Erenumab in Chronic Migraine: An Australian Experience.
To determine the effectiveness and safety of erenumab in patients with chronic migraine in the real-world setting of 3 headache centers in Australia.Patients with migraine were prescribed er...
Migraine/Headache
Authoritative medical articles, news, research, and guidelines pertaining to Migraine/Headache.
Brain Metabolism and Structure in Chronic Migraine.
The purpose of this paper is to review and synthesize current literature in which neurochemical and structural brain imaging were used to investigate chronic migraine (CM) pathophysiology an...
Evaluation of Patients with Insufficient Efficacy and/or Tolerability to Triptans for the Acute Treatment of Migraine: A Systematic Literature Review.
Use of triptans for acute treatment of migraine is associated with insufficient efficacy and/or tolerability in approximately 30-40% of people. We conducted a systematic literature review (S...
Medication Overuse Withdrawal in Children and Adolescents Does Not Always Improve Headache: A Cross-Sectional Study.
MOH can be diagnosed in subjects with headache occurring 15 days/month in association with a regular medication overuse, but its existence is not universally accepted. ICHD-3 redefined crit...
Drug-naïve Egyptian females with migraine are more prone to sexual dysfunction than those with tension-type headache: a cross-sectional comparative study.
Headache is one of the chronic disorders that can trigger sexual dysfunction due to complex mechanisms. This study recruited 120 consecutive patients from our outpatient clinics with migrain...
Sumatriptan alleviates radiation-induced oral mucositis in rats by inhibition of NF-kB and ERK activation, prevention of TNF-α and ROS release.
Oral mucositis caused by radiation therapy is a common problem in cancer patients, especially those with head and neck cancer. Numerous experimental and clinical studies have attempted to fi...
Pain, Motivation, Migraine, and the Microbiome: New Frontiers for Opioid Systems and Disease.
For decades the broad role of opioids in addiction, neuropsychiatric disorders, and pain states has been somewhat well established. However, in recent years, with the rise of technological a...
Hypersensitivity to Calcitonin Gene-Related Peptide in Post-Traumatic Headache.
To demonstrate that calcitonin gene-related peptide (CGRP) induces headache exacerbation with migraine-like features in patients with persistent post-traumatic headache (PTH) attributed to m...
Case Report: Neurocysticercosis Acquired in Australia.
Neurocysticercosis (NCC) is a disease caused by infection of the central nervous system with the larval stage of the tapeworm This disease is endemic in many parts of the world, including A...
Functional impairment and disability among patients with migraine: evaluation of galcanezumab in a long-term, open-label study.
Migraine can negatively impact patient functioning and quality of life. Here, we report the effects of galcanezumab (GMB), a humanized monoclonal antibody that binds to calcitonin gene-relat...
Effect of Migraine on Pregnancy Planning: Insights From the American Registry for Migraine Research.
To evaluate the effect of migraine on women's pregnancy plans.Participants were enrolled in the American Registry for Migraine Research, an observational study that recruits patients from he...
Zinc supplementation affects favorably the frequency of migraine attacks: a double-blind randomized placebo-controlled clinical trial.
Observational studies have shown a link between zinc deficiency and migraine headaches. We aimed to examine the effect of zinc supplementation on the characteristics of migraine attacks in p...
Efficacy of patent foramen ovale closure for treating migraine: a prospective follow-up study.
This study aims to evaluate the potential of percutaneous patent foramen ovale (PFO) closure to improve the headache in patients with migraine and PFO, and discuss the difference between the...
Profiling the Extent and Location of Pain in Migraine and Cervicogenic Headache: A Cross-sectional Single-Site Observational Study.
The primary aim was to quantify and compare the location and extent of pain in people with either episodic migraine, chronic migraine, or cervicogenic headache. A secondary aim was to examin...
Transcranial Doppler Evaluation of the Cerebral Vasculature in Women Patients who Have Migraine with Aura.
Previous studies suggest that increased cerebrovascular reactivity might be a feature of patients who have migraine with aura (MwA). The correlation between the clinical presentation of migr...
Patterns of Perceived Stress Throughout the Migraine Cycle: A Longitudinal Cohort Study Using Daily Prospective Diary Data.
To describe patterns of perceived stress across stages of the migraine cycle, within and between individuals and migraine episodes as defined for this study.Individuals with migraine aged �...
[Novel migraine treatment with CGRP-related monoclonal antibodies].
Migraine is a common and debilitating neurological disorder characterized by recurrent attacks of moderate to severe throbbing headache accompanied by nausea, vomiting and photophobia/phonop...
Hemorrhagic reversible cerebral vasoconstriction syndrome: A retrospective observational study.
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by recurrent thunderclap headaches associated with segmental vasoconstriction of cerebral arteries, which may result in ...
Characteristics of Post-Ictal Headaches in Patients with Epilepsy: a Longitudinal Study.
This study aimed to investigate the clinical predictors of post-ictal headache (PIH) in patients with epilepsy in a tertiary center in Brazil.302 individuals with adult-onset epilepsy were f...
Predicting the outcome of the greater occipital nerve block - an observational study on migraine patients with and without musculoskeletal cervical impairment.
The importance of neck pain and the trigeminocervical complex in migraine is of high pathophysiological interest since a block to the greater occipital nerve is more effective for some prima...
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