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Asthma

Post Infectious Bronchiolitis Obliterans Masked by Misdiagnosis as Asthma

Feb 13, 2020

Asthma and postinfectious bronchiolitis obliterans (PIBO) have similar clinical findings, and PIBO may be misdiagnosed with asthma. This study aimed to determine the clinical features of PIBO in child...

Hotspot detection and socio-ecological factor analysis of asthma hospitalization rate in Guangxi, China.

Feb 13, 2020

Asthma is a major public health concern throughout the world. Numerous researches have shown that the spatial-temporal patterns of asthma are inconsistent, leading to the suggestion that these pattern...

An inflammatory stimulus sensitizes TRPA1 channel to increase cytokine release in human lung fibroblasts.

Feb 13, 2020

External stimuli such as cigarette smoke and house dust mite are often involved in the development and exacerbation of asthma. These risk factors could activate or sensitize transient receptor potenti...

C1q/TNF-Related Protein-9 Alleviates Airway Inflammation in Asthma

Feb 13, 2020

Asthma is characterized as inflammatory disorder in the respiratory system with increasing tendency. Most of the asthma patients suffered from the disease since childhood. Thus, developing novel thera...

Tracheal relaxation through calcium channel blockade of Achillea millefolium hexanic extract and its main bioactive compounds.

Feb 10, 2020

L. (Asteraceae) is used for the treatment of respiratory diseases, diabetes, and hypertension.to explore its tracheal relaxant properties and clarify its functional mechanism of action on smooth muscl...

An endothelial microRNA-1-regulated network controls eosinophil trafficking in asthma and chronic rhinosinusitis.

Feb 10, 2020

Airway eosinophilia is a prominent feature of asthma and chronic rhinosinusitis (CRS), and the endothelium plays a key role in eosinophil trafficking. To date, microRNA-1 (miR-1) is the only microRNA ...

Exercise-induced Bronchoconstriction in Elite or Endurance Athletes

Feb 10, 2020

To review the pathogenesis and evaluation of exercise-induced bronchoconstriction pertaining to the elite or endurance athlete, as well as propose a diagnostic algorithm based on the current literatur...

Effects of dexamethasone on VEGF-induced MUC5AC expression in human primary bronchial epithelial cells: Implications for asthma.

Feb 10, 2020

Mucins are major macromolecular components of lung mucus that are mainly responsible for the viscoelastic property of mucus. MUC5AC is a major mucin glycoprotein that is hypersecreted in asthmatic ind...

Alopecia Areata is Associated with Atopic Diathesis; Results from a Population-Based Study of 51,561 Patients.

Feb 10, 2020

Evidence of Th1/interferon (IFN)γ over-activation as major pathogenic driver somewhat conflicts with data supporting robust allergic background in alopecia areata (AA) patients. Previous investigatio...

Soufeng Yuchuan decoction mitigates the ovalbumin-induced lung damage in a rat model of asthma.

Feb 10, 2020

Airway remodeling is a key feature of asthma. Extracellular matrix synthesis and vascular remodeling respectively regulated by transforming growth factor (TGF-β1) and vascular endothelial growth fact...

Effects of Hot Foot and Arm Bath in Bronchial Asthma

Feb 10, 2020

Managing the condition of corticosteroid resistant asthmatic patients is quite difficult and challenging despite the plethora of new and modern medications. Hot Foot and Arm Bath (HFAB) is a widely us...

Air Quality Index and air quality awareness among adults in the United States.

Feb 04, 2020

Information about local air quality is reported across the United States using air quality alerts such as the Environmental Protection Agency's Air Quality Index. However, the role of such alerts in r...

Long-term methylglyoxal intake aggravates murine Th2-mediated airway eosinophil infiltration.

Feb 04, 2020

Asthma outcomes is aggravated in obese patients. Excess of methylglyoxal (MGO) in obese/diabetic patients has been associated with diverse detrimental effects on cell function. This study aimed to eva...

Feasibility and clinical applications of multiple breath wash-out (MBW) testing using sulphur hexafluoride in adults with bronchial asthma.

Feb 04, 2020

Ventilation heterogeneity is frequent in bronchial asthma and can be assessed using multiple breath wash-out testing (MBW). Most data is available in paediatric patients and using nitrogen as a tracer...

Discovery of potential asthma targets based on the clinical efficacy of Traditional Chinese Medicine formulas.

Feb 04, 2020

Standard therapy for asthma, a highly heterogeneous disease, is primarily based on bronchodilators and immunosuppressive drugs, which confer short-term symptomatic relief but not a cure. It is difficu...

Special Considerations and Perspectives for EIB in Olympic Athletes

Feb 04, 2020

Diagnosing and treating elite and Olympic athletes with exercise-induced bronchoconstriction (EIB) has been well established. However, a sub-set of elite and Olympic athletes with exercise-induced bro...

Copaiba oil suppresses inflammation in asthmatic lungs of BALB/c mice induced with ovalbumin.

Feb 04, 2020

Asthma is a chronic inflammatory disease that represents high hospitalizations and deaths in world. Copaiba oil (CO) is popularly used for relieving asthma symptoms and has already been shown to be ef...

Rosuvastatin suppresses cytokine production and lung inflammation in asthmatic, hyperlipidemic and asthmatic-hyperlipidemic rat models.

Feb 04, 2020

Given the role that T lymphocytes play on the pathogenesis of allergic asthma, drugs targeting Th2 and Th17 cells may be a hopeful therapeutic strategy. This study aimed to evaluate the effect of rosu...

Inhibition of antigen-specific immune responses by co-application of an indoleamine 2,3-dioxygenase (IDO)-encoding vector requires antigen transgene expression focused on dendritic cells.

Feb 04, 2020

We have previously shown that particle-mediated epidermal delivery (PMED) of plasmids encoding β-galactosidase (βGal) under control of the fascin-1 promoter (pFascin-βGal) yielded selective product...

Maternal Obesity During Pregnancy Continues to Rise

Jan 31, 2020

The pandemic of obesity during pregnancy now afflicts 1 out of every 2 pregnant women in the United States. Even though unintended pregnancy has decreased to 45% of all pregnancies, 50% of those unint...

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