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Orthopedics General

Bushenhuoxue formula accelerates fracture healing via upregulation of TGF-β/Smad2 signaling in mesenchymal progenitor cells.

Jun 15, 2020

Although Bushenhuoxue formula (BSHXF) is successfully used as a non-traumatic therapy in treating bone fracture in China, the molecular mechanism underlying its effects remains poorly understood.The p...

Avoiding iatrogenic injuries to the vertebral artery: A morphometric study of the vertebral artery-free dissection area.

Jun 15, 2020

To determine the area of a safety window that excludes the vertebral artery for the safe access of the occipital condyle screws during occipitocervical fixation.This study included 138 cervical comput...

Development of a preliminary multivariable diagnostic prediction model for identifying active spondylolysis in young athletes with low back pain.

Jun 15, 2020

The primary aim of this study was to develop a diagnostic cluster of common clinical findings that would assist in ruling out an active spondylolysis in adolescent athletes with low back pain (LBP).Re...

Comparison of Costs and Postoperative Outcomes between Vertebroplasty and Kyphoplasty for Osteoporotic Vertebral Compression Fractures: Analysis from a State-Level Outpatient Database.

Jun 15, 2020

Vertebral cement augmentation techniques are routinely employed to treat osteoporotic vertebral compression fractures (VCF). In the current study, we employed a state-level outpatient database to comp...

Update of Markov Model on the Cost-Effectiveness of Nonpharmacologic Interventions for Chronic Low Back Pain Compared to Usual Care.

Jun 11, 2020

Markov model.Further validity test of a previously published model.The previous model was built using data from ten randomized trials and examined the one-year effectiveness and cost-effectiveness of ...

Muscle fibre conduction velocity in the vastus lateralis and medialis muscles of soccer players after ACL reconstruction.

Jun 11, 2020

The neural factors underlying the persistency of quadriceps weakness after anterior cruciate ligament reconstruction (ACLR) have been only partially explained. This study examined muscle fiber conduct...

Locoregional recurrence rate and disease-specific survival following marginal vs segmental resection for oral squamous cell carcinoma with mandibular bone invasion.

Jun 11, 2020

To determine locoregional recurrence rate (LRR) and disease-specific survival (DSS) following marginal vs segmental mandibulectomy.Included were 210 patients, who had marginal or segmental mandibulect...

Analysis of low-level laser transmission at wavelengths 660, 830 and 904 nm in biological tissue samples.

Jun 11, 2020

In recent decades, low-level laser therapy (LLLT) has occupied a prominent position and has been studied in various fields of knowledge, and your effects have been widely observed in studies about num...

How Useful Are Tumor Markers in Detecting Metastases with FDG-PET/CT during Breast Cancer Surveillance?

Jun 11, 2020

To assess the clinical usefulness of serum tumor markers for early detection of distant breast cancer recurrence using FDG-PET/CT.We retrospectively analyzed 561 consecutive patients who underwent sur...

DHEA in bone: the role in osteoporosis and fracture healing.

Jun 08, 2020

Dehydroepiandrosterone (DHEA) is a metabolic intermediate in the biosynthesis of estrogens and androgens with a past clouded in controversy and bold claims. It was once touted as a wonder drug, a foun...

Evaluation of facet joints and segmental motion in patients with different grades of L5/S1 intervertebral disc degeneration: a kinematic MRI study.

Jun 08, 2020

This study aimed to evaluate facet joint parameters and osteoarthritis grades, and segmental angular and translational motions among different grades of L5/S1 intervertebral disc (IVD) degeneration.Th...

Injuries to the Head and Face From Skateboarding: A 10-Year Analysis From National Electronic Injury Surveillance System Hospitals.

Jun 08, 2020

To estimate the incidence of patients presenting to emergency departments (EDs) as a result of facial trauma sustained from skateboarding.The National Electronic Injury Surveillance System (NEISS) dat...

Sickle cell disease clinical phenotypes in Nigeria: A preliminary analysis of the Sickle Pan Africa Research Consortium Nigeria database.

Jun 08, 2020

Sickle cell disease (SCD) is a monogenic disease with multiple phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria were localized, with limited data, hence the need ...

Biomechanical comparison of anterior cruciate ligament repair with internal brace augmentation versus anterior cruciate ligament repair without augmentation.

Jun 08, 2020

Newer repair techniques of anterior cruciate ligament tears, including augmentation with internal brace, have shown promising clinical results. Few biomechanical studies exist comparing anterior cruci...

Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in MEF2D-fusion (+) ALL cells.

Jun 08, 2020

MEF2D-fusion (M-fusion) genes are newly discovered recurrent gene abnormalities that are detected in approximately 5 % of acute lymphoblastic leukemia (ALL) cases. Their introduction to cells has been...

Minimum clinically important difference of major patient-reported outcome measures in patients undergoing decompression surgery for lumbar spinal stenosis.

Jun 04, 2020

A minimum clinically important difference (MCID) has been increasingly well known in the current era of patient-centered care because it reflects a smallest change that is meaningful for patients foll...

The Effect of Divided Attention with Bounce Drop Jump on Dynamic Postural Stability.

Jun 04, 2020

This study determined the effect of divided attention on controlling postural stability during a drop vertical jump task. In total, 30 participants were tested for drop vertical jumps from a 30-cm hig...

A comparative study of materials assembled from recombinant K31 and K81 and extracted human hair keratins.

Jun 04, 2020

Natural biopolymers have found success in tissue engineering and regenerative medicine applications. Their intrinsic biocompatibility and biological activity make them well suited for biomaterials dev...

Associations between Proton Pump Inhibitor and Histamine-2 Receptor Antagonist and Bone Mineral Density among Kidney Transplant Recipients.

Jun 04, 2020

In the general population, use of proton pump inhibitor (PPI) has been linked to higher risk of osteoporotic fractures. PPI is commonly prescribed in kidney transplant recipients (KTRs). However, the ...

Stem cell mobilization with plerixafor and healing of diabetic ischemic wounds: A phase IIa, randomized, double-blind, placebo-controlled trial.

Jun 04, 2020

Bone marrow-derived cells contribute to tissue repair, but traffic of hematopoietic stem/progenitor cells (HSPCs) is impaired in diabetes. We therefore tested whether HSPC mobilization with the CXCR4 ...

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