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Gastroenterology Newsletter

The Tale of Enzymes

YAP and TAZ are the most important components of the transcriptional co-activators and hence, are able to downstream the data in the best possible manner. This is important to realize that the people are in the position to...

Tumor-associated macrophages derived from cancer stem cells.

Macrophages are the most abundant immune cells in the microenvironment of solid tumors. The present study displayed histological and immunohistochemical analyses of a malignant tumor model developed from cancer stem cells (CSCs)...

COVID Vaccine Trials Move at Warp Speed, But Recruiting Black Volunteers Takes Time

The National Institutes of Health has suggested minorities should be overrepresented in COVID-19 vaccine trials — perhaps at rates that are double their percentage of the U.S. population. But efforts to recruit patients from racial minority groups are just beginning, while some trials have already advanced to phase 3.

Risankizumab for Moderate to Severe Crohn’s Disease

Crohn’s disease is an inflammatory bowel disease (IBD) characterized by the inflammation of the digestive tract, leading to abdominal pain, diarrhea, malnutrition, and cancer. Risankizumab is a humanized monoclonal that...

Outcomes of Obesity in Acute Alcoholic Hepatitis

Acute alcoholic hepatitis is a condition of inflammation of the liver caused by drinking alcohol. While acute alcoholic hepatitis in itself is a serious condition, the complications increase in obese patients. The objective of...

Glecaprevir Plus Pibrentasvir for Chronic Hepatitis C

Hepatitis C is an infection of the liver characterized by inflammation of the organ, and in some cases, cancer. Glecaprevir, a pangenotypic direct-acting antiviral regimen, given in combination with pibrentasvir, is approved to...

Hyperthermic Intraperitoneal Chemotherapy for Colon Cancer

Locally advanced colon cancer refers to tumors localized to adjacent organs in patients without distant metastases. Around a quarter of patients with locally advanced colon cancer are likely to develop peritoneal metastases, a...

AMG 714 in Adults with Coeliac Disease and Gluten Challenge

Coeliac disease refers to a condition where the immune system attacks the tissues of the body when a person eats gluten. This condition damages the small intestine and inhibits the absorption of nutrients. AMG 714 a monoclonal...

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