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Online Tool Aids Decision Making About Breast Cancer Treatment

Findings based on assessment of the interactive iCanDecide tool

Fecal Immunochemical Test Predicts Mucosal Healing in UC

Meta-analysis finds FIT is a reliable, non-invasive marker for mucosal healing in ulcerative colitis

Treatment Model Linked to Drop in Post-Incarceration Overdoses

Introduction of model to treat opioid use disorder tied to drop in overdose deaths after incarceration

Obesity Linked to Improved Survival in Metastatic Melanoma

Survival benefit limited to male patients receiving targeted therapy, immunotherapy

Accelerated Lung Function Decline for Women Who Clean

Faster decline in women responsible for cleaning at home, occupational cleaners, but not for men

Mental Stress-Induced Myocardial Ischemia Risk Up for Women

Peripheral vasoconstriction, microvascular dysfunction may affect MSIMI risk in women only

Perioperative Glucose but Not A1C Predicts Surgical Outcomes

A1C is not associated with increased 30-day mortality after controlling for glucose

Chronic Opioid Users May Wish to Taper Opioid Use

In study completers, median morphine equivalent daily dose fell from 288 mg to 150 mg in four months

Prenatal Valproate Exposure May Impact School Performance

Significant decrease in school performance for offspring exposed to valproate versus lamotrigine

All Physical Activity Tied to Reduced Mortality in Older Men

Similarly beneficial effect for accumulation of activity in bouts of ≥10 minutes, sporadic minutes

Increasing Demands Leading to Pharmacist Burnout

Strategies to address burnout include taking vacation time, reflecting on work, relying on others for help

No Evidence Use of SEP-1 Bundle Ups Survival in Sepsis

Neither the sepsis management bundle nor its interventions improve survival for adults with sepsis

In A-Fib Patients, Stroke Risk Higher for Blacks Than Whites

Higher risk of ischemic stroke seen before, after atrial fibrillation diagnosis compared with whites

Odds of ARDS Up After Cardiac Surgery During Flu Season

Cardiac surgery during flu season is independent risk factor for acute respiratory distress syndrome

Aspirin, Rivaroxaban Similar After Total Hip, Knee Arthroplasty

Extended prophylaxis with aspirin no different from rivaroxaban for preventing venous thromboembolism

Automated Central System Offers Time Savings for Pharmacists

Cart-fill process using new automated system is more efficient, frees up time for other roles

Long-Term Inhaled Corticosteroid Use May Raise Fracture Risk

Long-term inhaled corticosteroid use for COPD tied to small increased risk of hip, upper extremity fracture

Molecular Markers May ID Alzheimer’s Before Clinical Onset

Amyloid-positive PSEN1 E280A mutation carriers have elevated levels of tau deposition before onset

Influenza A(H3N2) Viruses Predominate 2017-2018 Season

Vaccine effectiveness estimated at 25 percent against A(H3N2)

Anti-Heroin Vaccine Shows Promise Against Lethal Doses

TLR9 agonist in presence of alum is stable over 30 days, elicits strong anti-heroin antibody titers

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