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Ophthalmology General

Clinical Factors Affecting Operating Room Utilization in Cataract Surgery

Feb 13, 2020

To identify preoperative clinical characteristics affecting cataract surgery operative time.Academic center.Large-scale retrospective cohort study.All cases of cataract extraction by phacoemulsificati...

Corneal biomechanical responses detected using corvis st in primary open angle glaucoma and normal tension glaucoma.

Feb 13, 2020

Structural differences have been reported between primary open angle glaucoma (POAG) and normal tension glaucoma (NTG), and biomechanical differences between POAG and NTG may account for why NTG patie...

Visual function evaluation for low vision patients with advanced glaucoma.

Feb 13, 2020

This study aimed to compare various visual function parameters for evaluating the quality of life (QOL) of patients with advanced glaucoma with low vision.In total, 44 eyes of advanced glaucoma patien...

A real-life prospective study on the efficacy of the XEN 45 stent: a European study.

Feb 13, 2020

This study investigated the efficacy and safety of a cross-linked collagen stent (XEN 45) with or without cataract surgery in the treatment of glaucoma.Real-life setting.Prospective, open-label, multi...

Complications of cosmetic iris implants: French series of 87 eyes.

Feb 13, 2020

Iris intraocular implants were developed to manage congenital or traumatic iris defects. However, they are also used to change the color of patient eyes. The aim of this retrospective series was to re...

Cataract, glaucoma, possible Marfan syndrome, and conception aspirations.

Feb 13, 2020

A 36-year-old highly myopic woman was referred for management of both cataract and glaucoma. Her ocular history included retinal detachment repair in each eye, 9 years earlier in the right eye and 7 y...

A low cost surrogate eye model for corneal foreign body removal.

Feb 13, 2020

Patients commonly present to the Emergency Department with a corneal foreign body (FB). There is currently a lack of adequate training for junior doctors in the management of this condition. Our self-...

Mortality and Neurodevelopmental Outcomes in the Heart Rate Characteristics Monitoring Randomized Controlled Trial.

Feb 10, 2020

To test whether the composite outcome of death or neurodevelopmental impairment (NDI) at 18-22 months corrected age for infants ≤1000 g at birth is decreased by continuous monitoring of heart rate...

Increased circulating levels of Factor H-Related Protein 4 are strongly associated with age-related macular degeneration.

Feb 10, 2020

Age-related macular degeneration (AMD) is a leading cause of blindness. Genetic variants at the chromosome 1q31.3 encompassing the complement factor H (CFH, FH) and CFH related genes (CFHR1-5) are maj...

Vitamin A: its many roles-from vision and synaptic plasticity to infant mortality.

Feb 10, 2020

The recognition that a dietary factor is essential to maintain good and sensitive vision as well as overall health goes back over 3,000 years to the ancient Egyptians. With the discovery of the vitam...

Managing Dry Eye Disease and Facilitating Realistic Patient Expectations

Feb 10, 2020

Dry eye disease (DED) is a multifactorial disease of the ocular surface characterized by loss of homeostasis of the tear film and accompanied by ocular signs and symptoms such as corneal and conjuncti...

An Updated Systematic Review With Meta-Analysis Of Randomized Trials On Topical Cyclosporin A For Dry-Eye Disease.

Feb 10, 2020

To evaluate the effects of topical cyclosporin A (CsA) and artificial tears (ATs) for treating patients with dry-eye disease (DED).On January 25, 2019, five electronic databases and reference lists we...

Aqueous deficiency is a contributor to evaporation-related dry eye disease.

Feb 10, 2020

Dry eye disease aetiologies can be classified dichotomously into aqueous deficient and evaporative types although many cases involve combinations of both. Differential diagnosis can be confounded by s...

Scleral lens for severe dry eye status post lacrimal gland resection for adenoid cystic carcinoma.

Feb 10, 2020

Scleral contact lenses (SCLs) are devices that allow a fluid reservoir between the contact lens and the cornea, providing both improved lubrication and refraction. Consequently, SCLs have been used fo...

Associations between the menstrual cycle, lifestyle factors and clinical assessment of the ocular surface: a prospective observational study.

Feb 10, 2020

Little is known about the ocular surface changes over the menstrual cycle in young women and the interactions with lifestyle factors. Therefore, the purpose of this study was to explore the associatio...

Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy.

Feb 10, 2020

Alpha-1-antitrypsin is a protein involved in avoidance of different processes that are seen in diabetic retinopathy pathogenesis. These processes include apoptosis, extracellular matrix remodeling and...

Diabetic Retinopathy Screening Using a Gold Nanoparticle-Based Paper Strip Assay for the At-Home Detection of the Urinary Biomarker 8-Hydroxy-2'-deoxyguanosine (8-OHdG).

Feb 10, 2020

To assess a smartphone-based, gold nanoparticle (AuNP)-based colorimetric lateral flow immunoassay paper sensor for quantifying urine 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a biomarker for diabetic r...

The effect of glycaemia on choroidal thickness in different stages of diabetic retinopathy.

Feb 10, 2020

The purpose of this study was to evaluate the influence of renal and glycemic parameters on choroidal thickness (CT) in patients with diabetes with and without diabetic retinopathy (DR).This cross-sec...

An Economic Evaluation of Voretigene Neparvovec for the Treatment of Biallelic RPE65-Mediated Inherited Retinal Dystrophies in the UK.

Feb 10, 2020

Voretigene neparvovec (VN) is a gene therapy and the first approved pharmacological treatment for biallelic RPE65-mediated inherited retinal dystrophies (IRD), a rare condition that starts in early li...

Benzodiazepine Use and Risk of Acute Angle-Closure Glaucoma: A Population-Based Case-Crossover Study.

Feb 10, 2020

Theoretically, benzodiazepines (BZDs) can narrow the iridocorneal angle and induce acute angle-closure glaucoma (AACG). However, little evidence exists regarding this association.The objective of this...