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Migraine

Pain Severity and Psychosocial Quality of Life in Adolescents with Migraine and Tension-Type Headache: Mediation by Perceived Expressed Emotion and Self-Esteem.

Mar 18, 2021

To investigate perceived expressed emotion (EE) and self-esteem in adolescents with primary headaches and to assess the psychologic factors, especially perceived EE, that may play a mediating role in ...

Partial and non responders to onabotulinumtoxinA can benefit from anti-CGRP monoclonal preventive treatment: a real-world evidence study.

Mar 18, 2021

Monoclonal antibodies targeting CGRP or its receptor (anti-CGRP mAbs) are proven to be effective treatments in migraine prevention. Real-world evidence studies assessing their efficacy are scarce.Our ...

Vestibular drop attacks in Ménière's disease.

Mar 04, 2021

The aim of the present study was to evaluate the severity of vestibular drop attack (VDA) in Ménière's disease (MD) and to examine the association between VDA severity and other MD-related complaint...

Brain glycogen metabolism: A possible link between sleep disturbances, headache and depression.

Feb 25, 2021

The functions of sleep and its links with neuropsychiatric diseases have long been questioned. Among the numerous hypotheses on sleep function, early studies proposed that sleep helps to replenish gly...

Treatment of headache disorders with acupuncture: a 6-year retrospective study.

Feb 25, 2021

Existing systematic reviews and meta-analyses indicate that acupuncture has similar clinical effectiveness in the prevention of headache disorders (HDs) as drug therapy, but with fewer side effects. A...

Anatomical variations of the foramen transversarium of cervical vertebrae from the ancient population of Herculaneum (79 CE; Naples, Italy).

Feb 25, 2021

Variations in the number, size and shape of the foramina transversaria of cervical vertebrae can affect the anatomical course of vital blood vessels and nerves, with the risk for pathological conditio...

Between and within-woman differences in the association between menstruation and migraine days.

Feb 22, 2021

To investigate between and within-woman differences in the association between menstruation and migraine days.Prior diary studies have shown that at the population level, aggregating across individual...

Ubrogepant for the Acute Treatment of Migraine: Pooled Efficacy, Safety, and Tolerability From the ACHIEVE I and ACHIEVE II Phase 3 Randomized Trials.

Feb 22, 2021

Ubrogepant is an oral, small-molecule calcitonin gene-related peptide receptor antagonist approved for the acute treatment of migraine. The efficacy and safety of ubrogepant were demonstrated in two p...

Dry Needling for the Treatment Of Tension-Type, Cervicogenic, or Migraine Headaches: a Systematic Review and Meta-Analysis.

Feb 22, 2021

Dry needling is a treatment technique used by clinicians to relieve symptoms in patients with tension-type headache (TTH), cervicogenic headache (CGH), or migraine. This systematic review's main objec...

Onabotulinumtoxin A Improves Psychological Aspects in Chronic Migraine Patients.

Feb 18, 2021

Chronic migraine (CM) affects 5.4% of the Kuwaiti population. It is associated with significant headache-related disability, psychiatric comorbidity and reduced quality of life. The aim of this study...

Enhanced Hemodynamic and Clinical Response to αCGRP in Migraine Patients-A TCD Study.

Feb 18, 2021

Sensitisation of the nervous system in a patient with migraine is supposed to be associated with calcitonin gene-related peptide (CGRP) activity. Therefore, the vascular response to human αCGRP (hα...

Real world effectiveness and tolerability of candesartan in the treatment of migraine: a retrospective cohort study.

Feb 18, 2021

To date, two randomized, controlled studies support the use of candesartan for migraine prophylaxis but with limited external validity. We aim to evaluate the effectiveness and tolerability of candesa...

A patient perspective of complementary and integrative medicine (CIM) for migraine treatment: a social media survey.

Feb 15, 2021

To survey persons with migraine who use social media about Complementary and Integrative Medicine (CIM) for the treatment of migraine.CIM encompasses medical treatments that are not part of but are us...

Pooled Analysis of PFO Occluder Device Trials in Patients With PFO and Migraine.

Feb 15, 2021

Although observational studies have shown percutaneous patent foramen ovale (PFO) closure to be a safe means of reducing the frequency and duration of migraine, randomized clinical trials have not met...

Genetics Influences Drug Consumption in Medication Overuse Headache, Not in Migraine: Evidence From Wolframin His611Arg Polymorphism Analysis.

Feb 11, 2021

The Wolframin His611Arg polymorphism can influence drug consumption in psychiatric patients with impulsive addictive behavior. This cross-sectional study aims to assess the prevalence of the Wolframi...

Effect of comorbid migraine on propranolol efficacy for painful TMD in a randomized controlled trial.

Feb 11, 2021

The migraine-preventive drug propranolol is efficacious in reducing pain from temporomandibular disorder, suggesting potential modifying or mediating effects of comorbid migraine.In this randomized co...

Muscle endurance and cervical electromyographic activity during submaximal efforts in women with and without migraine.

Feb 11, 2021

Despite previous reports supporting cervical muscle weakness and altered motor control in migraine, the endurance under standardized submaximal loads has not been investigated. Therefore, this study a...

Erenumab for the preventive treatment of chronic migraine complicated with medication overuse headache: an observational, retrospective, 12-month real-life study.

Feb 08, 2021

Erenumab is a monoclonal antibody blocking the calcitonin gene-related peptide receptor, which has been approved for the preventive treatment of chronic migraine (CM). The aim of this study was to exp...

Real-world efficacy, tolerability, and safety of ubrogepant.

Feb 08, 2021

To assess the real-world efficacy, tolerability, and safety of ubrogepant in a tertiary headache center.The efficacy and safety of ubrogepant for the acute treatment of migraine were established in ph...

Consensus among musculoskeletal experts for the management of patients with headache by physiotherapists? A delphi study.

Feb 08, 2021

Though a large amount of research on the management of headache has been conducted, the clinical effectiveness of these treatments remains unclear.To reach consensus among international musculoskeleta...