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Neurology

Long Non-Coding RNAs BACE1-AS and BC200 in Multiple Sclerosis and their Relation to Cognitive function: A Gene Expression Analysis.

May 29, 2023

Cognitive impairment is a common and debilitating feature of multiple sclerosis (MS), and the dysregulation of synaptic plasticity is one of its direct causes. Long non-coding RNAs (lncRNAs) have been...

Neuroprotection in cerebral cortex induced by the pregnancy hormone estriol.

May 29, 2023

In multiple sclerosis (MS), demyelination occurs in cerebral cortex, and cerebral cortex atrophy correlates with clinical disabilities. Treatments are needed in MS to induce remyelination. Pregnancy i...

Migraine Treatment Using Erenumab: Can Lead to a Cognitive and Psychological Qualitative Improvement?

May 29, 2023

Migraine is one of the most disabling disorders in the world, associated with poor quality of life. Migraine prevention strategies have increasingly evolved since monoclonal antibodies against the cal...

Integrating eQTL and GWAS data characterises established and identifies novel migraine risk loci.

May 29, 2023

Migraine-a painful, throbbing headache disorder-is the most common complex brain disorder, yet its molecular mechanisms remain unclear. Genome-wide association studies (GWAS) have proven successful in...

Investigation of brain mechanisms underlying upper limb function in bilateral cerebral palsy using EEG.

May 29, 2023

Few studies focus on upper limbs in bilateral cerebral palsy (CP) despite potential bimanual deficits. Electroencephalography (EEG) was utilized to investigate brain mechanisms underlying upper limb t...

Effectiveness of land- and water-based exercise on fatigue and sleep quality in women with fibromyalgia: the al-Ándalus quasi-experimental study.

May 29, 2023

To assess the effectiveness of 24 weeks of land- and water-based exercise on fatigue and sleep quality in women with fibromyalgia, and the persistence of changes 12 weeks after exercise cessation.quas...

Targeting α7-nAChR by galantamine mitigates reserpine-induced fibromyalgia-like symptoms in rats: Involvement of cAMP/PKA, PI3K/AKT, and M1/M2 microglia polarization.

May 29, 2023

Fibromyalgia (FM) is a pain disorder marked by generalized musculoskeletal pain accompanied by depression, fatigue, and sleep disturbances. Galantamine (Gal) is a positive allosteric modulator of neur...

Assessing farmer's exposure to pesticides and the risk for non-communicable diseases: A biomonitoring study.

May 29, 2023

This cross-sectional study aimed to assess the adverse effects of pesticide use in humans, such as non-communicable diseases, using acetylcholinesterase (AChE) and pesticide concentrations in blood sa...

Effectiveness and safety of anticoagulants among venous thromboembolism cancer patients with and without brain cancer.

May 29, 2023

Patients with brain cancer are at a high risk of developing venous thromboembolism (VTE) and are underrepresented in clinical trials. This study compared the risk of recurrent VTE (rVTE), major bleedi...

Functional connectivity of cortical-cerebellar networks in relation to sensorimotor behavior and clinical features in autism spectrum disorder.

May 29, 2023

Sensorimotor issues are present in the majority of individuals with autism spectrum disorder (ASD) and are associated with core symptoms. The neural systems associated with these impairments remain un...

A Multicentre, Randomised, Open-Label, Prospective Study to Estimate the Add-On Effects Of Memantine as Ebixa Oral Pump (Solution) on Language in Patients with Moderate to Severe Alzheimer's Disease Already Receiving Donepezil (ROMEO-AD).

May 29, 2023

This multicentre, randomised, open-label, and prospective study aimed to evaluate the effectiveness of memantine (memantine solution) on speech function in patients with moderate to severe Alzheimer's...

Effects of agricultural land types on microplastic abundance: A nationwide meta-analysis in China.

May 29, 2023

Microplastics (MPs) accumulation in agricultural land that possibly poses threats to food security and human health has recently attracted increasing attention. Land use type probably is a key factor ...

Multiple Concussions in Youth Tied to Variety of Greater Symptoms

May 27, 2023

FRIDAY, May 26, 2023 (HealthDay News) -- Young patients with a history of multiple concussions report greater cognitive, sleep, and neuropsychiatric symptoms than those with one prior head injury, acc...

Higher Poststroke Glucose Levels Tied to Faster Cognitive Decline

May 27, 2023

FRIDAY, May 26, 2023 (HealthDay News) -- Higher poststroke glucose levels are associated with faster subsequent global cognitive decline, according to research published online May 17 in JAMA Network ...

Elon Musk's Neuralink Says Brain-to-Computer Interface Has FDA Approval for Clinical Trial

May 27, 2023

FRIDAY, May 26, 2023 (HealthDay News) -- It may sound like the stuff of science fiction, but Elon Musk's company Neuralink announced Thursday that the U.S. Food and Drug Administration has approved a ...

Multivitamin Shows Memory Benefits in Older Adults

May 27, 2023

FRIDAY, May 26, 2023 (HealthDay News) -- Daily multivitamin supplementation improves memory in older adults compared with placebo, according to a study published online May 24 in the American Journal ...

Efficacy of Anterior Nucleus of the Thalamus Deep Brain Stimulation in Drug-resistant Epilepsy

May 26, 2023

The following is a summary of "Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Drug-Resistant Epilepsy in the MORE Multicenter Patient Registry," published in the May 02, 2023 issue ...

Causal Link ID'd for Alzheimer Disease, Generalized Epilepsy

May 25, 2023

THURSDAY, May 25, 2023 (HealthDay News) -- There is a causal link between Alzheimer disease (AD), amyloid pathology, and generalized epilepsy, according to a study published online May 24 in Neurology...

Examining Cognitive and Clinical Features of Individuals Affected by LATE

May 25, 2023

The following is a summary of "Cognitive and Clinical Characteristics of Patients With Limbic-Predominant Age-Related TDP-43 Encephalopathy," published in the May 2023 issue of Neurology by Pagnotti, ...

More Older Americans Use Online Patient Portals to Access Care

May 24, 2023

WEDNESDAY, May 24, 2023 (HealthDay News) -- Older Americans are increasingly likely to log into patient portals to access their health care information -- but confidence levels vary, according to the ...