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HIV/AIDS

Network centrality for the identification of biomarkers in respondent-driven sampling datasets.

Aug 26, 2021

Networks science techniques are frequently used to provide meaningful insights into the populations underlying medical and social data. This paper examines SATHCAP, a dataset related to HIV and drug u...

Improved kala-azar case management through implementation of health facility-based sentinel sites surveillance system in Bihar, India.

Aug 26, 2021

Visceral leishmaniasis (VL), also known as kala-azar (KA), is a neglected vector-borne disease, targeted for elimination, but several affected blocks of Bihar are posing challenges with the high incid...

A randomized controlled trial evaluating the effects of a family-centered HIV care model on viral suppression and retention in care of HIV-positive children in Eswatini.

Aug 26, 2021

A family-centered care model (FCCM) providing family-based HIV services, rather than separate adult/pediatric services, has been proposed to increase pediatric retention and treatment adherence.Eight ...

Bystander CD4 T-cell death is inhibited by broadly neutralizing anti-HIV antibodies only at levels blocking cell-to-cell viral transmission.

Aug 23, 2021

The progressive loss of CD4+T cells during HIV infection of lymphoid tissues involves both the apoptotic death of activated and productively infected CD4 T cells and the pyroptotic death of large numb...

HIV-1 Tat and cocaine impact astrocytic energy reservoir influence on miRNA epigenetic regulation.

Aug 23, 2021

Astrocytes are the primary regulator of energy metabolism in the central nervous system (CNS), and impairment of astrocyte's energy resource may trigger neurodegeneration. HIV infections and cocaine u...

Diagnostic accuracy of uterine artery and spiral artery Doppler for evaluation of endometrial pathology in postmenopausal bleeding.

Aug 23, 2021

Traditional diagnostic workup for Endometrial carcinoma in women with post-menopausal bleeding (PMB) involves endometrial biopsy. Addition of colour and power Doppler ultrasound to transvaginal ultras...

Multiple Sexual Partners as Major Predictor of Human Immunodeficiency Virus Seropositivity Among Pregnant Women, Osun State, Nigeria.

Aug 19, 2021

Concerning human immunodeficiency virus (HIV) epidemiology, pregnant women (PW) are particularly vulnerable and severely affected. Nigeria has over 40 years of HIV epidemiology and enlightenments; to ...

Discovery, optimization, and target identification of novel coumarin derivatives as HIV-1 reverse transcriptase-associated ribonuclease H inhibitors.

Aug 19, 2021

Despite significant advances in antiretroviral therapy, acquired immunodeficiency syndrome remains as one of the leading causes of death worldwide. New antiretroviral drugs combined with updated treat...

Knowledge, attitude and practices towards visceral leishmaniasis among HIV patients: A cross-sectional study from Bihar, India.

Aug 19, 2021

In the Indian state of Bihar, visceral leishmaniasis (VL) is a major public health issue that has been aggravated by the rising incidence of new Human immunodeficiency virus (HIV) infections. In endem...

CME/CE: COVID-19-Related Medical Mistrust Can Impact Inequities among Black People With HIV

Aug 16, 2021

This course discusses a study that examined a convenience sample of Black Americans who are HIV-positive or associations of COVID-19-related medical mistrust with vaccine and treatment hesitancy in Ma...

Evaluation of the Aptima HIV-1 Quant Dx assay for HIV diagnosis at birth in South Africa.

Aug 16, 2021

The increased coverage of antiretroviral therapy has resulted in a decrease in the positive predictive value (PPV) and diagnostic sensitivity of early infant diagnosis assays. To evaluate the diagnost...

Impact of dosing strategies on plasma concentrations of tenofovir: Implications in HIV pre-exposure prophylaxis in China.

Aug 16, 2021

Tenofovir disoproxil fumarate has been recommended for pre-exposure prophylaxis (PrEP) to prevent HIV infection. Several studies have shown short but potent intermittent PrEP could provide comparable ...

Bayesian multi-response nonlinear mixed-effect model: application of two recent HIV infection biomarkers.

Aug 16, 2021

Since the discovery of the human immunodeficiency virus (HIV) 35 years ago, the epidemic is still ongoing in France. To monitor the dynamics of HIV transmission and assess the impact of prevention cam...

Chemical Compounds and Computational Prediction of Their Inhibitory Effects on the HIV-1 gp120 Receptor by Lingzhi or Reishi Medicinal Mushroom, Ganoderma lucidum (Agaricomycetes), with Antler-Like Morphology of Fruiting Bodies.

Aug 12, 2021

In this study, crude extracts of Ganoderma lucidum (NGCs) were compared to the crude extracts of G. lucidum that has antler-like fruiting bodies (AGCs) for their cytotoxicity, inhibitory effects on th...

The anatomical basis for preserving the blood supply to the parathyroids during thyroid surgery, and a review of current technologic advances.

Aug 12, 2021

Devascularization of the parathyroid glands is generally accepted as the most common mechanism for iatrogenic hypocalcemia, a frequently seen complication of both total and completion thyroidectomy pr...

Gray matter volumes discriminate cognitively impaired and unimpaired people with HIV.

Aug 12, 2021

Current diagnostic criteria of HIV-associated neurocognitive disorders (HAND) rely on neuropsychological assessments. The aim of this study was to evaluate if gray matter volumes (GMV) can distinguish...

Risk factors for COVID-19-related in-hospital mortality in a high HIV and tuberculosis prevalence setting in South Africa: a cohort study.

Aug 09, 2021

The interaction between COVID-19, non-communicable diseases, and chronic infectious diseases such as HIV and tuberculosis is unclear, particularly in low-income and middle-income countries in Africa. ...

Measuring consumers' knowledge of the environmental impact of foods.

Aug 09, 2021

Our daily food choices have a huge impact on the environment. However, most consumers are not aware of the environmental impact of food production and consumption. Since there is no valid and reliable...

The human gut mycobiome and the specific role of Candida albicans: where do we stand, as clinicians?

Aug 09, 2021

The so-called "mycobiome" has progressively acquired interest and increased the complexity of the understanding of the human gut microbiota. Several questions are arising concerning the role of fungi ...

Zn-MOF decorated bio activated carbon for photocatalytic degradation, oxygen evolution and reduction catalysis.

Aug 05, 2021

An emerging global necessity for alternative resources combined with maximum catalytic efficiency, low cost, and eco-friendly composite remains a hotspot in the scientific society. Hereby, a novel pro...