2023
The latest news from ASCO GI 2023, including features, abstracts, information about the conference, and more.
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Medical Fiction: Ronald and the Vassal’s Vessel
Medical Fiction: Ronald and the Vassal’s Vessel
This is one of a collection of stories that are like “Final Destination” meets “The Monkey’s Paw” (W. W. Jacobs, 1902). As such, they are tragedies more than either mysteries or horror, and would appeal most to readers who enjoy the inexorable pull of a story arc...
What Does Negligence Really Mean?
What Does Negligence Really Mean?
Any discussion with doctors about avoiding liability for malpractice is hampered from the start because “negligence” is a very charged term. It conjures up images of a slipshod and blundering individual and so doctors understandably immediately become resistant....
Medical Fiction: Knitter Nikka and the Knacker
Medical Fiction: Knitter Nikka and the Knacker
Vascular surgeon Nikka loves metalwork and knitting. Her hobbies come in handy during a run-in with Jeremy, whose privileged life unraveled after his dad died.
CME / CE
CME/CE: Updated Guidance on Managing C. difficile Infection
This course describes the newest recommendations on preferred and alternative treatments for diarrhea and colitis due to Clostridioides difficile infection (CDI).
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Armchair Exercise
Armchair Exercise
"The handle of your recliner does not qualify as an exercise machine."
Bear Attack
Bear Attack
"You went camping and a bear mistook your blood for honey. Would you mind if I order a diabetes test for you?"
Soft Bones and Hard Arteries
Soft Bones and Hard Arteries
"My bones are getting softer, but my arteries are getting harder, so it balances out!"
BUSINESS OF MEDICINE
Is Medical Crowdfunding a Sinew of the Healthcare Arena?
Is Medical Crowdfunding a Sinew of the Healthcare Arena?
A Medscape article reported on a 2023 JAMA Neurology study in that found medical crowdfunding, the practice of creating digital campaigns to raise money for health-related expenses, for neurologic disorders surged within 9 years at a yearly average rate of 44%. Of...
How to Handle Patients Who Leave Against Medical Advice
How to Handle Patients Who Leave Against Medical Advice
Risk and reward are inherent to providing medical care. As such, it is essential that patients understand all potential outcomes when making personal healthcare decisions, including the decision to forgo care against medical advice (AMA). According to medical...
Areas of Revenue Cycle Management That Require Significant Expertise
Areas of Revenue Cycle Management That Require Significant Expertise
Revenue cycle management (RCM) can be a tricky task for healthcare organizations. Certain elements of RCM in particular require more subject-matter expertise. According to a survey from AKASA, a leading healthcare artificial intelligence (AI) developer, coding,...
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