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Sleep Disorders

Improving Sleep Patterns May Prevent Cardiovascular Disease Progression

Jan 05, 2024

Researchers examining sleep patterns observe a varied and complex progression of cardiac deterioration from baseline health to first cardiovascular disease. The complexity of sleep in terms of ...

#VisualAbstract: Pharmacotherapy Is Effective for Acute Insomnia But With Worse Side Effect Profiles Than Placebo

Aug 11, 2022

1. Eszopiclone and Lemborexant were more efficacious for acute and long-term insomnia compared to placebo but were associated with more dropouts due to adverse events compared to placebo. 2. In...

Exploring OSA & Weight Loss in Adults Attending Weight Management Program

Feb 16, 2022

Class 3 obesity—defined as a BMI higher than 40 kg/m2—is associated with an increased incidence of hypertension, T2D, heart disease, and obstructive sleep apnea (OSA). “There is an increasing nu...

Screening for Primary Aldosteronism is Underutilized in Patients with Obstructive Sleep Apnea.

Sep 13, 2021

Resistant hypertension is common in patients with primary aldosteronism and in those with obstructive sleep apnea. Primary aldosteronism treatment improves sleep apnea. Despite Endocrine Society guide...

Application of personalized medicine to obstructive sleep apnea in China.

Sep 13, 2021

Obstructive sleep apnea (OSA) is a common sleep disorder whose prevalence is increasing in China consistent with rising obesity trends. OSA is a heterogeneous disorder depends on anatomical and nonana...

Insomnia, anxiety, and depression during the COVID-19 pandemic: an international collaborative study.

Sep 13, 2021

The COVID-19 pandemic has produced unprecedented changes in social, work, and leisure activities, which all have had major impact on sleep and psychological well-being. This study documented the preva...

Periodic limb movements during sleep are associated with poor health-related quality of life in patients with obstructive sleep apnea.

Aug 19, 2021

The clinical significance of the comorbidity of periodic limb movements during sleep (PLMS) in sleep-disordered breathing remains unclear. This study aimed to determine whether or not the presence of ...

Paradoxical intention for insomnia: A systematic review and meta-analysis.

Aug 19, 2021

Paradoxical intention (PI) has been considered an evidence-based treatment for insomnia since the 1990s, but it has not been evaluated with modern review techniques such as meta-analysis. The present ...

Targeting Depressive Symptoms in Younger Breast Cancer Survivors: The Pathways to Wellness Randomized Controlled Trial of Mindfulness Meditation and Survivorship Education.

Aug 19, 2021

Younger women are at risk for depression and related symptoms following breast cancer. The Pathways to Wellness study, a randomized, multi-institution, three-arm trial, tested the efficacy of two beha...

Characteristics of Cancer-Related Fatigue and Concomitant Sleep Disturbance in Cancer Patients.

Aug 05, 2021

Cancer patients often experience cancer-related fatigue (CRF) and sleep disturbances due to cancer and cancer treatment, and symptoms can persist long after treatment. Despite these common occurrences...

Obstructive sleep apnea and risk of motor vehicle accident.

Aug 05, 2021

To evaluate the association between obstructive sleep apnea (OSA) and risk of motor vehicle accident (MVA).We conducted a cohort study at Kaiser Permanente Washington using electronic health plan data...

Prevalence and risk factors for mental health symptoms in community epidemic prevention workers during the postpandemic era of COVID-19 in China.

Aug 05, 2021

Few people have paid attention to community epidemic prevention workers in the postpandemic era of COVID-19. This study aimed to explore the prevalence and risk factors for mental health symptoms in c...

Transcutaneous Auricular Vagus Nerve Stimulation Combined With Slow Breathing: Speculations on Potential Applications and Technical Considerations.

Jun 24, 2021

Transcutaneous auricular vagus nerve stimulation (taVNS) is a relatively novel noninvasive neurostimulation method that is believed to mimic the effects of invasive cervical VNS. It has recently been ...

Risk of Death in the Elderly with Excessive Daytime Sleepiness, Insomnia and Depression: Prospective Cohort Study in an Urban Population in Northeast Brazil.

Jun 24, 2021

The close relationship between sleep regulation and cardiovascular events is one of the main focuses of research in contemporary medicine. Sleep habits and characteristics interfere with the cardiac r...

Validity and reliability of the Thai version of the pediatric obstructive sleep apnea screening tool.

Jun 24, 2021

Obstructive sleep apnea (OSA) is highly prevalent in children and requires an expensive and relatively unavailable sleep study for diagnosis. This study was undertaken to translate the previously vali...

Study on the mechanism of regulating the hypothalamic cortical hormone releasing hormone/corticotropin releasing hormone type I receptor pathway by vibro-annular abdominal massage under the brain-intestine interaction in the treatment of insomnia.

Jun 10, 2021

Insomnia is a common disease associated with different nervous system stress response and endocrine disorders. It has been reported previously that abdominal vibration and ring massage therapy can sig...

Effects of Lemborexant on the Pharmacokinetics of Oral Contraceptives: Results From a Phase 1 Drug-Drug Interaction Study in Healthy Females.

Jun 10, 2021

Lemborexant is a dual orexin receptor antagonist approved in multiple countries including the United States, Canada, and Japan for the treatment of insomnia in adults. As women of childbearing potenti...

Association between perceived stress and depression among medical students during the outbreak of COVID-19: The mediating role of insomnia.

Jun 10, 2021

The purpose of this study was to explore the association between perceived stress and depression among medical students and the mediating role of insomnia in this relationship during the COVID-19 pand...

Lemborexant for the Treatment of Insomnia: Direct and Indirect Comparisons With Other Hypnotics Using Number Needed to Treat, Number Needed to Harm, and Likelihood to Be Helped or Harmed.

Jun 03, 2021

To describe lemborexant for the treatment of insomnia () in adults using number needed to treat (NNT), number needed to harm (NNH), and likelihood to be helped or harmed (LHH). Lemborexant data were ...

Automatic segmentation of the pharyngeal airway space with convolutional neural network.

Jun 03, 2021

This study proposed and investigated the performance of a deep learning based three-dimensional (3D) convolutional neural network (CNN) model for automatic segmentation of the pharyngeal airway space ...

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