Impact of Ixekizumab Treatment on Depressive Symptoms and Systemic Inflammation in Patients with Moderate-to-Severe Psoriasis: An Integrated Analysis of Three Phase 3 Clinical Studies.

Psychotherapy and psychosomatics 2017 09 1486(5) 260-267 doi 10.1159/000479163 Abstract BACKGROUND Depression is a common comorbidity in psoriasis, and both conditions are associated with systemic inflammation. The

Molecular clustering of patients with diabetes and pulmonary tuberculosis: A systematic review and meta-analysis.

PloS one 2017 09 1312(9) e0184675 doi 10.1371/journal.pone.0184675 Abstract INTRODUCTION Many studies have explored the relationship between diabetes mellitus (DM) and tuberculosis (TB) demonstrating increased risk of

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.

Nature 2017 09 13() doi 10.1038/nature24029 Abstract Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate pathologic inflammation in allergic asthma. However, the

Delinquency and sexual experiences across adolescence: does depression play a role?

The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 2017 09 1322(4) 298-304 doi 10.1080/13625187.2017.1374361 Abstract PURPOSE

Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidine derivatives.

Organic & biomolecular chemistry 2017 09 13() doi 10.1039/c7ob02085f Abstract Two facile and efficient one-step procedures for the regioselective synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a]pyrimidines have been developed,

The efficacy of stretching exercises to reduce posterior shoulder tightness acutely in the postoperative population: a single blinded randomized controlled trial.

Physiotherapy theory and practice 2017 09 13() 1-10 doi 10.1080/09593985.2017.1376020 Abstract BACKGROUND Posterior shoulder tightness (PST) is a postoperative complication leading to pain, impaired mobility, and reduced

Are children rational decision makers when they are asked to value their own health? A contingent valuation study conducted with children and their parents.

Health economics 2017 09 13() doi 10.1002/hec.3562 Abstract Despite the importance of including children’s preferences in the valuation of their own health benefits, no study has investigated

The Mortality and Myocardial Effects of Antidepressants Are Moderated by Preexisting Cardiovascular Disease: A Meta-Analysis.

Psychotherapy and psychosomatics 2017 09 1486(5) 268-282 doi 10.1159/000477940 Abstract BACKGROUND Antidepressants (ADs) are commonly prescribed medications, but their long-term health effects are debated. ADs disrupt multiple

Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.

PLoS pathogens 2017 09 1313(9) e1006614 doi 10.1371/journal.ppat.1006614 Abstract Extensive shielding by N-glycans on the surface of the HIV envelope glycoproteins (Env) restricts B cell recognition of

Rabies screen reveals GPe control of cocaine-triggered plasticity.

Nature 2017 09 13() doi 10.1038/nature23888 Abstract Identification of neural circuit changes that contribute to behavioural plasticity has routinely been conducted on candidate circuits that were preselected

Biodegradable Viral Nanoparticle/Polymer Implants Prepared via Melt-Processing.

ACS nano 2017 09 13() doi 10.1021/acsnano.7b02786 Abstract Viral nanoparticles have been utilized as a platform for vaccine development and are a versatile system for the display

Correction: Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism.

Food & function 2017 09 13() doi 10.1039/c7fo90032e Abstract Correction for ‘Lactobacillus casei CCFM419 attenuates type 2 diabetes via a gut microbiota dependent mechanism’ by Gang Wang

Efficacy and safety of saxagliptin in combination with insulin in Japanese patients with type 2 diabetes mellitus: a 16-week double-blind randomized controlled trial with a 36-week open-label extension.

Expert opinion on pharmacotherapy 2017 09 13() doi 10.1080/14656566.2017.1379990 Abstract BACKGROUND We examined the efficacy and safety of saxagliptin as an add-on to insulin in Japanese patients

Feeding live invertebrate prey in zoos and aquaria: Are there welfare concerns?

Zoo biology 2017 09 13() doi 10.1002/zoo.21378 Abstract Invertebrates constitute more than 90% of all species on earth, however, as a rule, humans do not regard invertebrates

Poorer Long-Term Outcomes among Persons with Major Depressive Disorder Treated with Medication.

Psychotherapy and psychosomatics 2017 09 1486(5) 302-304 doi 10.1159/000479162 Abstract

Identification of diverse viruses in upper respiratory samples in dromedary camels from United Arab Emirates.

PloS one 2017 09 1312(9) e0184718 doi 10.1371/journal.pone.0184718 Abstract Camels are known carriers for many viral pathogens, including Middle East respiratory syndrome coronavirus (MERS-CoV). It is likely

Urinary CXCL10 chemokine is associated with alloimmune and virus compartment-specific renal allograft inflammation.

Transplantation 2017 09 12() doi 10.1097/TP.0000000000001931 Abstract BACKGROUND Urinary CXCL10 is a promising biomarker for subclinical tubulointerstitial inflammation, but limited data exists regarding its correlation with (micro)vascular

EAACI Guidelines on Allergen Immunotherapy: Prevention of allergy.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 2017 09 13() doi 10.1111/pai.12807 Abstract Allergic diseases are common and

Patient characteristics affect the response to ketamine and opioids during the treatment of vaso-occlusive episode-related pain in sickle cell disease.

Pediatric research 2017 09 13() doi 10.1038/pr.2017.197 Abstract BackgroundN-methyl-D-aspartate receptor activation has been implicated in the pathobiology of inflammatory, nociceptive and neuropathic pain, opioid tolerance, opioid-induced hyperalgesia,

Cardiac side effects of bruton tyrosine kinase (BTK) inhibitors.

Leukemia & lymphoma 2017 09 13() 1-11 doi 10.1080/10428194.2017.1375110 Abstract The development of bruton tyrosine kinase inhibitors (BTKi) has been a significant advancement in the treatment of

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