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Pain General

Assessing Prescription Analgesic Use in Older Adults With CKD

Jan 05, 2021

Opioids and NSAIDs are the most commonly used analgesics for managing pain in patients with chronic kidney disease (CKD), but these therapies come with important risks. “NSAIDs have direct nephrotox...

Efficacy and Safety Profile of Rectus Sheath Block in Adult Laparoscopic Surgery: A Meta-analysis.

Jan 04, 2021

Rectus sheath block (RSB) has been increasingly used for pain management after laparoscopic procedures but with a conflicting data on its analgesic efficacy. We conducted a systematic review and meta-...

Management of migraine in the emergency department: Findings from the 2010-2017 National Hospital Ambulatory Medical Care Surveys.

Jan 04, 2021

The study objective was to describe trends in the medical management of migraine in the emergency department (ED) using the 2010-2017 National Hospital Ambulatory Medical Care Survey (NHAMCS) datasets...

Vestibular migraine of childhood and recurrent vertigo of childhood: Diagnostic criteria consensus document of the committee for the classification of vestibular disorders of the bárány society and the international headache society.

Jan 04, 2021

This paper describes the diagnostic criteria for "Vestibular Migraine of Childhood", "probable Vestibular Migraine of Childhood" and "Recurrent Vertigo of Childhood" as put forth by the Committee for ...

The prevalence of psychiatric and chronic pain comorbidities in fibromyalgia: An acttion systematic review.

Jan 04, 2021

Fibromyalgia (FM) is a chronic widespread pain condition that overlaps with multiple comorbid health conditions and contributes to considerable patient distress. The aim of this review was to provide ...

Novel tankyrase inhibitors suppress TDP-43 aggregate formation.

Jan 04, 2021

Transactive response DNA-binding protein of 43 kDa (TDP-43) abnormally forms aggregates in certain subtypes of frontotemporal lobar degeneration (FTLD) and in amyotrophic lateral sclerosis (ALS). The...

Impact of a shelter-in-place order during the COVID-19 pandemic on the incidence of opioid overdoses.

Jan 04, 2021

Since the beginning of the novel coronavirus (COVID-19) pandemic in the United States, there have been concerns about the potential impact of the pandemic on persons with opioid use disorder. Shelter-...

Barriers and facilitators to PDMP IS Success in the US: A systematic review.

Jan 04, 2021

Prescription Drug Monitoring Programs (PDMP) help prevent prescription drug misuse and promote appropriate pain management. Despite these benefits and PDMP mandates in most states, PDMPs face challeng...

Type 1 helper T cells generate CXCL9/10-producing T-bet effector B cells potentially involved in the pathogenesis of rheumatoid arthritis.

Jan 04, 2021

Efficacy of B-cell depletion therapy highlights the antibody-independent effector functions of B cells in rheumatoid arthritis (RA). Given type 1 helper T (Th1) cells abundant in synovial fluid (SF) o...

How can neighborhood environments facilitate management of osteoarthritis: A scoping review.

Jan 04, 2021

The association between neighborhood environments and health outcomes has long been recognized, but the importance of environmental factors is less well examined in osteoarthritis (OA). We aimed to gi...

Association of interleukin-17 gene polymorphisms with the onset of Rheumatoid Arthritis.

Jan 04, 2021

Rheumatoid Arthritis (RA) is an autoimmune disorder where multiple cytokines including IL-17A and IL-17F produced by T helper cell 17 (Th17), contribute to its pathogenesis. By initiating inflammatory...

Application of the OMERACT synovitis ultrasound scoring system in juvenile idiopathic arthritis: a multicenter reliability exercise.

Dec 31, 2020

To evaluate the reliability of the OMERACT paediatric ultrasound (US) synovitis definitions and scoring system in JIA.Thirteen sonographers analysed 75 images for the presence/absence of elementary le...

Measuring complications of serious pediatric emergencies using ICD-10.

Dec 31, 2020

To create definitions for complications for 16 serious pediatric conditions using the International Classification of Diseases, 10th Revision, Clinical Modification or Procedure Coding System (ICD-10-...

Stepped Exercise Program for Patients With Knee Osteoarthritis : A Randomized Controlled Trial.

Dec 31, 2020

Evidence-based models are needed to deliver exercise-related services for knee osteoarthritis efficiently and according to patient needsTo examine a stepped exercise program for patients with knee ost...

Yishen-tongbi decoction inhibits excessive activation of B cells by activating the FcγRIIb/Lyn/SHP-1 pathway and attenuates the inflammatory response in CIA rats.

Dec 31, 2020

Rheumatoid arthritis (RA) is a chronic autoimmune disease. Strong evidence supports that excessive activation of B cells plays a critical role in the pathogenesis of RA. Fc gamma receptor b (FcγRIIb)...

Opioid-Induced Respiratory Depression in Pediatric Palliative Care Patients with Severe Neurological Impairment-A Scoping Literature Review and Case Reports.

Dec 31, 2020

Pediatric Palliative Care (PPC) addresses children, adolescents, and young adults with a broad spectrum of underlying diseases. A substantial proportion of these patients have irreversible conditions ...

Novel synthetic treatment options for migraine.

Dec 31, 2020

: Migraine is one of the most common neurological disorders. Nowadays, the 5-HT receptor agonists, namely triptans, are considered as the standard of care for migraine acute treatment. However, tripta...

Muscle Fascia Changes in Patients with Occipital Neuralgia, Headache, or Migraine.

Dec 31, 2020

In an ongoing effort to understand the pathogenesis of occipital neuralgia/headache/migraine, it is critical to describe the anatomical/tissue changes encountered during surgery. Greater occipital ner...

Orthostatic Headache in Children Including Postural Tachycardia Syndrome and Orthostatic Hypotension: A Near-Infrared Spectroscopy Study.

Dec 31, 2020

Although head and/or neck pain attributed to orthostatic hypotension is included in international guidelines, its mechanisms and relevance remain unknown. This study examined the term's relevance and ...

Clustering fibromyalgia patients: A combination of psychosocial and somatic factors leads to resilient coping in a subgroup of fibromyalgia patients.

Dec 31, 2020

Coping strategies and their efficacy vary greatly in patients suffering from fibromyalgia syndrome (FMS).We aimed to identify somatic and psychosocial factors that might contribute to different coping...

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