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Infectious Disease General

Impact of C/T vs. Best Alternative Therapy on Clinical Outcomes in Patients

Oct 13, 2022

Pseudomonas aeruginosa infections that are MDR (multidrug-resistant), XDR (extensively drug-resistant), or DTR (difficult-to-treat) are becoming increasingly difficult to treat. Treatment of MDR and X...

Patient-Reported Outcomes (PROs) in HIV Infection

Oct 12, 2022

This research aimed to determine whether PROs (patient-reported outcome measures) should be utilized with HIV-positive individuals (PLHIV). To assist in deciding which assertions ought to be substanti...

COVID-19 Vaccine Booster Strategies: Emerging Viral Variants

Oct 10, 2022

The severe burden of COVID-19 has been much reduced because of vaccinations, allowing non-pharmaceutical therapies to be discontinued. However, vaccination techniques need to be reviewed due to declin...

Bacterial Infections Confer a Risk of Progression to ACLF

Oct 10, 2022

In patients with Hepatitis B virus (HBV)-related compensated liver cirrhosis and severe hepatitis flares, the purpose of the study was to identify risk factors for bacterial infections (BIs) and exami...

Microfluidic Antigen LumiraDx SARS-CoV-2 & Flu A/B Test

Oct 10, 2022

This year's coronavirus disease (COVID-19) was challenging to diagnose because its symptoms were similar to the flu. In addition, different tactics for containing and treating the 2 illnesses were req...

PASC Excess After the First Wave of the Pandemic

Oct 10, 2022

For a study, researchers sought to evaluate the timing of the initial COVID-19 among patients who self-reported having post-acute sequelae of COVID-19 (PASC). Using the chi-squared test, they examined...

Monovalent Vaccine Administration in Infants Receiving DTaP-based Combination Vaccines

Sep 22, 2022

Vaccinations against polio, whooping cough, Haemophilus influenzae type b (Hib), and hepatitis B virus (HepB) are all given to infants in the first 6 months of life in the United States according to t...

Influenza Vaccine Effectiveness in Children and Adolescents in the United States in the 2019-2020 Season

Sep 22, 2022

Manufacturing influenza vaccines in eggs can lead to mutations that reduce antigenicity. The inactivated quadrivalent influenza vaccine (IIV4c) made from mammalian cells may be more effective than vac...

Spatiotemporal trends in US Rotavirus laboratory detections post-vaccine introduction 2009-2021

Sep 22, 2022

In the 15 years following the release of the first rotavirus vaccination in the United States in 2006, annual rotavirus activity in the country followed a clear spatiotemporal pattern, with the highes...

Congenital Toxoplasmosis with Concomitant Cytomegalovirus Infection in Dichorionic Twins

Sep 22, 2022

Cytomegalovirus (CMV) congenital infection and toxoplasmosis share comparable clinical manifestations. The long-term effects of both infections can be lessened with prompt diagnosis and treatment. Alt...

GI Manifestations With Acute SARS-CoV-2 Infection & MIS-C

Sep 22, 2022

Identify the frequency of gastrointestinal (GI) manifestations of acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in hospitalized children (MIS-C) and the outcomes that...

Active Surveillance With Seroprevalence-based Infection Rates: Racial Disparities With Pediatric SARS-CoV-2

Sep 22, 2022

There have been observed racial differences in the rates of SARS-CoV-2 infection, hospitalization, and multisystem inflammatory syndrome in children (MIS-C). These studies, however, have been incomple...

Tedizolid and Comparator Agent Activity in Pediatric Patients Against Gram-positive Isolates

Sep 22, 2022

The United States Food and Drug Administration (FDA) initially approved tedizolid in 2014 for the treatment of acute bacterial skin and skin structure infections in adults, and in 2020, the FDA increa...

Relapse Incidence & Predictors After Antiviral Therapy

Sep 22, 2022

In the case of chronic hepatitis B (CHB) in children, there are currently no predetermined cutoff points for treatment. The purpose of this research was to assess the frequency of relapse following th...

Bacterial Meningitis-associated Hydrocephalus Prediction Using Nomogram

Sep 22, 2022

With this study, researchers aimed to create a nomogram that could predict which children with bacterial meningitis would develop hydrocephalus. The children with bacterial meningitis admitted to a ho...

PRG & Recurrent Varicella: Overlapping Signs & Symptoms

Sep 22, 2022

A viral cause has been hypothesized for Pityriasis rosea Gibert (PRG) since its symptoms are similar to those of other prevalent infectious children disorders, but no agent has been discovered as of y...

Early Transition to Oral Antimicrobial Therapy in SAB & AHO Children

Sep 22, 2022

Acute hematogenous osteomyelitis (AHO) is commonly complicated by Staphylococcus aureus bacteremia (SAB), yet there is a lack of information regarding the recommended time of parenteral antibiotics be...

COVID-19 in Children: Epidemiologic, Clinical Characteristics, & RT-qPCR Ct Values

Sep 22, 2022

SARS-influence CoV-2's on children was initially unknown. Real-time qPCR confirms COVID-19 diagnosis. RT-qPCR cycle threshold (Ct) values are inversely proportional to viral load and indirectly measur...

Acylcarnitines and Fat Oxidation Gene Genetic Variation in HIV-infected, ARV-treated Children With and Without Myopathy

Sep 22, 2022

Patients who have been exposed to antiretrovirals (ARVs) have been reported to experience mitochondrial toxicity leading to myopathy and lactic acidosis. Researchers have postulated that myopathy in A...

CRGNB Gut Decolonization in Neonatal & Pediatric Patients

Sep 22, 2022

Including carbapenem-resistant Gram-negative bacteria (CRGNB), the gut microbiome may be transformed into a reservoir of resistant organisms after antibiotic exposure. Little is understood about the r...