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Ophthalmology General

Eye health literacy across the world and in Australia.

May 05, 2025

Eye health literacy is an important factor in determining eye health outcomes. Ophthalmic disorders are increasingly common due to various factors associated with ageing population and other important...

Understandability and actionability of patient education materials for diabetic retinopathy among indigenous and general populations.

Apr 28, 2025

Effective diabetic retinopathy (DR) patient education materials (PEMs) are vital for improving patient outcomes by fostering understanding and self-management.DR is a leading cause of vision impairmen...

Measurement of static and dynamic pupillary characteristics after implantable collamer lens by sirius anterior segment analysis system.

Apr 14, 2025

This study investigated static and dynamic pupillometry changes before and after ICL V4c implantation under varying light conditions. A prospective study of 210 high myopia patients undergoing V4c ICL...

Comparative performance analysis of global and chinese-domain large language models for myopia.

Apr 14, 2025

The performance of global large language models (LLMs), trained largely on Western data, for disease in other settings and languages is unknown. Taking myopia as an illustration, we evaluated the glob...

3-year results of 0.01% and 0.1% loading dose atropine treatment including washout in Danish children with myopia: a placebo-controlled, randomised clinical trial.

Mar 24, 2025

To examine the safety and efficacy of low-dose atropine (0.01% and 0.1% loading dose) after 2-year treatment and 1-year washout in 6-year-old to 12-year-old Danish children with myopia.Investigator-in...

Simultaneous inhibition of fibroblast growth factor-2 and vascular endothelial growth factor-a with RC28-E in diabetic macular edema: a phase 2 randomised trial.

Mar 24, 2025

To compare different doses and dosing regimens of RC28-E, a novel bispecific antibody that simultaneously binds vascular endothelial growth factor-A (VEGF-A) and fibroblast growth factor-2 (FGF-2), wi...

Vision Restoration through transorbital electrical stimulation in Optic Neuropathy in patients with significant optic atrophy due to primary open-angle glaucoma-a randomised, controlled, double-blind, multicentre clinical trial: the VIRON study protocol.

Feb 17, 2025

Glaucoma is one of the most common causes of blindness and affects more than 70 million people worldwide. The disease is characterised by the loss of retinal ganglion cells associated with a progres...

Predicting visual field global and local parameters from OCT measurements using explainable machine learning.

Feb 17, 2025

Glaucoma is characterised by progressive vision loss due to retinal ganglion cell deterioration, leading to gradual visual field (VF) impairment. The standard VF test may be impractical in some cases,...

Detecting Glaucoma in Highly Myopic Eyes From Fundus Photographs Using Deep Convolutional Neural Networks.

Feb 10, 2025

High myopia (HM) is a major risk factor for glaucoma. However, glaucomatous optic neuropathy is often undiagnosed owing to atypical structural alterations with axial elongation. Moreover, an algorithm...

Real-world study of phakic refractive lens for correction of high myopia.

Feb 03, 2025

To assess the safety and efficacy of phakic refractive lens (PRL) implantation for correcting high myopia, as well as an ophthalmic viscosurgical device-free (OVD-free) method for PRL implantation.In ...

Electroacupuncture alleviates damage to myopic RGCs probably through lncRNA-XR_002789763.1-mediated mitophagy.

Feb 03, 2025

Mitophagy is closely related to the regulation of retinal ganglion cell (RGC) structure and function. Our previous study suggested that long noncoding RNAs (lncRNAs) can cause damage to myopic RGCs. H...

Open challenges for the automatic synthesis of clinical trials.

Feb 03, 2025

An important criterion for selecting clinical trials to be compared in systematic reviews and meta-analyses is that they measure the same outcomes. However, this represents a challenge as there is a w...

Evaluation of dry eye parameters and meibomian gland function using the Lipiscan system in male androgenetic alopecia patients.

Jan 27, 2025

The prevalence of male androgenetic alopecia is increasing worldwide. Evaluation of dry eye parameters and meibomian glands of male androgenetic alopecia patients may help to better understand the eff...

Quarter of a century of contact lens prescribing trends in Australia (2000-2024).

Jan 13, 2025

Knowledge of contact lens prescribing trends can (a) assist practitioners to benchmark their own prescribing habits, (b) help the contact lens industry understand preferred products, and (c) support a...

Changes in corneal wavefront aberrations and anterior segment parameters after horizontal rectus muscle surgeries assessed using Pentacam®.

Jan 13, 2025

Horizontal rectus muscle surgeries may cause changes in corneal and anterior segment parameters. Corneal topography is an important device for identifying these alterations.The aim of this work is to ...

Effectiveness and safety of VISULAS® green selective laser trabeculoplasty: 12 months retrospective data.

Dec 16, 2024

To report the safety and effectiveness of selective laser trabeculoplasty (SLT) using the SLT mode of the VISULAS green laser in patients with primary open-angle glaucoma (POAG). Twelve months results...

Microcirculatory parameters as risk factors for predicting progression of posterior staphyloma in highly myopic eyes: a case-control study.

Dec 02, 2024

To assess the rate of macular blood flow decreasing in adults with and without posterior staphyloma (PS) using optical coherence tomography angiography (OCTA) and to identify risk factors associated w...

Eye diseases in chronic kidney disease: A nationwide longitudinal case-control study in Sweden.

Nov 18, 2024

Chronic kidney disease (CKD) is a growing health issue that is becoming more prevalent globally, increasing financial cost on healthcare systems. The purpose of this study is to investigate the incide...

Genome-wide meta-analysis identifies 22 loci for normal tension glaucoma with significant overlap with high tension glaucoma.

Nov 18, 2024

Primary open-angle glaucoma typically presents as two subtypes. This study aimed to elucidate the shared and distinct genetic architectures of normal-tension (NTG) and high-tension glaucoma (HTG), mot...

Determination of osteopontin in monitoring retinal damage in metabolic syndrome.

Oct 14, 2024

Metabolic syndrome (MetS) is becoming an increasing public health challenge. Many of the individual components of MetS are associated with ocular changes, but it is not yet clear what the association ...

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