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Brain Cancer Oncology

Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System (LAANTERN): 12-Month Outcomes and Quality of Life After Brain Tumor Ablation.

Apr 22, 2020

Laser Ablation of Abnormal Neurological Tissue using Robotic NeuroBlate System (LAANTERN) is an ongoing multicenter prospective NeuroBlate (Monteris Medical) LITT (laser interstitial thermal therapy) ...

Residential proximity to power lines and risk of brain tumor in the general population.

Apr 14, 2020

The effect of ELF-MF on human health is still controversial, particularly as regards long-term health effects like cancer. The literature does suggest, however, that they could be involved in the occu...

Machine learning distinguishes neurosurgical skill levels in a virtual reality tumor resection task.

Apr 14, 2020

This study outlines the first investigation of application of machine learning to distinguish "skilled" and "novice" psychomotor performance during a virtual reality (VR) brain tumor resection task. T...

Three-Plane-assembled Deep Learning Segmentation of Gliomas.

Apr 14, 2020

To design a computational method for automatic brain glioma segmentation of multimodal MRI scans with high efficiency and accuracy.The 2018 Multimodal Brain Tumor Segmentation Challenge (BraTS) datase...

Validation study of the Japanese version of MD Anderson Symptom Inventory for Brain Tumor module.

Apr 14, 2020

The MD Anderson Symptom Inventory for Brain Tumor (MDASI-BT) module is a widely used instrument for measuring symptom burden and interference of daily activities in brain tumor patients. This study ai...

A Comparison of Functional Outcomes between Patients admitted to Inpatient Rehabilitation after Initial Diagnosis versus Recurrence of Glioblastoma Multiforme.

Apr 14, 2020

Prior studies of inpatient rehabilitation of brain tumor patients demonstrate similar functional gains as compared to other rehabilitation populations. There are few studies specifically examining the...

Therapy of Sporadic and NF2-Related Vestibular Schwannoma.

Apr 07, 2020

Vestibular schwannoma (VS) is a benign primary brain tumor that occurs sporadic or as part of a genetic syndrome. The most common cause is the mutation of the NF2 tumor suppressor gene that is involve...

The Emerging Roles of RNA Modifications in Glioblastoma.

Apr 07, 2020

Glioblastoma (GBM) is a grade IV glioma that is the most malignant brain tumor type. Currently, there are no effective and sufficient therapeutic strategies for its treatment because its pathological ...

KLF4-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment.

Apr 07, 2020

Meningioma represents the most common primary brain tumor in adults. Recently several non-NF2 mutations in meningioma have been identified and correlated with certain pathological subtypes, locations ...

Ribosomal Protein S6 promotes stem-like characters in glioma cells.

Apr 07, 2020

Glioblastoma multiform (GBM), a lethal brain tumor developing in the white matter of the adult brain, contains a small population of GBM stem cells (GSCs), which potentially cause chemotherapeutic res...

Repolarization of glioblastoma macrophage cells using non-agonistic Dectin-1 ligand encapsulating TLR-9 agonist: plausible role in regenerative medicine against brain tumor.

Apr 07, 2020

Glioblastoma multiforme (GBM) is the most severe forms of brain cancer, eventually becoming the leading cause of brain cancer-related death worldwide. Owing to the bleak surgical interventions and res...

Article Addresses Management of Cancer Care During COVID-19

Mar 29, 2020

MONDAY, March 23, 2020 (HealthDay News) -- Management of cancer care during the coronavirus 2019 (COVID-19) pandemic is addressed in a special feature article published online March 20 in the Journal ...

ATRX/EZH2 complex epigenetically regulates FADD/PARP1 axis, contributing to TMZ resistance in glioma.

Mar 23, 2020

: Glioma is the most common primary malignant brain tumor in adults. Chemoresistance of temozolomide (TMZ), the first-line chemotherapeutic agent, is a major issue in the management of patients with g...

Pre-pregnancy obesity and childhood malignancies: A population-based cohort study.

Mar 23, 2020

Exploring the effect of maternal obesity during pregnancy on the long-term health of offspring is of great importance. The aim of this study was to evaluate the association between maternal pre-pregna...

Cancer Stem Cell Chemotherapeutics Assay for Prospective Treatment of Recurrent Glioblastoma and Progressive Anaplastic Glioma: A Single-Institution Case Series.

Mar 23, 2020

Chemotherapy-resistant cancer stem cells (CSC) may lead to tumor recurrence in glioblastoma (GBM). The poor prognosis of this disease emphasizes the critical need for developing a treatment stratifica...

Development and validation of prediction scores for nosocomial infections, reoperations, and adverse events in the daily clinical setting of neurosurgical patients with cerebral and spinal tumors.

Mar 23, 2020

Various quality indicators are currently under investigation, aiming at measuring the quality of care in neurosurgery; however, the discipline currently lacks practical scoring systems for accurately ...

Exposure to Medical Radiation during Fetal Life, Childhood and Adolescence and Risk of Brain Tumor in Young Age: Results from The MOBI-Kids Case-Control Study.

Mar 23, 2020

We explored the association between ionizing radiation (IR) from pre-natal and post-natal radio-diagnostic procedures and brain cancer risk within the MOBI-kids study.MOBI-kids is an international (Au...

The Bradykinin-BDKRB1 Axis Regulates Gene Expression and Consequential Migration and Invasion of Malignant Glioblastoma Cells via a Ca-MEK1-ERK1/2-NF-κB Mechanism.

Mar 19, 2020

Glioblastoma multiforme (GBM) is the most common form of brain tumor and is very aggressive. Rapid migration and invasion of glioblastoma cells are two typical features driving malignance of GBM. Brad...

Ependymoma Pediatric Brain Tumor Protein Fingerprinting by Integrated Mass Spectrometry Platforms: A Pilot Investigation.

Mar 19, 2020

Ependymoma pediatric brain tumor occurs at approximate frequencies of 10-15% in supratentorial and 20-30% in posterior fossa regions. These tumors have an almost selective response to surgery and rela...

Proton beam therapy utilization in adults with primary brain tumors in the United States.

Mar 19, 2020

The utilization of proton beam therapy (PBT) as the primary treatment of adults with primary brain tumors (APBT) was evaluated through query of the National Cancer Database (NCDB) between the years 20...