In October 2021, many residents in Carson, California experienced malodors, headaches, and respiratory symptoms. Hydrogen sulfide (HS), a toxic odorous gas, was measured in Carson at concent...
Clinical heterogeneity may exist within asthma subtypes defined by inflammatory markers. However, the heterogeneity of neutrophilic asthma (NA) remains largely unexplored.To explore potentia...
Climate change has increased the frequency of extreme weather events and compounded natural disasters. Heat, wildfires, flooding and pollen are already threatening public health and dispropo...
This study examined the associations between attention-deficit/hyperactivity disorder (ADHD) symptoms, underperception of respiratory compromise, and illness representations in Black and Lat...
The use of dexamethasone to control equine asthma is a common and effective treatment. Although short-term systemic dexamethasone treatment has not been shown to induce systemic immunosuppre...
Severe asthma is a difficult-to-treat chronic airway inflammatory disease requiring systemic corticosteroids to achieve asthma control. It has recently been shown that drugs targeting immuno...
Airway smooth muscle (ASM) cells attain a hypercontractile phenotype during obstructive airway diseases. We recently identified a biased M3 muscarinic acetylcholine receptor (mAChR) ligand, ...
Our study aimed to quantitatively estimate the association of age at menarche with the risk of childhood- and adult-onset asthma separately.A retrospective cohort study of 24,282 US girls an...
Fritillaria unibracteata is an endangered medicinal plant whose bulb has been used as a Chinese herb to suppress cough, asthma and excessive phlegm for centuries. Steroidal alkaloids, which ...
Sanguisorba officinalis L. (S. officinalis L.), known as Di Yu (DY) in Traditional Chinese Medicine (TCM), are used to treat burns, vomiting of blood, asthma, intestinal infections, and derm...
Shikonin, the primary active compound found in the rhizome of the traditional Chinese medicinal herb known as "ZiCao", exhibits a diverse range of pharmacological effects. This drug has a wi...
There is a clinical need to understand the etiologies of periodontitis, considering the growing socio-economic impact of the disease. Despite recent advances in oral tissue engineering, expe...
There have been no investigations of longitudinal asthma trajectories based on asthma exacerbation frequency and medications required for asthma control in children.To investigate the longit...
FEV1 improved significantly at 12 weeks in patients treated with fluticasone furoate plus vilanterol compared with monotherapy, with no new safety issues. Philippe Bareille presented...
Growing up on traditional European, and U.S. Amish, dairy farms, in close contact with cows and hay, protects children against asthma, and airway administration of extracts from dust collect...
EQTM (expression quantitative trait methylation) analyses uncover associations between DNA methylation markers and gene expression. Most eQTM analyses of complex diseases have focused on cis...
Biological therapies, such as mepolizumab and benralizumab, offer treatment options for severe eosinophilic asthma (SEA), although long-term real-world data on their use are limited.Evaluate...
The Global Initiative for Asthma (GINA) and National Asthma Education and Prevention Program (NAEPP) recently made paradigm-shifting recommendations regarding inhaler management in asthma. G...
Allergic diseases typically begin in early life and can impose a heavy burden on children and their families. Effective preventive measures are currently unavailable but may be ushered in by...
Asthma is a heterogeneous disease in which the complexity of the breathing pattern reduces as the severity of the disease increases. Since the pathophysiological basis of reduced breathing p...
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