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Orthopedics

Effect of calcium phosphate and silk fibroin nanofibers tuning on properties of calcium sulfate bone cements.

Jul 23, 2020

Calcium sulfate (CS) bone cements have been used as bone substitutes for a long history, but it is limited to apply in clinical trials due to its rapid degradation rate and brittleness. This work aims...

Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome.

Jul 23, 2020

Gray platelet syndrome (GPS) is a rare recessive disorder caused by biallelic variants in NBEAL2 and characterized by bleeding symptoms, the absence of platelet ɑ-granules, splenomegaly and bone marr...

FeO/Bioactive glass nanostructure: A promising therapeutic platform for osteosarcoma treatment.

Jul 23, 2020

An effective strategy of hyperthermia-chemotherapy-regeneration for bone-related cancer treatments is presented. For this purpose, a new approach of magnetic particles (MPs) encapsulated in bioactive ...

Preprosthesis fracture of femoral and loosening of the femoral prosthesis during closed reduction of hip dislocation: A case report.

Jul 23, 2020

Dislocation after bipolar hip hemiarthroplasty is an uncommon complication. Although closed manoeuvre reduction under general anaesthesia is a common and effective method for dislocation of the hemiar...

Fragility fractures and health-related quality of life: does socio-economic status widen the gap? A population-based study.

Jul 20, 2020

Studying 12,839 fracture cases and 91,426 controls, we found that fractures of the spine and hip are associated with clinically important HRQoL deficits up to 5 years post-fracture. Fracture cases wi...

Bigger Necks Are Not Enough: An Examination of Neck Circumference in Incoming College Athletes.

Jul 20, 2020

Neck circumference is quick and simple to measure and thus an attractive proxy of neck strength, a putative mechanism underlying risk of sport-related concussion (SRC). Research, however, is limited o...

Efficacy of conservative therapy in older people with nonspecific low back pain: A systematic review with meta-analysis and GRADE recommendations.

Jul 20, 2020

This systematic review aimed to investigate the effectiveness of conservative therapy in older people with nonspecific low back pain.Searches were conducted on Medline, Amed, Embase, Cochrane, Psycinf...

Prognostic value of different metastatic sites for patients with FIGO stage IVB endometrial cancer after surgery: A SEER database analysis.

Jul 20, 2020

This study aimed to investigate the association between different metastatic sites and survival in endometrial cancer (EC) patients with International Federation of Gynecology and Obstetrics (FIGO) st...

Technical note: Efficient and accurate MRI-only based treatment planning of the prostate using bulk density assignment through atlas-based segmentation.

Jul 20, 2020

This study investigates the dosimetric accuracy as well as the robustness of a bulk density assignment approach to MRI-only based treatment planning of the prostate, with bulk density regions automati...

UPLC-MS metabolomics method provides valuable insights into the effect and underlying mechanisms of Rhizoma Drynariae protecting osteoporosis.

Jul 20, 2020

Osteoporosis (OP) is a metabolic bone disease in which that volume of bone tissue per unit volume decrease, which is a common disease disturbing the elderly or postmenopausal women. Rhizoma Drynariae ...

Clavicle Non-Union: Plate and Graft Type Do Not Affect Healing Rates - A Single Surgeon Experience With 71 Cases.

Jul 16, 2020

Clavicle non-unions often result after nonoperative treatment for the acute fracture. Those that require >1 surgical procedure in order for a nonunion to heal are termed recalcitrant. The aims of t...

Risk factors for hardware removal following operative treatment of middle and distal third clavicle fractures.

Jul 16, 2020

The incidence of hardware removal (HWR) after operative fixation of clavicle fractures varies widely. Risk factors related to HWR remain incompletely understood. The aim of this study was to evaluate ...

Motion-Onset Visual Potentials Evoked in a Sport-Specific Visuomotor Reaction Task.

Jul 16, 2020

Although neural visual processes play a crucial role in sport, experiments have been restricted to laboratory conditions lacking ecological validity. Therefore, this study examined the feasibility of ...

Rationale for Definitive Mini Dental Implant Treatment.

Jul 16, 2020

Mini dental implants can be used to support crowns and partial and complete dentures in compromised edentulous sites. Lack of bone width or site length may be treated with mini implants. Mini implants...

Classification, Categorization, and Algorithms for Articular Cartilage Defects.

Jul 16, 2020

There is a critical unmet need in the clinical implementation of valid preventative and therapeutic strategies for patients with articular cartilage pathology based on the significant gap in understan...

Estimation of [177Lu]PSMA-617 tumor uptake based on voxel-wise 3D Monte Carlo tumor dosimetry in patients with metastasized castration resistant prostate cancer.

Jul 16, 2020

 Patients with advanced prostate cancer are suitable candidates for [Lu]PSMA-617 therapy. Integrated SPECT/CT systems have the potential to improve the accuracy of patient-specific tumor dosimetry. ...

Burden of musculoskeletal disorders in Iran during 1990-2017: estimates from the Global Burden of Disease Study 2017.

Jul 13, 2020

Musculoskeletal diseases (MSDs) are the leading cause of disability and facing them demands updated reports on their burden for efficient policymaking. We showed Iran had the highest female-to-male ra...

Effect of Botulinum Toxin Type A on Mandibular Fracture Healing: An Experimental Study in Rabbits.

Jul 13, 2020

The effect of botulinum toxin type A (BTX-A) on fracture healing of the long bones is controversial, and no controlled clinical or experimental study has investigated the effect of BTX-A on mandibular...

Patient Preferences for Osteoarthritis Pain and Chronic Low Back Pain Treatments in the United States: A Discrete-Choice Experiment.

Jul 13, 2020

To quantify preferences for attributes of potential analgesic treatments for moderate-to-severe pain associated with osteoarthritis (OA) and/or chronic low back pain (CLBP) as relevant to injectable n...

Sotrastaurin, a PKC inhibitor, attenuates RANKL-induced bone resorption and attenuates osteochondral pathologies associated with the development of OA.

Jul 13, 2020

Osteoarthritis (OA) is a common degenerative disease that affects the musculoskeletal structure of the whole joint, which is characterized by progressive destruction of both articular cartilage and su...

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