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Asthma

Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles.

Aug 31, 2020

The application of nanomedicines is increasing rapidly with the promise of targeted and efficient drug delivery. Nanomedicines address the shortcomings of conventional therapy, as evidenced by several...

Correlations of forced oscillometric bronchodilator response with airway inflammation and disease duration in asthma.

Aug 31, 2020

Airway resistance and reactance, measured by forced oscillometry, are used to measure airway obstruction in patients with asthma.This study aimed to investigate oscillometric bronchodilator responses ...

A Closer Look at Severe Asthma Over Time From Childhood

Aug 30, 2020

A study has found that about half of children diagnosed with severe asthma initially no longer had it after 3 years, and asthma severity decreased equally in both boys and girls over time. &nbs...

A Closer Look at Severe Asthma Over Time From Childhood

Aug 29, 2020

A study has found that about half of children diagnosed with severe asthma initially no longer had it after 3 years, and asthma severity decreased equally in both boys and girls over time. &nbs...

Common cold among young adults in China without a history of asthma or allergic rhinitis - associations with warmer climate zone, dampness and mould at home, and outdoor PM and PM.

Aug 27, 2020

This paper studied associations between reported common cold and home dampness and mould, cleaning habits and ventilation, climate and outdoor air pollution in China among young adults without asthma ...

Pediatric Asthma Healthcare Utilization, Viral Testing, and Air Pollution Changes during the COVID-19 Pandemic.

Aug 24, 2020

The COVID-19 pandemic caused dramatic changes in daily routines and healthcare utilization and delivery patterns in the United States. Understanding the influence of these changes and associated publi...

Temporal changes in short-term associations between cardiorespiratory emergency department visits and PM in Los Angeles, 2005 to 2016.

Aug 20, 2020

Emissions control programs targeting certain air pollution sources may alter PM composition, as well as the risk of adverse health outcomes associated with PM.We examined temporal changes in the risk ...

Impact of Social Determinants of Health on the Emerging COVID-19 Pandemic in the United States.

Aug 17, 2020

A novel coronavirus (2019-nCoV) caused a global pandemic in the months following the first four cases reported in Wuhan, China, on December 29, 2019. The elderly, immunocompromised, and those with pre...

Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait.

Aug 10, 2020

In Kuwait, prior to the first case of COVID-19 being reported in the country, mass screening of incoming travelers from countries with known outbreaks was performed and resulted in the first identifie...

Companion animals likely do not spread COVID-19 but may get infected themselves.

Aug 10, 2020

Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). From the epidemiological data, the pictu...

Bronchioalveolar stem cells in lung repair, regeneration and disease.

Aug 03, 2020

Bronchioalveolar stem cells (BASCs) are a lung resident stem cell population located at bronchioalveolar duct junctions that contribute to the maintenance of bronchiolar club cells and alveolar epithe...

Asthma-Related Health Outcomes Associated with Short-Acting β-Agonist Inhaler Use: An Observational UK Study as Part of the SABINA Global Program.

Jul 30, 2020

Patients with asthma typically increase short-acting β-agonists (SABA) use with worsening symptoms. Excessive SABA use may lead to a higher risk of adverse outcomes. We evaluated, in a large populati...

SABA Reliance Questionnaire (SRQ): identifying patient beliefs underpinning reliever over-reliance in asthma.

Jul 27, 2020

Patient over-reliance on short-acting beta agonists (SABA), with concomitant underuse of inhaled corticosteroids (ICS), is associated with poor asthma control and increased risk of asthma attacks.To d...

SNP-HLA Reference Consortium (SHLARC): HLA and SNP data sharing for promoting MHC-centric analyses in genomics.

Jul 20, 2020

Genome-wide associations studies have repeatedly identified the major histocompatibility complex genomic region (6p21.3) as key in immune pathologies. Researchers have also aimed to extend the biologi...

Quantifying continuous nebulization via high flow nasal cannula and large volume nebulizer in a pediatric model.

Jul 20, 2020

Use of high flow nasal cannula (HFNC) to deliver aerosolized medications to children has gained considerable interest. However, data on continuous albuterol delivery (CAD) via HFNC are lacking. This s...

Updates for the treatment of EGPA.

Jul 13, 2020

Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss syndrome) is the least frequent antineutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV). Major advances of our ...

Associations of IL-18 and IL-9 expressions and gene polymorphisms with asthma.

Jul 09, 2020

To explore the associations of interleukin-18 (IL-18) and IL-9 gene polymorphisms with susceptibility to asthma, and to study the associations between IL-18 and IL-9 expression levels and polymorphism...

Residence proximity to traffic-related facilities is associated with childhood asthma and rhinitis in Shandong, China.

Jul 09, 2020

Associations of asthma and rhinitis with residential traffic proximity were investigated in several studies, but conclusions were inconsistent. From January to April in 2015, a cross-sectional study w...

The β-adrenoceptor agonist bronchodilators terbutaline and orciprenaline are also weak α-adrenoceptor antagonists.

Jun 29, 2020

Recently, the β-adrenoceptor agonist terbutaline was shown to have α-adrenolytic activity in mouse isolated pulmonary arteries in vitro and to lower pulmonary artery pressure in anaesthetised mice. ...

Assessment of adherence to asthmacontrollers in children and adolescents.

Jun 25, 2020

Low adherence to asthma controllers is known to increase the risk of uncontrolled disease and poor health outcomes.We aimed to study risk factors of long-term adherence to preventive medications in ch...

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