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Ophthalmology General

Intravitreal anti-vascular endothelial growth factor injections in pregnancy and breastfeeding: a case series and systematic review of the literature.

Nov 20, 2023

Anti-vascular endothelial growth factor (anti-VEGF) agents may occasionally need to be considered for sight-threatening macular pathology in pregnant and breastfeeding women. This is controversial due...

Developing screening tools to estimate the risk of diabetic kidney disease in patients with type 2 diabetes mellitus.

Nov 20, 2023

Diabetic kidney disease (DKD) is an important microvascular complication of diabetes mellitus (DM).This study aimed to develop predictive nomograms to estimate the risk of DKD in patients with type 2 ...

Nationwide analysis of neuromyelitis optica in systemic lupus erythematosus and Sjogren's syndrome.

Nov 20, 2023

Neuromyelitis optica (NMO), also known as Devic's disease, is a rare inflammatory demyelinating disorder causing myelitis and optic neuritis. While there have been reports of systemic lupus erythemato...

Potency of teleophthalmology as a detection tool for diabetic retinopathy.

Nov 13, 2023

In China, the prevalence of diabetic retinopathy (DR) is increasing, so it is necessary to provide convenient and effective community outreach screening programs for DR, especially in rural and remote...

Advances in mesenchymal stem cell-derived extracellular vesicles therapy for Sjogren's syndrome-related dry eye disease.

Nov 13, 2023

Sjogren's syndrome (SS) is a chronic autoimmune disorder that affects exocrine glands, particularly lacrimal glands, leading to dry eye disease (DED). DED is a common ocular surface disease that affec...

Intraocular cetuximab: Safety and effect on axial elongation in young Guinea pigs with lens-induced myopization.

Nov 13, 2023

This study aimed to examine the intraocular tolerability of the epidermal growth factor receptor antibody cetuximab, when applied intravitreally, and its effect on axial elongation. Guinea pigs aged 2...

The corneal biomechanical differences after wearing orthokeratology lenses and multifocal soft lenses in children: A self-control study.

Nov 13, 2023

To compare the changes in corneal biomechanics after orthokeratology (OK) lens and Defocus Incorporated Soft Contact (DISC) lens treatment.Of 28 myopic children were recruited, with one eye wearing OK...

Platelet-rich plasma for treating dry eye disease - A systematic review and meta-analysis.

Nov 13, 2023

Dry eye disease has public health and economic significance. Platelet-rich plasma is rich in anti-inflammatory agents and growth factors, both beneficial for ocular surface repair. This study aimed to...

Association of ocular surface and meibomian gland alterations with silicone hydrogel contact lens wear.

Nov 13, 2023

To evaluate silicone hydrogel contact lens (SH-CL) effects on the meibomian glands, corneal structure, and ocular surface parameters.Fifty SH-CL wearers for at least 6 months, and 50 sex and age-matc...

Predicting OCT biological marker localization from weak annotations.

Nov 13, 2023

Recent developments in deep learning have shown success in accurately predicting the location of biological markers in Optical Coherence Tomography (OCT) volumes of patients with Age-Related Macular D...

Primary Open Angle Glaucoma Diagnosis Using Pattern Electroretinogram Parameters.

Nov 13, 2023

Glaucoma is the most typical cause of permanent blindness. POAG, or primary open angle glaucoma, is the most common type. The pattern electroretinogram (PERG) has become a promising technique for dete...

The changes and causes of asthenopia after ICL implantation.

Nov 06, 2023

To detect the presence of asthenopia after implantation of Implantable Collamer Lens (ICL).Design: prospective observational case series. Patients with myopia and/or astigmatism who underwent ICL surg...

Potential benefits of Malva sylvestris in dry-eye disease pathology in vitro based on antioxidant, wound-healing and anti-inflammatory properties.

Nov 06, 2023

Dry eye disease (DED) is a common chronic ocular surface disease. Available therapies are effective but often associated with side effects. This study investigates the potential of a Malva sylvestris ...

Intravitreal Aflibercept for the Treatment of Diabetic Macular Edema in Routine Clinical Practice: Results from the 24-Month AURIGA Observational Study.

Nov 06, 2023

AURIGA is the largest real-world study to date to evaluate intravitreal aflibercept (IVT-AFL) in the treatment of diabetic macular edema (DME) or macular edema secondary to retinal vein occlusion in r...

MiR-423-5p promotes Müller cell activation via targeting NGF signaling in diabetic retinopathy.

Nov 06, 2023

Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus and one of the major causes of visual impairment and blindness in industrialized countries. The early neuro-glial ...

Scleromalacia perforans as an early manifestation of late-onset rheumatoid arthritis: a case-based review.

Nov 06, 2023

Rheumatoid arthritis is a chronic autoimmune disease that can affect different organs beyond the joints. Ocular involvement includes keratoconjunctivitis sicca, peripheral ulcerative keratitis (PUK), ...

Complementary and Alternative Medicine Use Among Patients with Dry Eye Syndrome in Saudi Arabia: A Survey Study.

Nov 06, 2023

Complementary and alternative medicine (CAM) includes all healthcare practices that are not part of conventional medicine. One of the most common eye disorders for visiting an ophthalmology clinic is ...

Single fraction and hypofractionated radiosurgery for perioptic meningiomas-tumor control and visual outcomes: a systematic review and meta-analysis.

Oct 30, 2023

Perioptic meningiomas, defined as those that are less than 3 mm from the optic apparatus, are challenging to treat with stereotactic radiosurgery (SRS). Tumor control must be weighed against the risk...

Cost-effectiveness analysis of prophylactic laser peripheral iridotomy for primary angle-closure suspect in Japan.

Oct 30, 2023

This study aimed to compare the cost-effectiveness of prophylactic laser peripheral iridotomy (LPI) with that of observation for primary angle-closure suspect (PACS) in Japan.A Markov model was develo...

Six-year cumulative treatment effect and treatment efficacy of a dual focus myopia control contact lens.

Oct 30, 2023

Accumulated axial growth observed during a 6-year clinical trial of a dual focus myopia control contact lens was used to explore different approaches to assess treatment efficacy.Axial length measurem...

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