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Ophthalmology General

hADSCs derived extracellular vesicles inhibit NLRP3inflammasome activation and dry eye.

Sep 07, 2020

The present study was set out to address the therapeutic efficacy of human adipose tissue stem cells derived extracellular vesicles (hADSC-Evs) in a mouse model of dry eye disease and to investigate t...

Enhanced closed eye neutrophil degranulation in dry eye disease.

Sep 07, 2020

Closed eye neutrophils have demonstrated increased prevalence in dry eye disease, but the phenotype and extent of activation of these cells has yet to be described.12 normal subjects and 12 subjects w...

Comparison of 2-Year Outcomes between Intravitreal Ranibizumab and Intravitreal Aflibercept for Diabetic Macular Edema with "Treat-and-Extend" Regimen-Its Usefulness and Problems.

Sep 07, 2020

To compare the effectiveness of intravitreal ranibizumab (IVR) and intravitreal aflibercept (IVA) performed with the treat-and-extend (TAE) regimen on eyes with diabetic macular edema (DME).This is a ...

Systemic alterations in leukocyte subsets and the protective role of NKT cells in the mouse model of diabetic retinopathy.

Sep 07, 2020

The involvement of leukocytes in the pathophysiology of DR has mostly examined the role of monocytes and neutrophils with little emphasis on other immune cell types. In this study, we determined the s...

Fufang Xueshuantong alleviates diabetic retinopathy by activating the PPAR signalling pathway and complement and coagulation cascades.

Sep 07, 2020

Fufang Xueshuantong (FXST) is a traditional Chinese patent medicine composed of Panax notoginseng (Burkill) F.H.Chen (Araliaceae), Salvia miltiorrhiza Bunge (Lamiaceae), Astragalus propinquus Schischk...

Lower Eyelid Horizontal Tightening in Prostaglandin Associated Periorbitopathy.

Sep 07, 2020

To determine the effect of chronic topical use of prostaglandin analogs for glaucoma on lower eyelid tension.A prospective case-control study was performed. Lower eyelid tension was measured in a grou...

An Evaluation Using Colored Doppler Ultrasonography of Central Retinal Artery Hemodynamics in the Healthy Eye in Individuals With Late Monocular Blindness.

Sep 07, 2020

Structural and functional changes occur in the brain after vision losses. The purpose of the present study was to investigate central retinal artery (CRA) hemodynamics in the healthy eye of individual...

Retinal changes in Alzheimer's disease- integrated prospects of imaging, functional and molecular advances.

Sep 07, 2020

Alzheimer's Disease (AD) is a devastating neurodegenerative disorder of the brain, clinically characterised by cognitive deficits that gradually worsen over time. There is, at present, no established ...

Using the West Midlands CONCERT to characterise regional incidence of acute-onset post cataract surgery endophthalmitis.

Sep 07, 2020

Whilst research and innovation is embedded within the UK's National Health Service (NHS) constitution, Doctors-in-training have little opportunity to contribute to designing, leading and recruiting in...

Cost-effectiveness of Autonomous Point-of-Care Diabetic Retinopathy Screening for Pediatric Patients With Diabetes.

Sep 07, 2020

Screening for diabetic retinopathy is recommended for children with type 1 diabetes (T1D) and type 2 diabetes (T2D), yet screening rates remain low. Point-of-care diabetic retinopathy screening using ...

Glaucoma and Intraocular Pressure

Sep 04, 2020

Intraocular pressure (IOP) refers to the fluid pressure inside the eye and is an essential aspect in the evaluation of patients at risk of glaucoma. But the prevalence of glaucoma associated with the ...

Application of graphene nanowalls in an intraocular pressure sensor.

Sep 03, 2020

As the second leading cause of blindness in the world, glaucoma is mainly caused by persistent high intraocular pressure (IOP) that compresses the optic nerve and causes permanent damage. Noninvasive ...

Diagnostic Markers in Ocular Sarcoidosis in A High TB Endemic Population - A Multicentre Study.

Sep 03, 2020

To look at markers to differentiate ocular sarcoidosis from ocular tuberculosis in a high TB endemic population.Retrospective multicenter study involving seven tertiary eyecare centers in India betwee...

Diabetes Induced Alterations in Murine Vitreous Proteome Are Mitigated by IL-6 Trans-Signaling Inhibition.

Sep 03, 2020

Diabetic retinopathy (DR) is a microvascular complication caused by prolonged hyperglycemia and characterized by leaky retinal vasculature and ischemia-induced angiogenesis. Vitreous humor is a gel-li...

Automatic Grading of Retinal Blood Vessel in Deep Retinal Image Diagnosis.

Sep 03, 2020

Automatic grading of retinal blood vessels from fundus image can be a useful tool for diagnosis, planning and treatment of eye. Automatic diagnosis of retinal images for early detection of glaucoma, s...

MiR-542-5p regulates the progression of diabetic retinopathy by targeting CARM1.

Sep 03, 2020

Diabetic retinopathy (DR), as the most frequent microvascular complication of diabetes mellitus (DM), causes vision loss and blindness in adults worldwide with increasing incidence. MicroRNAs (miRNAs)...

Research article miR-21-5p: A viable therapeutic strategy for regulating intraocular pressure.

Sep 03, 2020

Lowering intraocular pressure (IOP) is the most effective treatment of glaucoma, however most of the current available glaucoma drugs target a single molecule. MicroRNAs (miRNAs) are noncoding RNAs th...

Progression and Risk Factors of Nongeographic Atrophy

Sep 02, 2020

Nongeographic atrophy (NGA) refers to as the retinal pigment disturbances, including hyperpigmentation and hypopigmentation in CFPs. NGA can be caused in eyes treated with anti-vascular endothelial gr...

Gender Gap in Ophthalmology Conference Speakers

Sep 01, 2020

“Although the rates of women in medicine and ophthalmology are increasing, a gender gap still exists in senior positions, such as senior faculty, chairs of academic programs, and deans of medical sc...

Non-Physician Hospital CEO Cut after Participating in Surgery

Aug 31, 2020

Last week on Twitter I asked this question: The 130 (2.5%) of 5,213 respondents who said they would allow a CEO to make a skin incision highlight the unscientific nature of Twitter polls. Restr...

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