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Vaccines

Assessing Pediatric Immunization Practices in Nephrotic Syndrome

May 10, 2021

In the current era of the COVID-19 pandemic, understanding barriers to vaccinations in immunosuppressed children has become more crucial than ever, according to Cheryl L. Train, MD. “Children with n...

Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled trial.

May 10, 2021

Stalled progress in controlling Plasmodium falciparum malaria highlights the need for an effective and deployable vaccine. RTS,S/AS01, the most effective malaria vaccine candidate to date, demonstrate...

Nasal vaccination against SARS-CoV-2: synergistic or alternative to intramuscular vaccines?

May 10, 2021

It is striking that all marketed SARS-CoV-2 vaccines are developed for intramuscular administration designed to produce humoral and cell mediated immune responses, preventing viremia and the COVID-19 ...

Effects of a combination of Mass and Dutch variant as an inactivated vaccine against variant 2 avian infectious bronchitis virus challenge.

May 10, 2021

The present study aimed to evaluate the effects of inactivated vaccines combining Mass and Dutch variants as vaccine boosters after H120 priming on inhibiting variant 2 viral load in the kidneys (as t...

Molecular characterization and protective efficacy of a new conserved hypothetical protein of Eimeria tenella.

May 06, 2021

Eimeria tenella is an obligate intracellular parasite that actively invades cecal epithelial cells of chickens. This parasite encodes a genome of more than 8000 genes. However, more than 70% of the ge...

Long-term immunity and the effect of one or two booster doses with a lyophilized human rabies vaccine (human diploid cells) at 10 years post primary vaccination in China.

May 06, 2021

To evaluate the persistence of antibody for 10 years, and investigate the effect of one or two booster doses with Kanghua human diploid cells rabies vaccine (HDCV) in China. Participants were re-rec...

SARS-CoV-2 vaccine and thrombosis: Expert opinions.

May 06, 2021

Historically, the vaccination strategies developed in the second half of the 20th century have permitted to eradicate infectious diseases. From the onset of COVID-19 pandemic to March 2021, more than ...

miR-451a levels rather than human papillomavirus vaccine administration is associated with the severity of murine experimental autoimmune encephalomyelitis.

May 03, 2021

Human papilloma virus (HPV) vaccine is currently the most effective prophylaxis to prevent cervical cancer. However, concerns regarding its potential severe adverse reactions have limited the vaccinat...

Vaccine-induced prothrombotic immune thrombocytopenia (VIPIT): Consider IVIG batch in the treatment.

May 03, 2021

Various vaccines have been developed recently to protect the population from corona virus disease-19 (COVID-19). Although the beneficial effects of vaccines outweigh the risks associated with vaccinat...

Brief review of the mRNA vaccines COVID-19.

May 03, 2021

The global COVID-19 pandemic continues to claim victims worldwide, representing a health and socioeconomic challenge with few precedents in human history. The therapeutic agents used to treat COVID-19...

Willingness to vaccinate against COVID-19 among Bangladeshi adults: Understanding the strategies to optimize vaccination coverage.

Apr 29, 2021

Although the approved COVID-19 vaccine has been shown to be safe and effective, mass vaccination in Bangladeshi people remains a challenge. As a vaccination effort, the study provided an empirical evi...

COVID-19 vaccine hesitancy in perinatal women: a cross sectional survey.

Apr 29, 2021

To explore attitudes to COVID-19 vaccination among perinatal women.A nationwide online, cross-sectional survey was conducted in Qatar from 15th October 2020 to 15th November 2020 with voluntary partic...

Age-dependent immune response to the Biontech/Pfizer BNT162b2 COVID-19 vaccination.

Apr 29, 2021

The SARS-CoV-2 pandemic has led to the development of various vaccines. Real-life data on immune responses elicited in the most vulnerable group of vaccinees over 80 years old is still underrepresente...

COVID-19-Related Medical Mistrust Can Impact Inequities among Black People With HIV

Apr 26, 2021

Medical mistrust among Black Americans, resulting from systemic racism and a history of unequal treatment in healthcare, may play a role in COVID-19 inequities, specifically among Black Americans livi...

Covid-19 mRNA Vaccination: Age and Immune Status and its Association with Axillary Lymph Node PET/CT Uptake.

Apr 26, 2021

With hundreds of millions of coronavirus disease 2019 (COVID-19) mRNA-based vaccine doses planned to be delivered worldwide in the upcoming months, it is important to recognize positron emission tomog...

Global prevalence and phylogeny of hepatitis B virus (HBV) drug and vaccine resistance mutations.

Apr 26, 2021

Vaccination and anti-viral therapy with nucleos(t)ide analogues (NAs) are key approaches to reducing the morbidity, mortality and transmission of hepatitis B virus (HBV) infection. However, the effica...

Immediate Bacille Calmette-Guérin vaccination to neonates requiring perinatal treatment at the maternity ward in Guinea-Bissau: A randomized controlled trial.

Apr 26, 2021

Randomized controlled trials (RCTs) indicate that Bacille Calmette-Guérin (BCG) vaccination provides broad beneficial non-specific protection against infections. We investigated the effect on in-hosp...

Vaccine Hesitancy: Assessing Challenges and Recommendations

Apr 22, 2021

Vaccination hesitancy typically originates from concerns about the safety and efficacy of vaccines and from a lack of trust in institutions that promote vaccines, according to Lavanya Vasudevan, PhD, ...

Interrupted time-series analyses of routine vaccination program for elderly pneumonia patients in Japan; an ecological study using aggregated nationwide inpatient data.

Apr 22, 2021

A national routine pneumococcal pneumonia immunization program started in Japan in 2014. It targeted the population aged ≥65 years and used a 23-valent pneumococcal polysaccharide vaccine; PPSV23....

Multifaceted strategies for the control of COVID-19 outbreaks in long-term care facilities in Ontario, Canada.

Apr 22, 2021

The novel coronavirus disease 2019 (COVID-19) has caused severe outbreaks in Canadian long-term care facilities (LTCFs). In Canada, over 80% of COVID-19 deaths during the first pandemic wave occurred ...