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OB/GYN General

Bacterial profile and antimicrobial susceptibility pattern of urinary tract infection among diabetic patients at Bule Hora University Teaching Hospital, Southern Ethiopia.

Jul 07, 2025

Urinary tract infections (UTIs) are among the most common infectious diseases in both hospital and community settings, leading to increased morbidity and mortality, particularly in patients with DM du...

A qualitative investigation of the factors influencing eating disorder symptomology during the postpartum period.

Jul 07, 2025

The perinatal period can be a challenging time for women with current or historical eating disorder (ED) experience. Maternal EDs are associated with risks to both the mother and the child. During pre...

Axillary Management for Patients Undergoing Total Mastectomy and a Positive Sentinel Lymph Node: Is Axillary Dissection Necessary?

Jul 07, 2025

We sought to evaluate whether patients with breast cancer who undergo a total mastectomy (TM) can safely forgo a completion axillary lymph node dissection (cALND) in the presence of one to three posit...

Optogenetic-Controlled iPSC-Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice.

Jul 07, 2025

Induced pluripotent stem cells (iPSCs) share similar cellular features and various antigens profiles with cancer cells. Leveraging these characteristics, iPSCs hold great promise for developing wide-s...

POLR3A rare variants in a patient with intellectual disability, ataxic gait and cortical malformations: a case-report.

Jun 16, 2025

Recessive mutations in POLR3A exhibit considerable phenotypic diversity, spanning from severe childhood-onset hypomyelinating leukodystrophic syndrome to less severe gait disorders, which may present ...

The hidden causes of pregnancy loss: a closer look.

Jun 16, 2025

Unexpected pregnancy loss can be a traumatic experience for fertile couples. The aim of the study was to assess the nature and type of chromosomal variants involved in early and late pregnancy loss an...

Chloroquine as a potential anticancer agent for triple-negative breast cancer: effects on MDA-MB-231 cells.

Jun 09, 2025

Breast cancer is a major cause of mortality among women worldwide, with triple-negative breast cancer (TNBC) presenting a particularly serious clinical challenge due to its low survival rates and high...

Association between preoperative glycaemic control (HbA1c) and early outcomes following primary hip and knee arthroplasty.

Jun 02, 2025

This study investigates the relationship between diabetes mellitus (DM), glycated haemoglobin (HbA1c), and postoperative outcomes among patients undergoing hip and knee arthroplasty.We conducted a sin...

Ultrasound guided transabdominal botulinum toxin injection for refractory overactive bladder treatment.

May 26, 2025

To evaluate the efficacy and safety of ultrasound - guided transabdominal injection of Botulinum toxin A (BoNT - A) in the treatment of refractory overactive bladder (rOAB). This retrospective cohort ...

A pilot study of apolipoprotein E genotype and associations with maternal lipid levels and small for gestational age outcomes in non-hypertensive pregnancies.

May 26, 2025

The aim of the present pilot study was to determine associations between maternal Apolipoprotein E (ApoE) genotype, lipid levels during pregnancy, fetal growth, and placental pathology.In this case-co...

Causal relationship between citrate and gestational diabetes mellitus: a two-sample Mendelian randomization analysis.

May 26, 2025

Diabetes Mellitus (GDM) is a common metabolic disease during pregnancy, mainly manifested as impaired glucose tolerance in the middle and late stages of pregnancy. As a key intermediate product in the...

MobNas ensembled model for breast cancer prediction.

May 26, 2025

Breast cancer poses a real and immense threat to humankind, thus a need to develop a way of diagnosing this devastating disease early, accurately, and in a simpler manner. Thus, while substantial prog...

Does early surgery within 48 hours improve clinical outcomes in elderly hip fractures? A matched cohort study of 1776 hip fractures.

May 19, 2025

The aim of this study was to determine if a delay to surgery of more than 48 h was associated with poorer functional outcomes and increased 1-year mortality rates for elderly hip fractures.A retrospe...

Labor induction in adolescent pregnancies - A scoping review.

May 19, 2025

This scoping review explores the need for labor induction in adolescent pregnancies (≤19 years). It aims to identify and synthesize evidence on adolescent motherhood's unique challenges and implic...

A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment.

May 19, 2025

Dissecting cellulitis of the scalp (DCS) is a type of neutrophilic scarring alopecia identified by the development of folliculitis with clusters of perifollicular pustules and then progresses to absce...

Clinical application of vein visualization apparatus AccuVein500 in breast cancer surgery: a case report.

May 19, 2025

AccuVein can help visualize superficial veins and is generally used as an auxiliary device to identify patterns of veins that are difficult to locate for collecting blood and securing venous lines. Ev...

Comparison of Enzian and rASRM classifications in predicting symptoms of sexual dysfunction in endometriosis.

May 12, 2025

Endometriosis is known to negatively impact sexual function; however, limited research has explored whether classification systems can help pinpoint specific anatomical locations associated with sexua...

Survival outcomes after pathologic complete response with neoadjuvant endocrine therapy vs. neoadjuvant chemotherapy: a retrospective national database study.

May 12, 2025

Neoadjuvant therapies can result in pathologic complete response (pCR) in patients with breast cancer, which can be predictive of long-term outcomes. Patients with estrogen receptor positive (ER +) ...

Changes of Aortic Elastic Properties in Normal Fetuses During the Second Half of Pregnancy.

May 05, 2025

The purpose of the study was to observe the elastic properties of the aorta in normal fetuses by M-mode echocardiography.This was a prospective cross-sectional study performed in 402 normal fetuses du...

Exosomal miR-122-5p for regulation of secretory functions of fibroblasts and promotion of breast cancer metastasis by targeting MKP-2: an experimental study.

May 05, 2025

Tumor metastasis is a major obstacle for the effective treatment of breast cancer. Some studies showed that exosomes could promote tumor distant metastasis by establishing pre-metastasis niches (PMN)....

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