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Skin Cancer

LncRNA HOTAIR promotes the invasion and metastasis of oral squamous cell carcinoma through metastasis-associated gene 2.

Jan 30, 2020

Despite therapeutic advancements, there has been little improvement in the survival status of patients with oral squamous cell carcinoma (OSCC). HOX antisense intergenic RNA (HOTAIR) has been shown to...

Assessing potential mechanisms of arsenic-induced skin lesions and cancers: Human and in vitro evidence.

Jan 30, 2020

Environmental exposure to arsenic is a major public health challenge worldwide. In detailing the hallmark signs of chronic arsenic exposure, previous studies have shown that epigenetic and immune dysf...

Artificial Neural Networks allow Response Prediction in Squamous Cell Carcinoma of the Scalp Treated with Radiotherapy.

Jan 23, 2020

Epithelial neoplasms of the scalp account for approximately 2% of all skin cancers and for about 10-20% of the tumors affecting the head and neck area. Radiotherapy is suggested for localized cutaneou...

Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy.

Jan 23, 2020

Due to limited current therapies, metastases are the primary cause of mortality in cancer patients. Here, we employ a fusion compound of the cytokine LIGHT and a vascular targeting peptide (LIGHT-VTP)...

Chromosome 3q26 Gain Is an Early Event Driving Coordinated Overexpression of the PRKCI, SOX2, and ECT2 Oncogenes in Lung Squamous Cell Carcinoma.

Jan 23, 2020

Lung squamous cell carcinoma (LSCC) is a prevalent form of lung cancer exhibiting distinctive histological and genetic characteristics. Chromosome 3q26 copy number gain (CNG) is a genetic hallmark of ...

Interdisciplinary Management of Tumours of the Eyelid

Jan 23, 2020

Skin malignancies are typically localised in areas of the head that are exposed to the sun. Basal cell carcinomas (BCC) are the most frequent malignancies on the facial skin. Their incidence is raisin...

ELF1-mediated LUCAT1 promotes choroidal melanoma by modulating RBX1 expression.

Jan 23, 2020

Long noncoding RNAs (lncRNAs) are essential regulators of gene expression and biological behaviors. However, the contribution of lncRNA LUCAT1 to choroidal melanoma (CM) remains unexplored. Here, we e...

Tivozanib Bests Sorafenib in Metastatic Renal Cell Carcinoma

Dec 23, 2019

Progression-free survival longer in those receiving tivozanib as third- or fourth-line therapy MONDAY, Dec. 23, 2019 (HealthDay News) -- Among patients with metastatic renal cell carcinoma, progres...

2012 to 2014 Saw 41,185 U.S. Patients With Skin Malignancy

Dec 09, 2019

MONDAY, Dec. 9, 2019 (HealthDay News) -- From 2012 to 2014, 41,185 patients with a diagnosis of skin malignancy of the head and neck region were identified, mostly with a diagnosis of nonmelanoma skin...