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STDs

The efficacy of vaccination to prevent human papilloma viruses infection at anal and oral: a systematic review and meta-analysis.

Jul 08, 2021

The objective of this study was to review evidence on the effectiveness of vaccination in the prevention of human papilloma virus (HPV) infection at the cervix, anal, and oral.Systematic review and me...

Bicyclol ameliorates nonalcoholic fatty liver disease in mice via inhibiting MAPKs and NF-κB signaling pathways.

Jul 08, 2021

Bicyclol has been approved as an anti-inflammatory, hepatoprotective drug in China to treat various forms of hepatitis. However, the role of bicyclol in non-alcoholic fatty liver disease (NAFLD) is un...

The Effects of Hepatitis B Virus Infection on Natural and IVF Pregnancy: A Meta-analysis Study.

Jul 05, 2021

Hepatitis B Virus (HBV) has been considered a significant cause of human reproductive failure in different studies; however, there is a considerable disagreement on the true impacts of HBV on female r...

The confounding effect of multi-type human papillomavirus infections on type-specific natural history parameter identification.

Jul 05, 2021

The natural history of human papillomavirus (HPV) from infection to cervical cancer differs between HPV types. Accordingly, type-specific natural history parameters are crucial for the mathematical mo...

Woodchuck Hepatitis Virus Post-Transcriptional Regulation Element (WPRE) Promotes Anti-CD19 BiTE Expression in Expi293 Cells.

Jul 05, 2021

Bispecific antibodies represent an important class of monoclonal antibodies (mAbs), with great therapeutic potentials due to their ability to target simultaneously two distinct epitopes. The generatio...

The 2019 HPV Labnet international proficiency study: Need of global Human Papillomavirus Proficiency Testing.

Jul 01, 2021

Accurate and internationally comparable human papillomavirus (HPV) testing services are essential for cervical cancer elimination programs. The WHO HPV Laboratory Network started issuing international...

ACUTE LIVER FAILURE REQUIRING TRANSPLANTATION: A POSSIBLE LINK TO ULIPRISTAL ACETATE TREATMENT?

Jul 01, 2021

The present case describes in detail a 55-year-old woman diagnosed with acute liver injury 3 days after completion of the first treatment course with ulipristal acetate (UPA), 5 mg/day orally for uter...

IDENTIFICATION OF OPTIMAL THERAPEUTIC WINDOW FOR STEROID USE IN SEVERE ALCOHOL-ASSOCIATED HEPATITIS: A WORLDWIDE STUDY.

Jun 28, 2021

Corticosteroids are the only effective therapy for severe alcohol-associated hepatitis (AH), defined as MELD score >20. However, there are patients who may be too sick to benefit from therapy.To id...

Ameliorating effect on glycolipid metabolism and chemical profile of Millettia speciosa champ. extract.

Jun 28, 2021

Millettia speciosa Champ., also called Niu dali, is a fabaceous medicinal plant mainly distributed in southeast China, where it is a functional food for developing physical strength, and often used tr...

Seroprevalence of Chlamydia trachomatis, herpes simplex 2, Epstein-Barr virus, hepatitis C and associated factors among a cohort of men ages 18-70 years from three countries.

Jun 24, 2021

To estimate the seroprevalence of Chlamydia trachomatis (CT), herpes simplex type-2 (HSV2), hepatitis C (HCV), Epstein-Barr virus (EBV) and nine human papilloma virus (HPV) types, and investigated fac...

Association of central obesity with hepatocellular carcinoma in patients with chronic hepatitis B receiving antiviral therapy.

Jun 24, 2021

Obesity is typically associated with metabolic dysfunction, but its impact on hepatocellular carcinoma (HCC) remains unclear in patients with chronic hepatitis B (CHB).To study the effect of obesity o...

Age-dependence of hypervirulent fowl adenovirus type 4 pathogenicity in specific-pathogen-free chickens.

Jun 24, 2021

Hypervirulent fowl adenovirus serotype 4 (hvFAdV-4) has emerged as a major pathogen of hepatitis-hydropericardium syndrome (HHS) with increased mortality in chickens, resulting in economic losses to t...

[Unusual cause of a PCT-elevation].

Jun 17, 2021

 Procalcitonin (PCT) is an established marker for bacterial infection. Elevation of PCT can occur due to various reasons and is not specific, as we outline in the following case report. We report ...

Interleukin-17 in Liver Disease Pathogenesis.

Jun 17, 2021

Interleukin 17A (IL-17A)-producing T helper 17 (Th17) cells were identified as a subset of T helper cells that play a critical role in host defense against bacterial and fungal pathogens. Th17 cells d...

Extended-release naltrexone for youth with opioid use disorder.

Jun 14, 2021

Few published research studies have examined the effectiveness of extended-release naltrexone (XR-NTX) for the treatment of opioid use disorder (OUD) among adolescents and young adults.This two-group ...

Feasibility and early experience of a novel multidisciplinary alcohol-associated liver disease clinic.

Jun 14, 2021

Alcohol cessation improves mortality in alcohol-associated liver disease (ALD), but access to treatment is limited. To address this gap, implementation and early feasibility and outcomes of a multidis...

Trends in serological markers of transfusion transmissible infections in blood donations at the Bamenda Hospital-based Blood Service, Cameroon.

Jun 10, 2021

The rate and trend of transfusion transmissible infections (TTIs) in blood donations from 2012 to 2017 at the Bamenda Regional Hospital Blood Service (BRHBS), Cameroon was assessed.A six-year retrospe...

Impact of TLR7 and TLR9 polymorphisms on susceptibility to placental infections and pregnancy complications.

Jun 10, 2021

This study evaluated the impact of the TLR7 Gln11Leu (rs179008) and TLR9 -1237 T/C (rs5743836) single nucleotide polymorphisms (SNPs) on susceptibility to placental infections and pregnancy complica...

Identification of brevinin-1EMa-derived stapled peptides as broad-spectrum virus entry blockers.

Jun 07, 2021

Based on the previously reported 13-residue antibacterial peptide analog, brevinin-1EMa (FLGWLFKVASKVL, peptide B), we attempted to design a novel class of antiviral peptides. For this goal, we synthe...

Fluorescent paper-based DNA sensor using pyrrolidinyl peptide nucleic acids for hepatitis C virus detection.

Jun 07, 2021

A novel fluorescent paper-based DNA sensor employing a highly specific pyrrolidinyl peptide nucleic acid (acpcPNA) probe was developed for the sensitive and selective detection of hepatitis C virus (H...