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Pain General

Short and Mid-Term Predictors of Response to OnabotulinumtoxinA: Real-Life Experience Observational Study.

Feb 25, 2020

To identify clinical predictors of excellent response to OnabotulinumtoxinA in patients with chronic migraine (CM) at 6 and 12 months of follow-up.Clinical predictors of response to Onabotulinumtoxin...

The impact of external trigeminal nerve stimulator (e-TNS) on prevention and acute treatment of episodic and chronic migraine: A systematic review.

Feb 25, 2020

The aim of this systematic review was to analyze the effectiveness and safety of the external trigeminal nerve stimulator (eTNS) for the prevention and acute treatment of migraine attacks in episodic ...

Framingham Risk Stratification of Middle-Aged Migraineurs.

Feb 25, 2020

. Migraine is a common primary headache disorder involving about 10-15% of the whole population. Several epidemiological and prospective studies showed a link between migraine (especially migraine wit...

SMN gene copy number analysis by exome-seq: assisting SMA diagnosis and carrier screening.

Feb 25, 2020

Spinal muscular atrophy (SMA) is a leading genetic cause of infant death, influenced by the copy number of two highly-homologous genes: SMN1 and SMN2. Although exome-seq is widely applied for genetic ...

Detecting Migration and Infiltration of Neutrophils in Mice.

Feb 25, 2020

Neutrophils are a major member of the innate immune system and play pivotal roles in host defense against pathogens and pathologic inflammatory reactions. Neutrophils can be recruited to inflammation ...

Ultrasound verified enthesophytes are associated with radiographic progression at entheses in psoriatic arthritis.

Feb 25, 2020

The aim of this prospective study was to examine whether ultrasound or clinical abnormalities at enthesal sites predict radiographic progression at entheses in psoriatic arthritis (PsA).Consecutive Ps...

Phytol, a Chlorophyll Component, Produces Antihyperalgesic, Anti-inflammatory, and Antiarthritic Effects: Possible NFκB Pathway Involvement and Reduced Levels of the Proinflammatory Cytokines TNF-α and IL-6.

Feb 25, 2020

Phytol is a diterpene constituent of chlorophyll and has been shown to have several pharmacological properties, particularly in relation to the management of painful inflammatory diseases. Arthritis i...

Contribution of COMT and BDNF Genotype and Expression to the Risk of Transition from Acute to Chronic Low Back Pain.

Feb 25, 2020

A number of factors, including heritability and the environment, contribute to risk of transition from acute low back pain (ALBP) to chronic low back pain (CLBP). The aim of this study was to A) compa...

The Influence of a Positive Empathetic Interaction on Conditioned Pain Modulation and Manipulation Induced Analgesia in People with Lateral Epicondylalgia.

Feb 25, 2020

Conditioned pain modulation (CPM) and manipulation induced analgesia (MIA) are two forms of endogenous analgesia. Many forms of analgesia can be influenced by the nature of the patient clinician inter...

Effect on Opioids Requirement of Early Administration of Intranasal Ketamine for Acute Traumatic Pain.

Feb 25, 2020

To evaluate the efficacy and safety of early administration of low-dose intranasal ketamine on reducing the need for opioid and non-opioid analgesic agents in emergency department (ED) patients with a...

Pain-related Self-efficacy Among People with Back Pain: A Systematic Review of Assessment Tools.

Feb 25, 2020

Before an intervention can be implemented to improve pain-related self-efficacy, assessment is required. The aim of the present study was to provide a systematic review on which self-efficacy scales a...

Hypervigilance for Bodily Sensations in the Back During a Movement Task in People with Chronic and Recurrent Low Back Pain.

Feb 25, 2020

The current study assessed the role of hypervigilance for bodily sensations in the back in long term low back pain (LBP) problems.People with chronic low back pain (CLBP), recurrent low back pain (RLB...

How does the joint Dermatology-Rheumatology clinic benefit both patients and Dermatologists?

Feb 25, 2020

Psoriasis (Pso) and psoriatic arthritis (PsA) are chronic and debilitating diseases which often develop in the same patient and are linked to a wide range of comorbid conditions. Dermatologists and Rh...

Impact of fatigue on health-related quality of life and illness perception in a monocentric cohort of patients with systemic lupus erythematosus.

Feb 25, 2020

Fatigue is a very common and debilitating symptom in patients with systemic lupus erythematosus (SLE), even among those with a mild or inactive disease. The objective of this study is to define fatigu...

Effects of a functional training programme in patients with Fibromyalgia: A 9-years prospective longitudinal cohort study.

Feb 25, 2020

There are evidences that physical exercise is an effective instrument for improving physical fitness, health and quality of life and causes beneficial effects on the symptoms of patients with fibromya...

Bioinformatics analysis of gene and microRNA targets for fibromyalgia.

Feb 25, 2020

Fibromyalgia (FM) is the most common chronic pain disease in middle-aged women. Patients may also complain of migraine, irritable bowel syndrome and depression, which seriously affect their work and l...

Activation of Transposable Elements in Immune Cells of Fibromyalgia Patients.

Feb 25, 2020

Advancements in nucleic acid sequencing technology combined with an unprecedented availability of metadata have revealed that 45% of the human genome constituted by transposable elements (TEs) is not ...

Association between lower back pain and lower extremity pain among young volleyball players: A cross-sectional study.

Feb 25, 2020

Lower back pain (LBP), as well as lower extremity injuries, are major problems among young volleyball players. Nevertheless, only few studies have focused on the relationship between lower extremity i...

Investigation of the Effect of Secreted Factors from Mesenchymal Stem Cells on Disc Cells from Degenerated Discs.

Feb 25, 2020

Low back pain is experienced by a large number of people in western countries and may be caused and influenced by many different pathologies and psychosocial factors including disc degeneration. Disc ...

Primary culture of mouse adipose and fibrous synovial fibroblasts under normoxic and hypoxic conditions.

Feb 25, 2020

Synovial fibroblasts have attracted considerable attention in studies of joint diseases. Although mice are useful and powerful in in vitro and in vivo experiments, primary cultures of mouse synovial f...

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