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Ophthalmology General

A custom-made vitreoretinal surgical simulator using a silicone mold.

Jul 17, 2023

We constructed a custom-made vitreoretinal surgical simulator using a silicone mold and described its practicality.We obtained spherical silicone molds, mannequins, and spray material from an internet...

Full-field stimulus threshold testing: a scoping review of current practice.

Jul 17, 2023

The full-field stimulus threshold (FST) is a psychophysical measure of whole-field retinal light sensitivity. It can assess residual visual function in patients with severe retinal disease and is incr...

Full-field stimulus threshold testing: a scoping review of current practice.

Jul 17, 2023

The full-field stimulus threshold (FST) is a psychophysical measure of whole-field retinal light sensitivity. It can assess residual visual function in patients with severe retinal disease and is incr...

Towards modifying the genetic predisposition for glaucoma: An overview of the contribution and interaction of genetic and environmental factors.

Jul 10, 2023

Glaucoma, the leading cause of irreversible blindness worldwide, is a complex human disease, with both genetic and environmental determinants. The availability of large-scale, population-based cohorts...

Changes in intraocular lens explantation indications and comparison of various explantation techniques.

Jul 10, 2023

To examine the current causes of intraocular lens (IOL) explantation, compare various IOL explantation techniques, and assess the visual outcomes and complications.Retrospective comparative case serie...

Impact of text contrast polarity on the retinal activity in myopes and emmetropes using modified pattern ERG.

Jul 10, 2023

Environmental factors favoring myopia development are still being studied and there is accumulating evidence for a significant role of nearwork. Recently, reading standard black-on-white text was foun...

Meibomian gland stem/progenitor cells: The hunt for gland renewal.

Jul 10, 2023

Meibomian glands (MGs) secrete lipid (meibum) onto the ocular surface to form the outermost layer of the tear film. Proper meibum secretion is essential for stabilizing the tear film, reducing aqueous...

Meibomian gland stem/progenitor cells: The hunt for gland renewal.

Jul 10, 2023

Meibomian glands (MGs) secrete lipid (meibum) onto the ocular surface to form the outermost layer of the tear film. Proper meibum secretion is essential for stabilizing the tear film, reducing aqueous...

Effects of elevated serum estrogen on dry eye in women undergoing in vitro fertilisation.

Jul 10, 2023

Sex hormones impact inflammatory and immune-mediated diseases. During IVF (in vitro fertilisation) treatment, circulating estrogen levels increase dramatically (10-50x) alongside changes in other horm...

Effects of elevated serum estrogen on dry eye in women undergoing in vitro fertilisation.

Jul 10, 2023

Sex hormones impact inflammatory and immune-mediated diseases. During IVF (in vitro fertilisation) treatment, circulating estrogen levels increase dramatically (10-50x) alongside changes in other horm...

The effect of GLP-1 receptor agonist lixisenatide on experimental diabetic retinopathy.

Jul 10, 2023

Glucagon-like peptide-1 receptor agonists are effective treatments for type 2 diabetes, effectively lowering glucose without weight gain and with low risk for hypoglycemia. However, their influence on...

Persistence of severe global inequalities in the burden of blindness and vision loss from 1990 to 2019: findings from the Global Burden of Disease Study 2019.

Jul 10, 2023

To assess the global burden and economic inequalities in the distribution of blindness and vision loss between 1990 and 2019.A secondary analysis of the Global Burden of Diseases, Injuries and Risk Fa...

Association between contrast sensitivity function and structural damage in primary open-angle glaucoma.

Jul 10, 2023

To evaluate the association between contrast sensitivity function (CSF) and glaucomatous structural damage in primary open-angle glaucoma (POAG).A cross-sectional study was performed with 103 patients...

Managing primary open-angle glaucoma in the setting of suboptimal surgical outcomes in the fellow eye.

Jul 03, 2023

A 62-year-old woman with mild myopia presented to her local optometrist for a routine examination and was found to have intraocular pressure (IOP) of 30 mm Hg in both eyes and cupped nerves. She had a...

Managing primary open-angle glaucoma in the setting of suboptimal surgical outcomes in the fellow eye.

Jul 03, 2023

A 62-year-old woman with mild myopia presented to her local optometrist for a routine examination and was found to have intraocular pressure (IOP) of 30 mm Hg in both eyes and cupped nerves. She had a...

Optical changes and association with axial elongation in children wearing orthokeratology lenses of different back optic zone diameter.

Jul 03, 2023

To compare changes in ocular aberrations in children wearing orthokeratology (ortho-k) lenses with a back optic zone diameter (BOZD) of 6 mm (6-MM group) or 5 mm (5-MM group) and their associations ...

Optical changes and association with axial elongation in children wearing orthokeratology lenses of different back optic zone diameter.

Jul 03, 2023

To compare changes in ocular aberrations in children wearing orthokeratology (ortho-k) lenses with a back optic zone diameter (BOZD) of 6 mm (6-MM group) or 5 mm (5-MM group) and their associations ...

1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface.

Jul 03, 2023

Pseudognaphalium affine (P. affine), a medicinal plant, has long been used to treat various diseases due to its astringent and vulnerary effects. These therapeutic benefits are largely attributed to h...

1,5-Dicaffeoylquinic acid from Pseudognaphalium affine ameliorates dry eye disease via suppression of inflammation and protection of the ocular surface.

Jul 03, 2023

Pseudognaphalium affine (P. affine), a medicinal plant, has long been used to treat various diseases due to its astringent and vulnerary effects. These therapeutic benefits are largely attributed to h...

Interferon-γ elicits the ocular surface pathology mimicking dry eye through direct modulation of resident corneal cells.

Jul 03, 2023

Despite accumulating evidence indicating a key role of interferon-γ (IFN-γ)-producing immune cells in ocular infection and immunity, little is known about the direct effects of IFN-γ on resident co...

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