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Orthopedics General

Metformin reverses impaired osteogenesis due to hyperglycemia-induced neutrophil extracellular traps formation.

Sep 04, 2023

Diabetic patients suffer from delayed fracture healing and impaired osteogenic function, but the underlying pathophysiological mechanisms are not fully understood. Neutrophil extracellular traps (NETs...

Indices for the brittleness of pharmaceutical tablets: a reassessment.

Sep 04, 2023

Brittleness is an important mechanical property. In the classical sense, a material is considered brittle if, during loading, it behaves elastically until failure. Nevertheless, it is also sometimes u...

Functional Hypothalamic Amenorrhea: Recognition and Management of a Challenging Diagnosis.

Sep 04, 2023

Functional hypothalamic amenorrhea is responsible for approximately a third of the cases of secondary amenorrhea. The condition is a result of disturbances in gonadotropin-releasing hormone pulsatile ...

Influence of stem design parameters on periprosthetic femoral fractures examined by subject specific finite element analyses.

Aug 28, 2023

Due to the increasing number of periprosthetic femoral fractures (PFF), the optimisation of implant design gains importance. For the presented research a validated, subject specific finite element mod...

The role of the depth of resection of the distal tibia on biomechanical performance of the tibial component for TAR: A finite element analysis with three implant designs.

Aug 28, 2023

The depth of resection of the tibia bone in total ankle replacement (TAR) may influence implant-bone micromotion and stress shielding. High implant-bone micromotion and stress-shielding lead to asepti...

Analysis and multiple index evaluation of SPO distribution of bone traction needles for pelvic fracture reduction.

Aug 28, 2023

For robot-assisted pelvic fracture reduction, at least two bone needles need to be inserted into the ilium of the affected pelvis, and the robot clamping device is connected with the bone needles. The...

Hip fracture surgery performed by cadaveric simulation-trained versus standard-trained orthopaedic trainees: a preliminary multicentre randomized controlled trial.

Aug 21, 2023

To evaluate if, for orthopaedic trainees, additional cadaveric simulation training or standard training alone yields superior radiological and clinical outcomes in patients undergoing dynamic hip scre...

Assessing the risk of re-fracture related to the percentage of partial union in scaphoid waist fractures.

Aug 21, 2023

There is ambiguity surrounding the degree of scaphoid union required to safely allow mobilization following scaphoid waist fracture. Premature mobilization could lead to refracture, but late mobilizat...

"Geriatric Proximal Humerus Fracture Operative Management: A TRUVEN Health Analytics Database Study (2015-2020)".

Aug 14, 2023

The purpose of this study is to assess the trends in operative management of geriatric (≥65 years) proximal humerus fractures during a six-year period (2015-2020) within an insurance claims database...

Understanding Exercise Capacity - from Elite Athlete to HFpEF.

Aug 14, 2023

Exercise capacity is a spectrum which reflects an individual's functional capacity and the dynamic nature of cardiac remodeling along with respiratory and skeletal muscle systems. The relationship bet...

Bone-Targeted Delivery of Cell-Penetrating-RUNX2 Fusion Protein in Osteoporosis Model.

Aug 14, 2023

The onset of osteoporosis leads to a gradual decrease in bone density due to an imbalance between bone formation and resorption. To achieve optimal drug efficacy with minimal side effects, targeted dr...

Amenorrhea and oligomenorrhea risk related to exercise training volume and intensity: Findings from 3705 participants recruited via the STRAVA™ exercise application.

Aug 07, 2023

To investigate associations between self-reported exercise training habits and amenorrhea/oligomenorrhea among physically active women.A cross-sectional survey was completed by 3705 women (median age�...

A rare find of a maxillary third molar with five roots: a case report of an unusual morphology.

Jul 31, 2023

Third molars are frequently absent or impacted; their unpredictable prevalence and morphology, with frequent anatomical variations, is a challenge for the practitioner. The number of roots of the uppe...

Immediate loading of dental implants in edentulous mandibles using Locator attachments or Dolder bars: A 9-year prospective randomized clinical study.

Jul 31, 2023

To evaluate the long-term survival, incidence of prosthetic/technical and biological complications and the oral-health-related quality of life in patients with an edentulous mandible who were fitted w...

Otosclerosis under the magnifying glass.

Jul 31, 2023

Otosclerosis is a bone condition affecting the stapes bone within the otic capsule, and its exact cause is still unknown. It is characterized by a lack of proper remodeling of newly formed vascular an...

Experience of an Anatomic Femoral Stem in a United Kingdom Center - Excellent Survivorship and Negligible Periprosthetic Fracture Rates at Mean 12 years Following Primary Total Hip Arthroplasty.

Jul 17, 2023

As the clinical burden of peri-prosthetic fractures (PPFs) continues to increase, it has been suggested that the use of anatomical femoral stems may help reduce PPF risk. The primary aim of this study...

Revision risk of unipolar and bipolar hemiarthroplasties in the Dutch Arthroplasty Register.

Jul 17, 2023

Hemiarthroplasty (HA) for hip fractures can be performed with an unipolar or bipolar head.We describe the use of unipolar and bipolar HA after a hip fracture in the Netherlands and determined revision...

Revision risk of unipolar and bipolar hemiarthroplasties in the Dutch Arthroplasty Register.

Jul 17, 2023

Hemiarthroplasty (HA) for hip fractures can be performed with an unipolar or bipolar head.We describe the use of unipolar and bipolar HA after a hip fracture in the Netherlands and determined revision...

Effect of Temperatures on Cyclic Fatigue Resistance of 3 Different Ni-Ti Alloy Files.

Jul 10, 2023

The aim of this study was to investigate and compare the effect of temperature on the cyclic fatigue resistance of conventional (ProTaper Universal [PTU]), Gold-Wire (ProTaper Gold [PTG]), and Fire-Wi...

Upper extremity physical performance tests in female overhead athletes: a test-retest reliability study.

Jul 10, 2023

Despite the studies that have investigated the reliability of Upper Extremity Functional Tests(UEFTs), the reliability of Closed Kinetic Chain Upper Extremity Stability(CKCUES), Seated Medicine Ball T...

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