Measuring Primary Care Across 35 OECD Countries.
To examine the psychometric properties and scores of the Person-Centered Primary Care Measure (PCPCM) in 28 languages and 35 Organisation for Economic Co-operation and Development (OECD) cou...
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Class 3 obesity is not associated with same-day admission in obese patients undergoing parathyroidectomy.
Rising rates of obesity and outpatient performance of parathyroidectomies are making it increasingly crucial to investigate the association of obesity with post-operative complications.To de...
Differences in Lifetime Earning Potential Between Pediatric and Adult Physicians.
Compare lifetime earning potential between academic pediatric and adult medicine generalists and subspecialists. Evaluate the effect of decreasing the length of training for pediatric subspe...
Yoga for treating low back pain: a systematic review and meta-analysis.
Yoga is frequently used for back pain relief. However, evidence was judged to be of only low- or moderate. To assess the efficacy and safety of yoga in patients with low back pain a meta-ana...
PRMT7 modulates neuronal excitability by interacting with NaV1.9.
Human NaV1.9 (hNaV1.9), encoded by SCN11A, is preferentially expressed in nociceptors, and its mutations have been linked to pain disorders. NaV1.9 could be a promising drug target for pain ...
Diversity of inhibitory and excitatory parvalbumin interneuron circuits in the dorsal horn.
Parvalbumin-expressing interneurons (PVINs) in the spinal dorsal horn are found primarily in laminae II inner and III. Inhibitory PVINs (iPVINs) play an important role in segregating innocuo...
Long-term outcome after midline lumbar fusion for the treatment of lumbar spine instability due to degenerative disease.
New surgical techniques have been developed to minimize perioperative damage to paravertebral stabilizing musculotendinous system. Among them, midline lumbar fusion (MIDLF) shows to be a via...
Risk of hospitalised falls and hip fractures in working age adults receiving mental health care.
This retrospective cohort study investigates risks of hospitalised fall or hip fractures in working age adults receiving mental health care in South London.Patients aged 18 to 64, who receiv...
Automatic bone maturity grading from EOS radiographs in Adolescent Idiopathic Scoliosis.
Adolescent Idiopathic Scoliosis (AIS) is a deformation of the spine and it is routinely diagnosed using posteroanterior and lateral radiographs. The Risser sign used in skeletal maturity ass...
Bioinspired peptide adhesion on Ti implants alleviates wear particle-induced inflammation and improves interfacial osteogenesis.
In the inflammatory peri-implant microenvironment, excessive polarization of macrophages to the proinflammatory M1 phenotype can trigger the secretion of inflammatory cytokines, which promot...
MRI study of changes in knee bone marrow edema-like signal in asymptomatic amateur marathon runners before and after half-marathon running.
To evaluate the incidence of knee bone marrow edema-like signal and its changes before and after running a half marathon running in asymptomatic amateur marathon runners to explore the impac...
A core-shell nanoplatform as a nonviral vector for targeted delivery of genes to the retina.
Retinal diseases, including age-related macular degeneration (AMD), are a major cause of blindness. Efficient delivery of therapeutic genes to retinal cells to treat retinal disease is a for...
Using electronic health records to develop and validate a machine-learning tool to predict type 2 diabetes outcomes: a study protocol.
Type 2 diabetes mellitus (T2DM) is a major cause of blindness, kidney failure, myocardial infarction, stroke and lower limb amputation. We are still unable, however, to accurately predict or...
A Novel Stimuli-Responsive Injectable Antibacterial Hydrogel to Achieve Synergetic Photothermal/Gene-Targeted Therapy towards Uveal Melanoma.
Uveal melanoma (UM) is the most prevalent primary intraocular malignant tumor with a high lethal rate. Patients who undergo conventional enucleation treatments consistently suffer permanent ...
Prevalence and time trends of refractive error in Chinese children: A systematic review and meta-analysis.
To investigate the prevalence and time trends of refractive error (RE) among Chinese children under 18 years old.PubMed, Embase, Web of Science were searched for articles that estimated prev...
Multiple Evanescent White Dot Syndrome (MEWDS) Associated with Progression of Lacquer Cracks in High Myopia.
To report a case of multiple evanescent white dot syndrome (MEWDS) associated with acute progression of lacquer cracks in high myopia.A 41-year-old female patient with high myopia developed ...
Biomechanics of Ophthalmic Crosslinking.
Crosslinking involves the formation of bonds between polymer chains, such as proteins. In biological tissues, these bonds tend to stiffen the tissue, making it more resistant to mechanical d...
Clinical evaluation of meibomian gland dysfunction in patients with keratoconus.
To investigate the association of keratoconus (KC) with meibomian gland dysfunction (MGD) and to describe the epidemiological characteristics of MGD in this disease.In this observational stu...
The ocular surface findings in alopecia areata patients: clinical parameters and impression cytology.
The objective of this study was to examine the effects of alopecia areata (AA) on the ocular surface and conjunctival cytology.A total of 48 subjects were included in the present study. Twen...
Tear metabolomics highlights new potential biomarkers for differentiating between Sjögren's syndrome and other causes of dry eye.
The lacrimal exocrinopathy of primary Sjögren's syndrome (pSS) is one of the main causes of severe dry eye syndrome and a burden for patients. Early recognition and treatment could prevent ...
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