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Congestive Heart Failure

IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.

Nov 16, 2020

Previous reports indicate IL18 is a novel candidate gene for diastolic dysfunction in sickle cell disease (SCD)-related cardiomyopathy. We hypothesize that IL-18 mediates the development of cardiomyop...

Impaired repolarization parameters may predict fatal ventricular arrhythmias in patients with hypertrophic cardiomyopathy (from the CILICIA Registry).

Nov 05, 2020

Hypertrophic cardiomyopathy (HCM) is significantly associated with high risk of fatal ventricular arrhythmias (VAs). Increased frontal QRST angle (fQRSTa), Tpe interval, and Tp-e/QTc ratio are describ...

Attitudes of Dilated Cardiomyopathy Patients and Investigators Toward Genomic Study Enrollment, Consent Process, and Return of Genetic Results.

Oct 29, 2020

Precision medicine genetics study design requires large, diverse cohorts and thoughtful use of electronic technologies. Involving patients in research design may increase enrollment and engagement, th...

Non-heart transplant surgical approaches with mitral valve operation and surgical ventricular reconstruction for non-ischaemic dilated cardiomyopathy: a Japanese multicenter study.

Oct 26, 2020

There is uncertainty over the efficacy of additional surgical ventricular reconstruction (SVR) associated with mitral valve operation for non-ischaemic dilated cardiomyopathy (DCM). This study aims to...

Results from an Epidemiological Follow-Up Survey on Home Artificial Nutrition in Switzerland from 2010 to 2015.

Oct 22, 2020

Home artificial nutrition (HAN) is an established treatment for malnourished patients. Since July 2012, the costs for oral nutrition supplements (ONS) are covered by the compulsory health insurance pr...

Genetic Spectrum of Left Ventricular Non-Compaction in Paediatric Patients.

Oct 15, 2020

Left ventricular non-compaction (LVNC) represents a genetically heterogeneous cardiomyopathy which occurs in both children and adults. Its genetic spectrum overlaps with other types of cardiomyopathy....

Precision-optimized single protocol pre-/post-contrast modified-look locker inversion T1 mapping using composite inversion group fitting.

Oct 05, 2020

Investigation of a simple, precision optimized, identical pre-/post-contrast modified look locker inversion recovery (MOLLI) protocol employing Composite inversion group (IG) fitting in a clinical car...

Large Vessel Occlusion Secondary to COVID-19 Hypercoagulability in a Young Patient: A Case Report and Literature Review.

Oct 01, 2020

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) initially most appreciated for its pulmonary symptoms, is now increasingly recognized for causing multi-organ disease and stroke in the set...

Relationship between the cardiac magnetic resonance derived extracellular volume fraction and feature tracking myocardial strain in patients with non-ischemic dilated cardiomyopathy.

Sep 10, 2020

Feature tracking (FT) has emerged as a promising method to quantify myocardial strain using conventional cine magnetic resonance imaging (MRI). Extracellular volume fraction (ECV) by T1 mapping enable...

Luteolin supplementation ameliorates cobalt-induced oxidative stress and inflammation by suppressing NF-кB/Kim-1 signaling in the heart and kidney of rats.

Sep 10, 2020

Cobalt-induced cardiomyopathy and renal toxicity have been reported in workers in processing plants, hard metal industries, diamond polishing and manufacture of ceramics. This study was designed to in...

Identifying low-risk chest pain in the emergency department: Obstructive coronary artery disease and major adverse cardiac events.

Aug 03, 2020

Accurate risk stratification for obstructive coronary artery disease (CAD) and major cardiac adverse events (MACE) is important in emergency departments. We compared six established chest pain risk sc...

Investigation on protective effect of Terminalia bellirica (Roxb.) against drugs induced cardiotoxicity in wistar albino rats.

Jun 15, 2020

Various traditional texts like Ayurveda and Materia Medica profoundly mentioned the ethnopharmacological use of Terminalia bellirica fruit for its protective effect on heart and various other vital or...

An assessment of the role of vinculin (VCL) loss of function variants in inherited cardiomyopathy.

Jun 11, 2020

The ACMG/AMP variant classification framework was intended for highly penetrant Mendelian conditions. While it is appreciated that clinically relevant variants exhibit a wide spectrum of penetrance, a...

Environmental Chemical Exposure Tied to Kidney Disease in the U.S.

May 26, 2020

TUESDAY, May 26, 2020 (HealthDay News) -- Increased exposure to heavy metal lead, cadmium, or volatile organic compounds may be associated with an increased prevalence of chronic kidney disease (CKD),...

Chronic Kidney Disease & Cardiac Biomarkers

May 15, 2020

Previous studies have established a direct association between chronic kidney disease (CKD) and cardiovascular (CV) mortality and morbidity. Evidence suggests that patients with CKD have an increased ...

Acute Kidney Injury Seems to Promote Renal Cell Carcinoma

Apr 07, 2020

THURSDAY, March 26, 2020 (HealthDay News) -- Acute kidney injury (AKI) seems to promote the development of papillary renal cell carcinoma (pRCC) from single progenitors, according to a study published...

Chronic Kidney Disease Linked to Uncontrolled Blood Pressure

Apr 06, 2020

MONDAY, March 30, 2020 (HealthDay News) -- Chronic kidney disease (CKD) is associated with uncontrolled blood pressure (BP), while ambulatory BP patterns are not associated with cognitive impairment o...

Social Support & ESRD Treatment Adherence

Mar 25, 2020

Although patients with end-stage renal disease (ESRD) cannot survive without lifelong renal replacement treatment, such as dialysis and renal transplantation, these highly demanding treatments involve...

Statement Addresses Concerns About Heart Meds and COVID-19

Mar 22, 2020

Patients advised to continue ACE inhibitors/ARBs after researcher posits risk for severe COVID-19 infection FRIDAY, March 20, 2020 (HealthDay News) -- Patients already prescribed angiotensin-conv...

Digestive Symptoms Reported for About Half of COVID-19 Patients

Mar 19, 2020

THURSDAY, March 19, 2020 (HealthDay News) -- Patients with coronavirus 2019 (COVID-19) frequently have digestive symptoms, and those with digestive symptoms have a worse clinical outcome, according to...