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CKD

Examining the Mental Health Needs of Adults With Self-Reported CKD

Aug 18, 2022

Data indicate that patients with chronic kidney disease (CKD) and comorbid mental illnesses have higher risks of death and hospitalization and a more rapid progression toward kidney failure than those...

Racial Disparity Seen in Healthcare Among Blacks With CKD

Jul 11, 2022

When encountering racism, Black veterans with chronic kidney disease described bottling up their feelings, which sometimes led to maladaptive behaviors. Several factors have been associated wit...

High CKD Burden in Patients & Their Care Partners

Jun 30, 2022

CKD impacts multiple dimensions of patients and care partners’ lives, including HRQOL, work productivity, and care received/provided. Among the many disabling complications associated with CK...

Screen Early to Prevent CKD and Mitigate Chronic Conditions

May 24, 2022

Currently, about 37 million adults across the United States are living with chronic kidney disease (CKD). By the CDC’s estimate, this is about 15% of all adults in the country. Yet, by that same est...

Comparative Study to Evaluate the Effect of Low-Protein Diet Supplementation with Taurine and N-Acetylcysteine, N-Acetylcysteine and Pyridoxamine Dihydrochloride in Preventing the Progression of Chronic Renal Failure in Patients with Non-Diabetic Kidney Disease.

May 23, 2022

Chronic Kidney Disease(CKD) has multifactorial etiology and there are lots of grey zone in understanding its complex pathophysiology. There is no silver bullet for optimal care of CKD. Oxidative stres...

Retino-Renal Dissociation in Type 2 Diabetes Mellitus: An Observational Cross Sectional Study at a Tertiary Care Center of Sub-Himalayan Region.

May 23, 2022

Diabetic retinopathy, the diabetes-specific long-term microvascular complication is an important predictor of diabetic nephropathy. Diabetes induced retinopathy mostly proceeds nephropathy in patients...

Clinical characteristics and disease outcomes in non-diabetic chronic kidney disease: retrospective analysis of a US healthcare claims database.

May 16, 2022

The observational, real-world evidence FLIEDER study aimed to describe patient clinical characteristics and investigate clinical outcomes in non-diabetic patients with chronic kidney disease (CKD) usi...

Microparticles in Diabetic Kidney Disease.

May 16, 2022

Diabetickidneydisease(DKD)isthemostcommoncauseofrenal failure and a major contributor to the socioeconomic burden in chronic kidney disease (CKD) patients worldwide. The pathogenesis of DKD involves a...

Implementing a resistance training programme for patients on short daily haemodialysis: A feasibility study.

May 09, 2022

Kidney failure patients receiving haemodialysis experience protein-energy wasting, muscle mass loss and physical function impairment. Intradialytic exercise interventions seem to modify these feature...

Psychosocial factors in patients with kidney failure and role for social worker: A secondary data audit.

May 09, 2022

People with kidney failure face a multitude of psychosocial stressors that affect disease trajectory and health outcomes.To investigate psychosocial factors affecting people with kidney failure before...

Genetics in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Apr 25, 2022

Numerous genes for monogenic kidney diseases with classical patterns of inheritance, as well as genes for complex kidney diseases that manifest in combination with environmental factors, have been dis...

Prognosis of Chronic Kidney Disease in Patients with Non-Alcoholic Fatty Liver Disease: a Northeastern Taiwan Community Medicine Research Cohort.

Apr 25, 2022

Non-alcoholic fatty liver disease (NAFLD) is associated with incident chronic kidney disease (CKD). We aimed to investigate outcomes and risk factors of CKD progression and regression.This is a longit...

Ginsenoside Rg1 attenuates LPS-induced chronic renal injury by inhibiting NOX4-NLRP3 signaling in mice.

Apr 18, 2022

Chronic renal injury (CRI) is a common pathological damage in chronic renal disease, and the therapeutic options for preventing its progression are limited at present. Ginsenoside Rg1 (Rg1) is reporte...

#VisualAbstract: Daprodustat noninferior to darbepoetin alfa in the treatment of anemia in patients with chronic kidney disease on incident dialysis

Apr 15, 2022

1. This trial demonstrated noninferiority of daprodustat to darbepoetin alfa in the treatment of anemia in patients with chronic kidney disease starting incident analysis. 2. The safety profile...

CUX1 promotes epithelial-mesenchymal transition (EMT) in renal fibrosis of UUO model by targeting MMP7.

Apr 11, 2022

Epithelial-to-mesenchymal transition (EMT) displays a critical role in the development of renal fibrosis, an important pathological process of chronic kidney disease (CKD). Transcription factor Cut-li...

Novel insights into NOD-like receptors in renal diseases.

Apr 04, 2022

Nucleotide-binding oligomerization domain-like receptors (NLRs), including NLRAs, NLRBs (also known as NAIPs), NLRCs, and NLRPs, are a major subfamily of pattern recognition receptors (PRRs). Owing to...

Examining Risk for CKD Progression & Kidney Failure Post-Nephrectomy

Mar 30, 2022

“Whether chronic kidney disease (CKD) due to surgical removal of kidney tissue (nephrectomy) is as significant as CKD due to other etiologies remains unclear,” explains Robert J. Ellis, MD, PhD. ...

Experiences of a cognitive behavioural therapy (CBT) intervention for fatigue in patients receiving haemodialysis.

Mar 28, 2022

A feasibility randomised-controlled trial found that a cognitive-behavioural therapy intervention for renal fatigue has the potential to reduce fatigue in patients receiving haemodialysis, but uptak...

Targeted inhibition of ZAK ameliorates renal interstitial fibrosis.

Mar 14, 2022

ZAK (sterile alpha motif and leucine zipper-containing kinase) is a newly discovered member of the subfamily of mitogen-activated protein kinase kinase kinases (MAP3Ks). The role of ZAK in kidney dise...

Construction and evaluation of an integrated predictive model for chronic kidney disease based on the random forest and artificial neural network approaches.

Mar 14, 2022

Chronic kidney disease (CKD) is recognized as a serious global health problem due to its high prevalence and all-cause mortality. The aim of this research was to identify critical biomarkers and const...