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Pain Management

Effects of melatonin administration on testicular hemodynamics, echotexture, steroids production, and semen parameters during the non-breeding season in Ossimi rams.

Mar 14, 2022

This study was conducted to determine the influence of a single subcutaneous (SC) injection of melatonin (18 and 36 mg) on testicular hemodynamics, echotexture, plasma testosterone concentration, and...

Measuring Clinically Meaningful Change in Outcomes for Youth with Chronic Pain Following Graded Exposure Treatment.

Mar 14, 2022

Functional improvement is a critical outcome for individuals living with chronic pain. Graded exposure treatment has been associated with statistically significant improvements in functional outcomes ...

Deep Pelvic Side Wall Anatomy; A Case of Laparoscopic Management of Vaginal Vault Fistula to the Presacral Area.

Mar 07, 2022

Video presentation showing retroperitoneal dissection and deep pelvic side wall anatomy.Case presentation with showing anatomical structures in detail.Tertiary academic teaching hospital.74 year-old f...

Schnurri-2 promotes the expression of excitatory glutamate receptors and contributes to neuropathic pain.

Feb 28, 2022

Neuropathic pain is a type of chronic pain with complex mechanisms, and current treatments have shown limited success in treating patients suffering from chronic pain. Accumulating evidence has shown ...

The perceptions, needs and preferences of informal caregivers of nursing home residents with dementia regarding physical therapy: A qualitative study.

Feb 21, 2022

Informal caregivers often support nursing home residents with dementia in making therapeutic decisions. We explored the perceptions, needs and preferences of informal caregivers of nursing home reside...

Inhibition of pan-Aurora kinase attenuates evoked and ongoing pain in nerve injured rats via regulating KIF17-NR2B mediated signaling.

Feb 21, 2022

Kinesins (KIF's) are the motor proteins which are recently reported to be involved in the trafficking of nociceptors leading to chronic pain. Aurora kinases are known to be involved in the regulation ...

Simultaneous detection of 93 anabolic androgenic steroids in dietary supplements using gas chromatography tandem mass spectrometry.

Feb 07, 2022

In recent years, anabolic androgenic steroids (AASs) have been frequently detected as undeclared ingredients in dietary supplements, where the adverse analytical findings (AAFs) were obtained from ana...

Associations between pain and physical activity among older adults.

Jan 31, 2022

Chronic pain is a significant societal problem and pain complaints are one of the main causes of work absenteeism and emergency room visits. Physical activity has been associated with reduced risk of ...

Psychosocial and psychophysical assessment in pediatric patients and young adults with chronic back pain: a cluster analysis.

Jan 31, 2022

Identifying subgroups with different clinical profiles may inform tailored management and improve outcomes. The objective of this study was to identify psychosocial and psychophysical profiles of chil...

Classical prescription Dachuanxiong Formula delays nitroglycerin-induced pain response in migraine mice through reducing endothelin-1 level and regulating fatty acid biosynthesis.

Jan 17, 2022

Dachuanxiong Formula (DCXF) is a classical Chinese medicine prescription and is composed of dried rhizomes from Ligusticum striatum DC. (Chuanxiong Rhizoma) and Gastrodia elata Bl. (Gastrodiae Rhizoma...

Education level is a strong determinant of cognitive function as measured by MoCA in people with chronic low back pain.

Jan 17, 2022

Over recent years there has been increasing clinical interest in the relationship between chronic pain and cognitive function. There are very few studies on individuals with low back pain (LBP) in the...

Steroid hormones in hair and fresh wounds reveal sex specific costs of reproductive engagement and reproductive success in wild house mice (Mus musculus domesticus).

Jan 10, 2022

Not only males but also females compete over reproduction. In a population of free-living house mice (Mus musculus domesticus), we analyzed how (metabolic) costs of aggressive interactions (reflected ...

Evidence for Rehabilitation Interventions After Acute Lateral Ankle Sprains in Athletes: A Scoping Review.

Jan 03, 2022

Acute lateral ankle sprain (LAS) is a common injury in athletes and is often associated with decreased athletic performance and, if treated poorly, can result in chronic ankle issues, such as instabil...

Novel electrochemiluminescent assay for the aptamer-based detection of testosterone.

Dec 27, 2021

This work presents a proof-of-concept assay for the detection and quantification of small molecules based on aptamer recognition and electrochemiluminescence (ECL) readout. The testosterone-binding (T...

The therapeutic effect of bromocriptine as mesylate and estradiol valerate on serum and blood biochemistry of common quails.

Dec 27, 2021

Hematology and serum biochemistry study may provide antique knowledge about the physical status of individuals, making them a valuable tool to differentiate healthy animals from affected animals. We a...

Tracking Assessment Tool Supports Treatment of Opioid Use Disorder in Primary Care

Dec 21, 2021

Despite efforts to curb opioid use disorder (OUD), the epidemic continues to be a major national crisis. Methadone, buprenorphine, and naltrexone are standard of care FDA-approved treatments for OUD, ...

Local immunosuppression in WZS-pig to rhesus monkey Descemet's stripping automated endothelial keratoplasty: An innovative method to promote the survival of xeno-grafts.

Dec 20, 2021

Corneal xenotransplantation is an effective solution for the shortage of human corneas. We investigated the feasibility and efficacy of different postoperative protocols on xeno-Descemet's stripping a...

The efficacy and safety of traditional Chinese medicine Guilu Erxian Jiao in the treatment of knee osteoarthritis: A systematic review and meta-analysis.

Nov 29, 2021

A systematic review was conducted to investigate the efficacy of Guilu Erxian Jiao (GEJ) in the treatment of knee osteoarthritis (OA).We searched PubMed, MEDLINE, EMBASE, the Cochrane Central Register...

A positive association of larval therapy and hyperbaric oxygen therapy in veterinary wound care.

Nov 22, 2021

The treatment of cutaneous wounds is part of the veterinary routine from initial scientific reports due to being regularly present condition. Currently, several types of treatments are available to ac...

Perampanel may represent an effective treatment for the prevention of migraine comorbid with epilepsy.

Nov 08, 2021

Migraine is a common comorbidity in patients with epilepsy. Considering the proven associations and the common pathophysiological features linking epilepsy and migraine, some anti-seizure medications ...