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Asthma

Real-Time Measurements of Gas-Phase Trichloramine (NCl) in an Indoor Aquatic Center.

May 27, 2021

NCl is formed as a disinfection byproduct in chlorinated swimming pools and can partition between the liquid and gas phases. Exposure to gas-phase NCl has been linked to asthma and can irritate the ey...

Effect of electro-acupuncture at ST 36 on maternal food restriction-induced lung phenotype in rat offspring.

May 27, 2021

Maternal food restriction (MFR) during pregnancy leads to pulmonary dysplasia in the newborn period and increases susceptibility to diseases, such as asthma and chronic lung disease, later in life. Pr...

Using Large Aggregated De-Identified Electronic Health Record Data to Determine the Prevalence of Common Chronic Diseases in Pediatric Patients Who Visited Primary Care Clinics.

May 24, 2021

We used de-identified clinical data from multiple healthcare systems using different electronic health records (EHRs) to 1) quantify the prevalence of common pediatric chronic diseases, 2) investigate...

Noninvasive Measurement of Pulmonary Function in Experimental Mouse Models of Airway Disease.

May 20, 2021

Mouse models have become an indispensable tool in translational research of human airway disease and have provided much of our understanding of the pathogenesis of airway disease such as asthma. In th...

VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway.

May 20, 2021

Mucus-secreting goblet cells are the dominant cell type in pulmonary diseases, e.g., asthma and cystic fibrosis (CF), leading to pathologic mucus metaplasia and airway obstruction. Cytokines including...

Differences in oral food challenge reaction severity based on increasing age in a pediatric population.

May 20, 2021

Food allergy (FA) reactions range from mild to severe with differences in age appearing to be an important factor associated with reaction severity.To define differences in oral food challenge (OFC) r...

Clinical-Epidemiological Characteristics of the First Patients Diagnosed with COVID-19 in Cuba.

May 13, 2021

COVID-19 is caused by the novel coronavirus SARS-CoV-2 and was declared a pandemic on March 11, 2020, the same day that the first cases in Cuba were diagnosed. In Cuba, all confirmed cases of COVID-19...

Implications of Low-grade Inflammation in SARS-CoV-2 Immunopathology.

May 13, 2021

Advanced age and chronic disease comorbidities are indicators of poor prognosis in COVID-19 clinical progression. Fatal outcomes in patients with these characteristics are due to a dysfunctional immun...

Asthma Remission Disparities among U.S. Youth by Sexual Identity and Race/Ethnicity, 2009-2017.

May 10, 2021

Sexual minority and racial/ethnic minority youth experience a higher burden of asthma. The frameworks of minority stress theory and intersectionality suggest sexual minority and racial/ethnic minority...

Highlights in the advances of chronic rhinosinusitis.

May 06, 2021

Chronic rhinosinusitis (CRS) is a complex upper airway inflammatory disease with a broad spectrum of clinical variants. As our understanding of the disease pathophysiology evolves, so too does our phi...

Self-reported adverse reactions to subcutaneous airborne allergen immunotherapy: a real-life, single center study.

May 06, 2021

To estimate the prevalence of self-reported adverse reactions (AdR) to subcutaneous airborne allergen immunotherapy (SCIT) and to describe factors associated with its occurrence. Real-life, observat...

Sedentary behavior is associated with chronic obstructive pulmonary disease: A generalized propensity score-weighted analysis.

May 06, 2021

Chronic obstructive pulmonary disease (COPD) is the fourth and third leading cause of death worldwide and in China, respectively. Sedentary behavior has been shown to increase the risk of respiratory ...

Infant Gut Microbiome Is Enriched with Bifidobacteria longumssp. infantisin Old Order Mennoniteswith Traditional Farming Lifestyle.

Apr 29, 2021

Growing up on traditional, single-family farms is associated with protection against asthma in school-age, but the mechanisms against early manifestations of atopic disease are largely unknown. We sou...

Biomarkers for predicting response to aspirin therapy in aspirin-exacerbated respiratory disease.

Apr 29, 2021

Aspirin desensitization followed by daily aspirin use is an effective treatment for aspirin-exacerbated respiratory disease (AERD).To assess clinical features as well as genetic, immune, cytological, ...

Physician's perspective regarding asthma guided self-management: directives or guidance?

Apr 22, 2021

Asthma guided self-management enhances patients' control of their condition under the guidance of the treating physician. The aim of the present study was to understand how physicians perceive, endors...

Oral inhalation for delivery of proteins and peptides to the lungs.

Apr 15, 2021

Oral inhalation is the preferred route for delivery of small molecules to the lungs, because high tissue levels can be achieved shortly after application. Biologics are mainly administered by intraven...

Distinct Patterns of Tissue Remodeling and Their Prognostic Role in Chronic Rhinosinusitis.

Apr 15, 2021

Tissue remodeling refers to structural changes that occur in damaged tissue and is associated with disease severity in asthma. However, the characteristics of tissue remodeling and its prognostic role...

Uptake of an Integrated Electronic Questionnaire System in Community Pediatric Clinics.

Apr 15, 2021

 The study aimed to evaluate an integrated electronic questionnaire system implementation in outpatient community pediatric practices on workflow, completion rates, and recorded scores. We evaluat...

Biology and therapeutic potential of human innate lymphoid cells.

Apr 12, 2021

In the last decade, innate lymphoid cells (ILCs) have become established as important players in different areas such as tissue homeostasis, integrity of mucosal barriers, and regulation of inflammati...

Respiratory Health, Pulmonary Function and Local Engagement in Urban Communities Near Oil Development.

Apr 05, 2021

Modern oil development frequently occurs in close proximity to human populations. Los Angeles, California is home to the largest urban oil field in the country with thousands of active oil and gas wel...

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