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STDs

A Kinesin-3 recruitment complex facilitates axonal sorting of enveloped alpha herpesvirus capsids.

Jan 30, 2020

Axonal sorting, the controlled passage of specific cargoes from the cell soma into the axon compartment, is critical for establishing and maintaining the polarity of mature neurons. To delineate axona...

Prevalence of human papillomavirus in the saliva of sexually active women with cervical intraepithelial neoplasias.

Jan 23, 2020

The main objective of this study was to estimate the prevalence of human papillomavirus-DNA (HPV-DNA) in the saliva of sexually active women with HPV-related cervical intraepithelial neoplasias (CIN) ...

Stress keratin 17 enhances papillomavirus infection-induced disease by downregulating T cell recruitment.

Jan 23, 2020

High-risk human papillomaviruses (HPVs) cause 5% of human cancers. Despite the availability of HPV vaccines, there remains a strong urgency to find ways to treat persistent HPV infections, as current ...

Biosynthesis and Half-Life of MBX-2168-triphosphate in Herpes Virus-Infected Cells

Jan 23, 2020

The third generation of methylenecyclopropane nucleoside analogs (MCPNAs) elicit an anti-viral effect against all three sub-classes of herpes viruses without inducing cytotoxicity in vitro. It has bee...

Human Liver Memory CD8 T Cells Use Autophagy for Tissue Residence

Jan 23, 2020

Tissue-resident memory T cells have critical roles in long-term pathogen and tumor immune surveillance in the liver. We investigate the role of autophagy in equipping human memory T cells to acquire...

Antiviral Activity of a Arisaema Tortuosum Leaf Extract and Some of its Constituents against Herpes Simplex Virus Type 2.

Jan 23, 2020

Infections caused by HSV-2 are a public health concern worldwide, and there is still a great demand for the discovery of novel anti-herpes virus agents effective against strains resistant to current a...

Protection Similar With Single, Multiple HPV Vaccine Doses

Dec 28, 2019

Infection with HPV 6, 11, 16, 18 less prevalent among women receiving one, two, three doses of HPV vaccine. FRIDAY, Dec. 27, 2019 (HealthDay News) -- U.S. women who have received one dose of huma...

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