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Ophthalmology General

Self-lubricating, Living Contact Lenses.

Apr 08, 2024

The increasing prevalence of dry eye syndrome in aging and digital societies compromises long-term contact lens wear and forces users to regular eye drop instillation to alleviate discomfort. Here we ...

[Preliminary study on automatic quantification and grading of leopard spots fundus based on deep learning technology].

Mar 11, 2024

To achieve automatic segmentation, quantification, and grading of different regions of leopard spots fundus (FT) using deep learning technology. The analysis includes exploring the correlation betwee...

miR-143 promotes cell proliferation, invasion and migration via directly binding to BRD2 in lens epithelial cells.

Mar 11, 2024

Cataract causes the greatest number of blindnesses worldwide. This study aims to investigate the role of miR-143 in lens epithelial cells.Clustering analysis was conducted to systematically compare mi...

Diagnosis of Dry Eye Syndrome Using Ocular Surface Disease Index, Tear Film Break-up Time, and Schirmer Test.

Mar 11, 2024

To evaluate the subjects of possible ocular surface dysfunction in dry eye syndrome (DES) by using Ocular Surface Disease Index (OSDI) questionnaire and correlating it with the tear film break-up time...

Vascular changes of the choroid and their correlations with visual acuity in diabetic retinopathy.

Mar 11, 2024

To investigate changes in the choroidal vasculature and their correlations with visual acuity in diabetic retinopathy (DR).The cohort was composed of 225 eyes from 225 subjects, including 60 eyes from...

Outcomes of Eyes Lost to Follow-up After Treatment With Intraocular or Periocular Steroid Injections.

Mar 11, 2024

To evaluate the visual, intraocular pressure (IOP), and anatomic outcomes of eyes with loss to follow-up (LTFU) after intravitreal or periocular steroid injections. Patients receiving intraocular or...

Eye Pain During Hemodialysis in Severe Proliferative Diabetic Retinopathy With Neovascular Glaucoma.

Mar 11, 2024

To report a case of severe eye pain developing during dialysis. A case report was performed. A 41-year-old man with uncontrolled type 2 diabetes and end-stage nephropathy developed severe pain in t...

The Royal College of Ophthalmologists' National ophthalmology database study of cataract surgery: Report 14, cohort analysis - the impact of CapsuleGuard® utilisation on cataract surgery posterior capsule rupture rates.

Mar 11, 2024

The aim of this study was to investigate whether the use of the silicone tipped irrigation/aspiration (I/A) handpiece CapsuleGuard® (Bausch + Lomb, Laval, Canada) reduced rates of posterior capsule r...

Retinochoroiditis secondary to Rickettsia typhi infection: a case report.

Mar 11, 2024

To report a case of unusual presentation of retinochoroiditis caused by Rickettsia typhi in a patient without prior uveitis.In this case, we describe a 24-year-old male soldier with no previous eye di...

UV light-mediated corneal crosslinking as (lymph)angioregressive pretreatment to promote graft survival after subsequent high-risk corneal transplantation (CrossCornealVision): protocol for a multicenter, randomized controlled trial.

Mar 07, 2024

Good vision highly depends on the transparency of the cornea, which is the "windscreen" of the eye. In fact, corneal blindness due to transparency loss is the second most common cause of blindness wor...

National prevalence of vision impairment and blindness and associated risk factors in adults aged 40 years and older with known or undiagnosed diabetes: results from the SMART-India cross-sectional study.

Mar 04, 2024

National estimates of the prevalence of vision impairment and blindness in people with diabetes are required to inform resource allocation. People with diabetes are more susceptible to conditions such...

Ocular surface and meibomian gland evaluation in euthyroid Graves' ophthalmopathy.

Mar 04, 2024

Euthyroid Graves' ophthalmology (EGO) refers to the subgroup of thyroid eye disease patients with distinct clinical presentations. This study evaluated the ocular surface and meibomian gland changes i...

Saikosaponin F ameliorates depression-associated dry eye disease by inhibiting TRIM8-induced TAK1 ubiquitination.

Mar 04, 2024

Saikosaponin F (SsF) is one of the major active ingredients of Radix Bupleuri, an herb widely used in the treatment of depression. Studies have shown that dry eye disease often occurs together with de...

Glucose tolerance and insulin resistance/sensitivity associate with retinal layer characteristics: the LIFE-Adult-Study.

Mar 04, 2024

As the prevalence of insulin resistance and glucose intolerance is increasing throughout the world, diabetes-induced eye diseases are a global health burden. We aim to identify distinct optical bands ...

Determinants of non-diabetic kidney diseases in type 2 diabetic patients: Twenty years of single center experience.

Mar 04, 2024

Diabetic nephropathy is one of the most common complications associated with diabetes. However, non-diabetic kidney disease has been reported in patients with type 2 diabetes at varying incidence rate...

Evaluating the accuracy of the Ophthalmologist Robot for multiple blindness-causing eye diseases: a multicentre, prospective study protocol.

Mar 04, 2024

Early eye screening and treatment can reduce the incidence of blindness by detecting and addressing eye diseases at an early stage. The Ophthalmologist Robot is an automated device that can simultaneo...

Circadian rhythm of intraocular pressure.

Mar 04, 2024

Intraocular pressure (IOP) plays a crucial role in glaucoma development, involving the dynamics of aqueous humor (AH). AH flows in from the ciliary body and exits through the trabecular meshwork (TM)....

Accuracy of an Artificial Intelligence Chatbot's Interpretation of Clinical Ophthalmic Images.

Mar 04, 2024

Ophthalmology is reliant on effective interpretation of multimodal imaging to ensure diagnostic accuracy. The new ability of ChatGPT-4 (OpenAI) to interpret ophthalmic images has not yet been explored...

How Can Artificial Intelligence Be Implemented Effectively in Diabetic Retinopathy Screening in Japan?

Feb 26, 2024

Diabetic retinopathy (DR) is a major microvascular complication of diabetes, affecting a substantial portion of diabetic patients worldwide. Timely intervention is pivotal in mitigating the risk of bl...

Ultra-Wide-Field Optical Coherence Tomography and Gaussian Curvature to Assess Macular and Paravascular Retinoschisis in High Myopia.

Feb 26, 2024

To evaluate the severity and related factors of macular retinoschisis (MRS) and paravascular retinoschisis (PVRS) in high myopia (HM) using ultra-wide-field optical coherence tomography (UWF-OCT) and ...

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