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Irritable Bowel Syndrome / IBS

Reducing Opioid-Induced Constipation Post-Cardiac Surgery: An Improvement Project in a Pediatric Cardiac Intensive Care Unit.

Jan 24, 2022

Pain management with opioids and underutilization of prophylaxis for constipation can prolong a patient's hospital length of stay and impede pain management efforts.In pediatric postoperative cardiac ...

Impact of intestinal disorders on central and peripheral nervous system diseases.

Jan 17, 2022

Brain injuries and neurological diseases have a significant impact on the gut microbiome and the gut barrier. Reciprocally, gut disorders, such as Inflammatory Bowel Syndromes (IBS), can affect the de...

Postoperative organ space infection (OSI) following appendectomy: early term evaluation for pediatric population.

Jan 10, 2022

No consensus has been reached on the duration of antibiotic prophylaxis for postoperative organ space infection (OSI) following appendectomy. This study investigated the influence of antibiotic admini...

Prediagnostic expressions in health records predict mortality in Parkinson's disease: A proof-of-concept study.

Jan 10, 2022

The relationship of prodromal markers of PD with PD mortality is unclear. Electronic health records (EHRs) provide a large source of raw data that could be useful in the identification of novel releva...

Acute Bulbar Palsy and Ophtalmoplegia Associated With Anti-GT1a IgG Antibodies.

Jan 03, 2022

Although several variants of Guillain-Barré syndrome (GBS) have been described, they are uncommon, and the atypical clinical presentation of patients makes the diagnosis challenging. This article rep...

Autonomic symptoms are predictive of dementia with Lewy bodies.

Dec 27, 2021

Autonomic symptoms are common in patients with dementia with Lewy bodies (DLB). Although autonomic dysfunction is considered as one of the primary early markers in patients with DLB, there are few stu...

Emotional stress responsivity of patients with IBS - a systematic review.

Dec 27, 2021

Irritable bowel syndrome (IBS) is a highly prevalent disorder of the gut-brain interaction characterized by abdominal discomfort and pain associated with altered bowel habits in the absence of structu...

Managing Patients With IBS: Analyzing Preferences for Healthcare Delivery

Dec 22, 2021

A key element to optimizing the management of IBS is to have a strong physician-patient relationship that allows professional advice to be individualized. “IBS is a chronic condition for which there...

Crizotinib versus Alectinib for the Treatment of ALK-Positive Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis.

Dec 20, 2021

Crizotinib and alectinib are the two most commonly used anaplastic lymphoma kinase (ALK) inhibitors for ALK-positive non-small cell lung cancer (NSCLC). We compared their antitumor efficacies and adve...

Exploring Gluten Avoidance Practices in Patients With IBS

Dec 10, 2021

According to recent estimates, IBS affects approximately 11% of people globally, with the disorder occurring more frequently in women and young adults than in other patient groups. A diagnosis of IBS ...

Targeted therapy of irritable bowel syndrome with anti-inflammatory cytokines.

Dec 06, 2021

Irritable bowel syndrome (IBS) is a multifactorial disease of which infection, as well as inflammation, has recently been considered as an important cause. Inflammation works as a potential pathway fo...

Incidence and risk factors of nonalcoholic fatty liver disease after total pancreatectomy: A first multicenter prospective study in Japan.

Dec 06, 2021

This study aimed to prospectively assess the current prevalence and risk factors of nonalcoholic fatty liver disease (NAFLD) after total pancreatectomy (TP).Between August 2015 and December 2017, we p...

Metformin-associated lactic acidosis exacerbated by acute kidney injury in an overseas traveler.

Nov 29, 2021

We report the case of metformin-associated lactic acidosis (MALA) exacerbated by acute kidney injury (AKI) in a 65-year-old Asian American woman who was an overseas traveler. She had vomiting and diar...

Frequency and diversity of small plasmids in mesophilic Aeromonas isolates from fish, water and sediment.

Nov 22, 2021

Plasmids are autonomous genetic elements ubiquitously present in bacteria. In addition to containing genetic determinants responsible for their replication and stability, some plasmids may carry genes...

Inter-group conflict affects inter-brain synchrony during synchronized movements.

Nov 22, 2021

Interpersonal synchrony refers to alignment in time of interacting individuals. Recent neuroimaging findings indicate that the inferior frontal gyrus (IFG) - a core region of the observation-execution...

Large trichobezoar associated with misdiagnosis, a rare case report with a brief literature review.

Nov 08, 2021

Trichobezoar is a rare disorder that almost exclusively affects young females. Up to 90% between 13 and 20 years of age. The current study aims to report and discuss a rare case of Misdiagnosis of Tr...

Quality of life after VATS lung resection and SABR for early-stage non-small cell lung cancer: A longitudinal study.

Nov 08, 2021

Video-assisted thoracoscopic (VATS) lung resection is the recommended curative treatment for early-stage non-small cell lung cancer (NSCLC). Patients considered at high surgical risk, are treated with...

Chronic constipation as a risk factor for colorectal cancer: results from a nationwide, case-control study.

Oct 25, 2021

Prolonged colon transit times may increase contact time between potential carcinogens in the stool and the colonic mucosa. Nonetheless, previous studies have yielded conflicting results connecting chr...

Exposure-response analysis of adverse events associated with molibresib and its active metabolites in patients with solid tumors.

Oct 18, 2021

Molibresib (GSK525762) is an investigational orally bioavailable small molecule bromodomain and extra-terminal (BET) protein inhibitor for the treatment of advanced solid tumors. In the first-time-in-...

Treatment outcome with a selective RET tyrosine kinase inhibitor selpercatinib in children with multiple endocrine neoplasia type 2 and advanced medullary thyroid carcinoma.

Oct 18, 2021

Medullary thyroid carcinoma (MTC) in the context of multiple endocrine neoplasia type 2 (MEN2) is caused by mutations in the RET proto-oncogene. Therefore, in children with MEN2 and advanced MTC, the ...