BMPs as new insulin sensitizers: enhanced glucose uptake in mature 3T3-L1 adipocytes via PPARγ and GLUT4 upregulation.

Scientific reports 2017 12 087(1) 17192 doi 10.1038/s41598-017-17595-5 Abstract Insulin-resistance is the main cause of type 2 diabetes. Here we describe the identification and characterization of BMP2

Bivariate longitudinal data analysis: a case of hypertensive patients at Felege Hiwot Referral Hospital, Bahir Dar, Ethiopia.

BMC research notes 2017 12 0810(1) 722 doi 10.1186/s13104-017-3044-4 Abstract OBJECTIVE Longitudinal data are often collected to study the evolution of biomedical markers. The study of the

General practitioners’ awareness of depressive symptomatology is not associated with quality of life in heart failure patients – cross-sectional results of the observational RECODE-HF Study.

BMC family practice 2017 12 0818(1) 100 doi 10.1186/s12875-017-0670-9 Abstract BACKGROUND Depression is a common comorbidity in patients with chronic heart failure (HF) and linked to a

Temporal distribution and genetic variants in influenza A(H1N1)pdm09 virus circulating in Mexico, seasons 2012 and 2013.

PloS one 2017 12 0812(12) e0189363 doi 10.1371/journal.pone.0189363 Abstract The 2012 and 2013 annual influenza epidemics in Mexico were characterized by presenting different seasonal patterns. In 2012

Full-Length Genome Sequence of a Chikungunya Virus Isolate from the 2017 Autochthonous Outbreak, Lazio Region, Italy.

Genome announcements 2017 12 075(49) pii e01306-17 Abstract We report here the genome sequence of a human chikungunya virus isolate from the ongoing autochthonous outbreak in central

An unusual cause of hypoxia: getting to the heart of the matter.

Echo research and practice 2017 12 07() pii ERP-17-0055 Abstract A 63 year old female presented to hospital with progressive exertional dyspnoea over a 6 month period.

Effect of Qianghuo Erhuang Decoction on T Regulatory and T Helper 17 Cells in Treatment of Adjuvant-induced Arthritis in Rats.

Scientific reports 2017 12 087(1) 17198 doi 10.1038/s41598-017-17566-w Abstract QianghuoErhuang Decoction (QED) is an effective recipe in treating rheumatoid arthritis. The present study aimed to explore the

Elevated serum β2-microglobulin in individuals coinfected with hepatitis B and hepatitis D virus in a rural settings in Southwest Nigeria.

BMC research notes 2017 12 0810(1) 719 doi 10.1186/s13104-017-3015-9 Abstract OBJECTIVE Coinfection of hepatitis B virus (HBV) with hepatitis D virus (HDV) has being reported to increase

Prevalence and related risk factors of chronic kidney disease among adults in Luxembourg: evidence from the observation of cardiovascular risk factors (ORISCAV-LUX) study.

BMC nephrology 2017 12 0818(1) 358 doi 10.1186/s12882-017-0772-6 Abstract BACKGROUND Evidence on stages of renal impairment and related risk factors in Luxembourg is lacking. This study aimed

C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid.

PloS one 2017 12 0812(12) e0189017 doi 10.1371/journal.pone.0189017 Abstract Complement activation correlates to rheumatoid arthritis disease activity, and increased amounts of the complement split product C5a is

Complete Genome Sequences of Two Human Parainfluenza Virus Type 3 Isolates Collected in Brazil.

Genome announcements 2017 12 075(49) pii e01192-17 Abstract Here, we present the complete genome sequences of two human parainfluenza virus type 3 (HPIV-3) isolates collected from hospitalized

microRNA-4331 promotes TGEV-induced mitochondrial damage via targeting RB1, up-regulating IL1RAP, and activating p38 MAPK pathway in vitro.

Molecular & cellular proteomics : MCP 2017 12 07() pii mcp.RA117.000432 Abstract Transmissible gastroenteritis virus (TGEV), a member of the coronaviridae family, could cause fatal diarrhea of

Structural abnormalities in islets from very young children with cystic fibrosis may contribute to cystic fibrosis-related diabetes.

Scientific reports 2017 12 087(1) 17231 doi 10.1038/s41598-017-17404-z Abstract Cystic fibrosis (CF)-related diabetes (CFRD) is thought to result from beta-cell injury due in part to pancreas exocrine

Divergent susceptibilities to AAV-SaCas9-gRNA vector-mediated genome-editing in a single-cell-derived cell population.

BMC research notes 2017 12 0810(1) 720 doi 10.1186/s13104-017-3028-4 Abstract OBJECTIVE Recombinant adeno-associated virus (AAV)-based vectors are characterized by their robust and safe transgene delivery. The CRISPR/Cas9

Hyporesponsiveness of natural killer cells and impaired inflammatory responses in critically ill patients.

BMC immunology 2017 12 0818(1) 48 doi 10.1186/s12865-017-0231-y Abstract BACKGROUND To investigate natural killer (NK) cell activity, circulating cytokine level and peripheral blood mononuclear cell (PBMC) cytokine

The impact of different anti-vascular endothelial growth factor treatment regimens on reducing burden for caregivers and patients with wet age-related macular degeneration in a single-center real-world Japanese setting.

PloS one 2017 12 0812(12) e0189035 doi 10.1371/journal.pone.0189035 Abstract OBJECTIVE To describe the burden associated with different anti-vascular endothelial growth factor (VEGF) treatment strategies for wet age-related

Somatic STAT3 mutations in the Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia.

Haematologica 2017 12 07() pii haematol.2017.175729 Abstract Felty syndrome is a rare disease defined by neutropenia, splenomegaly, and rheumatoid arthritis. Sometimes the differential diagnosis between Felty syndrome

The Impact of a Mobile Diabetes Health Intervention on Diabetes Distress and Depression Among Adults: Secondary Analysis of a Cluster Randomized Controlled Trial.

JMIR mHealth and uHealth 2017 12 075(12) e183 doi 10.2196/mhealth.8910 Abstract BACKGROUND Diabetes is a complex, demanding disease that requires the constant attention of patients. The burden

New insights into the mechanism of nickel superoxide degradation from studies of model peptides.

Scientific reports 2017 12 087(1) 17194 doi 10.1038/s41598-017-17446-3 Abstract A series of small, catalytically active metallopeptides, which were derived from the nickel superoxide dismutase (NiSOD) active site

The impacts of baseline ventilator parameters on hospital mortality in acute respiratory distress syndrome treated with venovenous extracorporeal membrane oxygenation: a retrospective cohort study.

BMC pulmonary medicine 2017 12 0817(1) 181 doi 10.1186/s12890-017-0520-5 Abstract BACKGROUND Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a valuable life support in acute respiratory distress syndrome (ARDS)

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