False-positive mammography results may deter women from continued screening
1. In this cohort study, women were less likely to return for mammogram screening if their...
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Oncology
Belzutifan versus Everolimus for Advanced Renal-Cell Carcinoma
1. Median PFS (5.6 months vs 5.6 months) and median OS (21.4 months vs 18.1 months) were similar...
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Impact of different visceral metastatic sites on survival in metastatic prostate cancer patients
1. In a retrospective analysis of 59,875 patients with metastatic prostate cancer, varying...
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Patient Education Needed to Successfully Integrate PROs Into EHRs
Patients found high value in integrating patient-reported outcomes into electronic health records, but expressed several areas of confusion.
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EHR Nudge Can Reduce Unnecessary Sentinel Lymph Node Biopsy
An EHR nudge intervention targeting surgeons can reduce sentinel lymph node biopsy (SLNB) among women who meet the Choosing Wisely criteria for SLNB omission.
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Esophageal Cancer Disparities Declined From 1999 to 2020
From 1999 to 2020, age-adjusted esophageal cancer mortality decreased among Black adults but stabilized among White adults.
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Substantial Disparities Seen for Men in Cancer Cases & Deaths
Disparities seen in cancer incidence and mortality among men across age groups and countries/territories for 2022 are projected to widen further by 2050.
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Rare Cancers Associated With Poor Psychological Outcomes
Researchers found an increased risk ratio for depression and anxiety among patients with rare cancers, as well as higher incidences of suicide and PTSD.
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Medication-related osteonecrosis of the jaw is prevalent in patients with breast cancer
1. The cumulative incidence of medication-related osteonecrosis of the jaw (MRONJ) in patients...
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Machine learning algorithm demonstrates ability to appropriately identify cancer patients for serious illness conversations
1. Patel and colleagues conducted a secondary economic analysis of a trial that assigned high-risk...
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Brentuximab-based chemotherapy improves survival and reduces toxicity in patients with advanced Hodgkin lymphoma
1. BrECADD resulted in significantly lower treatment-related morbidity than eBEACOPP. 2....
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Metastasis-Directed Therapy to Systemic Therapy for Oligometastatic Pancreatic Ductal Adenocarcinoma
1. The median progression-free survival in the metastasis-directed therapy arm was 10.3 months vs...
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Alternative lung cancer screening criteria may increase sensitivity versus current guidelines
1. In this modeling study, an alternative set of lung cancer screening criteria was more sensitive...
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Cancer screening costs in the United States may exceed $40 billion annually
1. In the United States, the estimated annual cost of cancer screening was $43 billion, with...
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Corticosteroids for Immune-Related Adverse Events and Checkpoint Inhibitor Efficacy
1. When comparing corticosteroid peak dose for immunosuppression for anti–PD-1 plus...
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Novel CAR-T Cell Therapy Shows Promise for Pediatric Diffuse Midline Glioma Treatment
1. Approximately 88% of patients with GD2-positive diffuse midline glioma or other progressive CNS...
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Dose-dense adjuvant therapy with epirubicin and cyclophosphamide effective for breast cancer
1. Dose-dense adjuvant chemotherapy involving sequential epirubicin/cyclophosphamide and docetaxel...
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#VisualAbstract Bilateral Masectomy Reduces Risk of Contralateral Breast Cancer But Does Not Reduce the Breast Cancer Mortality Rate
Click here to read this study in the NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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#VisualAbstract: Blinatumomab Improves Survival in MRD-Negative Acute Lymphoblastic Leukemia in Adults
Click here to read this study in NEJM. ©2024 2 Minute Medicine, Inc. All rights reserved. No...
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TKI With or Without SRS for Brain Metastases From EGFR/ALK Mutated NSCLC
1. Median overall survival was 41 months in the TKI-only group vs 40 months in the TKI-SRS group,...
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