APOL1 at ten years: Progress and next steps.

APOL1 kidney risk variants (RVs) were identified in 2010 as major drivers of glomerular, tubulointerstitial and renal microvascular disease in individuals with sub-Saharan African ancestry. In December 2020, the “APOL1 at...

From Kidney Injury to Kidney Cancer.

Epidemiological studies document strong associations between acute or chronic kidney injury and kidney tumors. However, whether these associations are linked by causation, and in which direction, is unclear. Accumulating data...