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Ophthalmology General

[Effect of acupuncture on expression of transfer growth factor-β1 in lacrimal gland of rabbits with dry eye].

Sep 24, 2020

To observe the effect of acupuncture on expression of transforming growth factor-β1(TGF-β1) in lacrimal gland of rabbits with dry eye, so as to explore its underlying mechanism in improving dry eye....

Punctate fluorescein staining scores in dogs with or without aqueous tear deficiency.

Sep 24, 2020

To compare the superficial punctate fluorescein staining in dogs with and without aqueous tear deficiency.An eye from each client-owned dogs presented to Triangle Animal Eye Clinic between January and...

Evaluation of microvascular changes in retinal zones and optic disc in pediatric patients with type 1 diabetes mellitus.

Sep 24, 2020

The objective of this study was to evaluate the vascular parameters of the retinal zones and the optic disc (OD) with the use of optical coherence tomography angiography (OCTA) in pediatric patients w...

The association between carotid disease, arterial stiffness and diabetic retinopathy in type 2 diabetes: the Fremantle Diabetes Study Phase II.

Sep 24, 2020

To determine whether macrovascular disease assessed by carotid ultrasonography and arterial stiffness by pulse wave velocity are independently associated with diabetic retinopathy in type 2 diabetes.A...

Ab interno trabeculotomy combined with cataract extraction in eyes with primary open-angle glaucoma.

Sep 24, 2020

To investigate the efficacy and safety of ab interno trabeculotomy using the VISCO360® Viscosurgical System (Sight Sciences, Inc., Menlo Park, CA, USA) combined with cataract extraction in the treatm...

l-3,4-Dihydroxyphenylalanine templated anisotropic gold nano/micro-roses as potential disrupters/inhibitors of α-crystallin protein and its gleaned model peptide aggregates.

Sep 24, 2020

Cataract, the major cause of blindness worldwide occurs due to the misfolding and aggregation of the protein crystallin, which constitute a major portion of the lens protein. Other than the whole prot...

Effect of diabetes control on rates of structural and functional loss in patients with glaucoma.

Sep 24, 2020

To investigate the association between levels of diabetes mellitus (DM) control and rates of visual field and retinal nerve fiber layer (RNFL) loss over time in glaucoma.Retrospective cohort study.351...

Retinoprotective effect of donepezil in diabetic mice involves mitigation of excitotoxicity and activation of PI3K/mTOR/BCl pathway.

Sep 24, 2020

Donepezil (DNPZ) has shown neuroprotective effect in many disorders. The current study tested the putative retinoprotection provided by donepezil in mouse diabetic retinopathy. Swiss albino mice were ...

Efficacy and Safety of Phospholipid Nanoemulsion-Based Ocular Lubricant for the Management of Various Subtypes of Dry Eye Disease: A Phase IV, Multicenter Trial.

Sep 21, 2020

To evaluate the clinical efficacy and safety of propylene glycol/hydroxypropyl-guar (PG-HPG)-based nanoemulsion (Systane Complete) lubricant eye drops in participants with dry eye disease (DED).In thi...

Resveratrol Rescues Human Corneal Epithelial Cells Cultured in Hyperosmolar Conditions: Potential for Dry Eye Disease Treatment.

Sep 21, 2020

Dry eye disease (DED) is a common ocular surface condition across age groups. Recently, vitamin D deficiency has gained importance as a causative factor, and its supplementation alleviates symptoms of...

New application for assessment of dry eye syndrome induced by particulate matter exposure.

Sep 21, 2020

Dry eye syndrome (DES) is a multifactorial condition characterized by insufficient tear lubrication and eye irritation. Air pollutants, including particulate matter (PM), are an emerging threat to hum...

Intravitreal Aflibercept Treatment Strategies in Routine Clinical Practice of Neovascular Age-Related Macular Degeneration in Belgium: A Retrospective Observational Study.

Sep 21, 2020

STELLAR was a Belgian, multicentre, retrospective, observational chart review that described the utilization (number of injections and treatment regimen) and effectiveness of intravitreal aflibercept ...

Fluorescent aptasensor based on G-quadruplex-assisted structural transformation for the detection of biomarker lipocalin 1.

Sep 21, 2020

Diabetic retinopathy (DR) is the leading global cause of blindness in the working-age population. Early diagnosis and intervention can effectively reduce the risk for blindness. However, the current d...

XEN45 Gel Stent implantation in eyes with primary open angle glaucoma: A study from a single hospital in Taiwan.

Sep 21, 2020

To evaluate the effectiveness and safety of the XEN45 Gel Stent in East Asian patients with primary open angle glaucoma (POAG).We retrospectively reviewed thirty-seven medically uncontrolled POAG pati...

Inclusion of diabetic retinopathy screening strategies in national-level diabetes care planning in low-income and middle-income settings: protocol for a scoping review.

Sep 21, 2020

The diabetes mellitus (DM) epidemic is a major public health concern globally, with the highest-burden in low-income and middle-income countries (LMICs). Diabetic retinopathy (DR) is a microvascular c...

Sphingolipids as Critical Players in Retinal Physiology and Pathology.

Sep 21, 2020

Sphingolipids have emerged as bioactive lipids involved in the regulation of many physiological and pathological processes. In the retina, they have been established to participate in numerous process...

Management of congenital nasolacrimal duct obstruction: results of a national survey of paediatric and oculoplastic ophthalmologists.

Sep 21, 2020

To survey variation in management of congenital nasolacrimal duct obstruction (CNLDO) by oculoplastic and paediatric ophthalmologists in the UK.A 14-question online survey was sent to all members of t...

Association of Adrenal Insufficiency With Pediatric Pseudotumor Cerebri Syndrome.

Sep 21, 2020

Pediatric pseudotumor cerebri syndrome pathophysiology is complex and not well delineated. Therefore, it is important to identify potential contributors or targets underlying the primary pathogenesis ...

Six-year Incidence and Risk Factors of Primary Glaucoma in the Singapore Indian Eye Study.

Sep 21, 2020

To determine the 6-year incidence of primary glaucoma and its risk factors in an Indian population in Singapore DESIGN: Cohort population-based study PARTICIPANTS: Indian adults aged between 40 and 80...

Managing Patient Expectations in Dry Eye Disease

Sep 18, 2020

When managing dry eye disease (DED), ensuring realistic patient expectations is critical to optimizing adherence to treatment and improving patient satisfaction. Clinicians are urged to educate patien...

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