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Ophthalmology General

Prevalence and Risk Factors of Severe Dry Eye in Bangladesh-Based Factory Garment Workers.

Aug 31, 2020

This study sought to evaluate the prevalence of dry eye and meibomian gland dysfunction (MGD) and the associated factors of severe dry eye symptoms (SDES) among garments worker of Gazipur, Bangladesh....

Size of the associations between anticholinergic burden tool scores and adverse outcomes in older patients.

Aug 31, 2020

Background Several anticholinergic scales and equations to evaluate the anticholinergic burden have been previously created. Association of these instruments with the anticholinergic outcomes are usua...

Efficacy and tolerability of nortriptyline in the management of neuropathic corneal pain.

Aug 31, 2020

Neuropathic corneal pain (NCP) is a recently acknowledged disease entity. However, there is no consensus in potential treatment strategies, particularly in patients with a centralized component of pai...

Comparison of SDOCT Scan Types for Grading Disorganization of Retinal Inner Layers and Other Morphologic Features of Diabetic Macular Edema.

Aug 31, 2020

To assess grading reproducibility of disorganization of the retinal inner layers (DRIL) and other morphologic features of diabetic macular edema (DME) across spectral domain optical coherence tomograp...

Patterns and Determinants of Choroidal Thickness in a Multiethnic Asian Population: The Singapore Epidemiology of Eye Diseases Study.

Aug 31, 2020

To describe the distribution and determinants of choroidal thickness (CT) in participants in a population study based on spectral-domain optical coherence tomography (SD-OCT) measurements.Population-b...

Improved conjunctival microcirculation in diabetic retinopathy patients with MTHFR polymorphisms after Ocufolin™ Administration.

Aug 31, 2020

To investigate conjunctival microvascular responses in patients with mild diabetic retinopathy (MDR) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms (D+PM) after administration of Ocufol...

Blindness Following Carotid Artery Stenting Due to Ocular Hyperperfusion - Report and Review of Literature.

Aug 31, 2020

Cerebral hyperperfusion syndrome is a well-recognised phenomenon following carotid revascularisation. It is defined as cerebral blood flow increase of more than 100% of the baseline. A similar phenome...

RNA-Seq analysis of differentially expressed genes of Staphylococcus epidermidis isolated from postoperative endophthalmitis and the healthy conjunctiva.

Aug 31, 2020

Staphylococcus epidermidis (S. epidermidis) is one of the primary pathogens in postoperative endophthalmitis, which is a devastating complication of cataract surgery and often results in irreversible ...

The X-linked retinopathies: Physiological insights, pathogenic mechanisms, phenotypic features and novel therapies.

Aug 31, 2020

X-linked retinopathies represent a significant proportion of monogenic retinal disease. They include progressive and stationary conditions, with and without syndromic features. Many are X-linked reces...

Retinal Manifestations of Idiopathic Intracranial Hypertension.

Aug 31, 2020

Case series and systematic review to understand significant retinal changes in patients with idiopathic intracranial hypertension (IIH) using fundus photography and optical coherence tomography (OCT)....

Alpha-crystallin mutations alter lens metabolites in mouse models of human cataracts.

Aug 27, 2020

Cataracts are a major cause of blindness worldwide and commonly occur in individuals over 70 years old. Cataracts can also appear earlier in life due to genetic mutations. The lens proteins, αA- and ...

Reproduction Function in Male Patients with Bardet Biedl Syndrome.

Aug 27, 2020

Bardet-Biedl syndrome (BBS) is a ciliopathy with a wide spectrum of symptoms due to primary cilia dysfunction including genitourinary developmental anomalies as well as impaired reproduction particula...

Long non-coding RNA MEG3 promotes cataractogenesis by upregulating TP53INP1 expression in age-related cataract.

Aug 27, 2020

Age-related cataract (ARC) is the leading cause of visual impairment or even blindness among the aged population globally. Long non-coding RNA (LncRNA) has been proven to be the potential regulator of...

Do Head-Mounted Augmented Reality Devices Affect Muscle Activity and Eye Strain of Utility Workers Who Do Procedural Work? Studies of Operators and Manhole Workers.

Aug 27, 2020

The objective was to determine the effect of two head-mounted display (HMD) augmented reality (AR) devices on muscle activity and eye strain of electric utility workers. The AR devices were the Micros...

Study of Factors Influencing Dry Eye in Rheumatoid Arthritis.

Aug 27, 2020

The present study investigated the relationship between dry eye and the disease activity in patients with rheumatoid arthritis (RA).Patients with RA were divided by the Ocular Surface Disease Index (O...

Prevalence of symptomatic dry eye in breast cancer patients undergoing systemic adjuvant treatment: A cross-sectional study.

Aug 27, 2020

To investigate the prevalence of symptomatic dry eye (SDE) on women undergoing systemic adjuvant therapy for breast cancer and its association with treatment settings.Woman undergoing breast cancer sy...

A comparative evaluation of segmental analysis of macular layers in patients with early glaucoma, ocular hypertension, and healthy eyes.

Aug 27, 2020

To compare macular layer thicknesses between early glaucoma, ocular hypertension, and healthy eyes and to evaluate the accuracy of spectralis optical coherence tomography (OCT) segmentation software i...

Optogenetic Stimulation of Cholinergic Amacrine Cells Improves Capillary Blood Flow in Diabetic Retinopathy.

Aug 27, 2020

Disruption in blood supply to active retinal circuits is the earliest hallmark of diabetic retinopathy (DR) and has been primarily attributed to vascular deficiency. However, accumulating evidence sup...

Inflammatory cells proliferate in the choroid and retina without choroidal thickness change in early Type 1 diabetes.

Aug 27, 2020

Increasing evidence points to inflammation as a key factor in the pathogenesis of diabetic retinopathy (DR). Choroidal inflammatory changes in diabetes have been reported and in vivo choroidal thickne...

Cost-Related Medication Non-Adherence in a Nationally Representative U.S. Population with Self-Reported Glaucoma.

Aug 27, 2020

To determine the rates of cost-related non-adherence to medications among U.S. adults with glaucoma and to determine if participants with glaucoma have more cost-related medication non-adherence than ...

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