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OB/GYN General

Predictors of Medication Initiation and Retention in Treatment for Opioid Use Disorder in Pregnant Women in the United States, 2013–2017

Jan 21, 2022

For a study, researchers described trends and characteristics related to opioid use disorder (OUD) medication administration and treatment retention among pregnant women with OUD. A retrospective, cou...

A Wireless Self-Guided Fatal Heart Rate Monitor's Accuracy, Clinical Utility, and Usability

Jan 21, 2022

For a study, researchers tried to assess the accuracy, clinical value, and usability of a wireless fetal and maternal heartbeat monitor for monitoring fetal heart rate (FHR). A convenience sample of w...

Experiences of pregnant women and healthcare professionals of participating in a digital antenatal CMV education intervention.

Jan 17, 2022

The study aimed to explore the perspectives of participating pregnant women and Health Care Professionals (HCPs) towards receiving and providing cytomegalovirus (CMV) education so that barriers and fa...

Factors associated with poor maternal health care services utilization in Eswatini: A secondary analysis of a nationally representative household survey.

Jan 17, 2022

This study investigated the prevalence and factors associated with poor maternal health care services utilization (MHCSU) i.e., having < 4 antenatal care (ANC) visits, not delivering at a health fa...

Advocating for equitable management of hereditary cancer syndromes.

Jan 17, 2022

The potential for preventive medicine to lead to more equitable health outcomes exists with the inclusion of genetic testing in medicine. Because of the medical implications of genetic testing for he...

Identification of novel discoidin domain receptor 1 (DDR1) inhibitors using E-pharmacophore modeling, structure-based virtual screening, molecular dynamics simulation and MM-GBSA approaches.

Jan 17, 2022

Dysregulation of the discoidin domain receptor (DDR1), a collagen-activated receptor tyrosine kinase, has been linked to several human cancer diseases including non-small cell lung carcinoma (NSCLC), ...

The endometriosis daily diary: qualitative research to explore the patient experience of endometriosis and inform the development of a patient-reported outcome (PRO) for endometriosis-related pain.

Jan 17, 2022

Endometriosis is a chronic disorder of the female reproductive system characterized by debilitating symptoms, particularly endometriosis-related pain (ERP). Patient-reported outcome (PRO) measures of ...

An integrated in silico analysis highlighted angiogenesis regulating miRNA-mRNA network in PCOS pathophysiology.

Jan 17, 2022

Polycystic ovary syndrome (PCOS) is a heterogeneous endocrinopathy and a leading cause of anovulatory infertility. Angiogenesis is vital for ovarian folliculogenesis. The expression of angiogenesis-as...

Evolution of low HER2 expression between early and advanced-stage breast cancer.

Jan 17, 2022

Low human epidermal growth factor receptor 2 (HER2) expression is emerging as an actionable biomarker for the treatment of breast cancer (BC) with novel anti-HER2 drugs. However, the evolution of this...

Signaling pathways modulated by miRNAs in breast cancer angiogenesis and new therapeutics.

Jan 17, 2022

MicroRNAs (miRNAs) act as oncogenes or tumor suppressors by suppressing the expression of target genes, some of which are engaged in angiogenic signaling pathways directly or indirectly. Tumor develop...

iSingle Dose Antibiotic Therapy for Urinary Infections during Pregnancy: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.

Jan 10, 2022

During pregnancy, urinary infections are an important cause of maternofetal morbimortality and may lead to several complications.Verify whether the use of antibiotic therapy in a single dose when comp...

The Diagnostic Accuracy Of Procalcitonin for Urinary Tract Infection in Hospitalized Older Adults: a Prospective Study.

Jan 10, 2022

The diagnosis of urinary tract infection (UTI) is challenging among hospitalized older adults, particularly among those with altered mental status.To determine the diagnostic accuracy of procalcitonin...

Maternal Physical Activity at Term and Spontaneous Labor: A Case-Crossover Study.

Jan 10, 2022

This study assessed associations between antenatal physical activity and the onset of spontaneous labor (SL).Data were taken from 541 participants in the third pregnancy, infection, and nutrition stud...

RNA biomarkers from proximal liquid biopsy for diagnosis of ovarian cancer.

Jan 10, 2022

Most ovarian cancer patients are diagnosed at an advanced stage and have a high mortality rate. Current screening strategies fail to improve prognosis because markers that are sensitive for early stag...

Hyperoside Supplementation in Preservation Media Surpasses Vitamin C Protection Against Oxidative Stress-Induced Damages in Human Spermatozoa.

Jan 10, 2022

Oxidative Stress (OS) is reported as one of the main causes of male infertility. Infertile couples often resort to assisted reproductive technology (ART) to achieve parenthood. However, preparation fo...

Insulin resistance and the development of breast cancer in premenopausal women: the Kangbuk Samsung Health Study.

Jan 10, 2022

Research on the role of insulin resistance (IR) in breast cancer risk in premenopausal women is scarce. We aimed to investigate the relationship between IR and the development of breast cancer in prem...

Multidisciplinary Programed Learning Simulation to Improve Visual Blood Loss Estimation for Obstetric Trauma Scenarios.

Jan 10, 2022

We designed and implemented a Programmed Learning Simulation (PLS) exercise depicting obstetric scenarios of hemorrhage to train anesthesiologists, ancillary staff, and surgeons to accurately estimate...

Fertility care expectations: what do PLHIV and health care providers in Jamaica know about assisted reproduction services for safe conception?

Jan 10, 2022

Increased life expectancy among persons living with HIV (PLHIV) has increased the desire for parenthood. It is therefore important that PLHIV and health care providers (HCPs) are aware of the availabl...

Medical vs. Surgical Approach to Septic Arthritis Initial Treatment

Jan 05, 2022

For this study researchers wanted to assess the functional outcomes of two different technique types, medicinal and surgical, employed in the treatment of native joint septic arthritis. They evaluated...

Consensus-Conference Endorsements and Recommendations on the Diagnosis and Treatment of Chikungunya-Related Inflammatory Arthropathies

Jan 04, 2022

Although mortality rates associated with chikungunya (CHIK) outbreaks in Latin America's (LA's) dengue-endemic rural and new urban areas are low, dealing with symptoms and sequelae can both produce a ...