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Vaccines

SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study.

Mar 25, 2021

Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.The primary outcome was the number...

Spatial analysis of vaccination against Hepatitis B in pregnant women in an urban Brazilian area.

Mar 18, 2021

The objective of this article is to analyze the spatial distribution of Hepatitis B vaccine (HBVAC) of pregnant women. This is a cross-sectional study carried with 266 puerperae. The HBVAC record was ...

VLP-factory™ and ADDomer : Self-assembling Virus-Like Particle (VLP) Technologies for Multiple Protein and Peptide Epitope Display.

Mar 18, 2021

Virus-like particles (VLPs) play a prominent role in vaccination as safe and highly versatile alternatives to attenuated or inactivated viruses or subunit vaccines. We present here two innovations, VL...

Human Papilloma Virus vaccine and prevention of head and neck cancer, what is the current evidence?

Mar 18, 2021

Human Papilloma Virus is associated with the development of cancers in the head and neck region. We have witnessed, in the last decades, an increase in number of cases directly related to HPV infectio...

Assessing Parent HPV Vaccine Reminders & Phone-Based Motivational Interviewing

Mar 01, 2021

Research shows that the HPV vaccine can prevent more than 31,000 cancer cases each year in the United States, but some states report that fewer than 50% of adolescents have initiated the HPV vaccine s...

Preparing for the Coronavirus Disease (COVID-19) Vaccination: Evidence, Plans, and Implications.

Feb 25, 2021

The formation of herd immunity through vaccination is a key point in overcoming the coronavirus disease 2019 (COVID-19) pandemic. To acquire herd immunity, a high vaccination rate is required, which i...

Acute and chronic inflammatory neuropathies and COVID-19 vaccines: practical recommendations from the task force of the Italian Peripheral Nervous System Association (ASNP).

Feb 25, 2021

to develop recommendations for vaccination for coronavirus-19 (COVID-19) in patients with inflammatory neuropathies.key questions were formulated in order to perform a literature review on the safety ...

Significant Declines in Juvenile Onset Recurrent Respiratory Papillomatosis following HPV Vaccine Introduction in the United States.

Feb 25, 2021

Juvenile onset recurrent respiratory papillomatosis (JORRP) is a rare and serious disease caused by human papillomavirus (HPV) presumably acquired during vaginal delivery. HPV vaccination of females t...

Influenza vaccine community outreach: Leveraging an interprofessional healthcare student workforce to immunize marginalized populations.

Feb 22, 2021

Vulnerable populations such as the uninsured, unemployed, and unhoused face significant morbidity and mortality from influenza but are less likely to receive the annual vaccine and have limited access...

Photochemical internalization (PCI)-mediated activation of CD8 T cells involves antigen uptake and CCR7-mediated transport by migratory dendritic cells to draining lymph nodes.

Feb 22, 2021

Antigen cross-presentation to cytotoxic CD8 T cells is crucial for the induction of anti-tumor and anti-viral immune responses. Recently, co-encapsulation of photosensitizers and antigens into microsp...

Glycosylation is required for the neutralizing activity of human IgG1 antibodies against human rabies induced by pre-exposure prophylaxis.

Feb 22, 2021

Rabies lyssavirus (RABV) neutralizing IgG antibodies confer protection after rabies vaccination, although how the RABV-specific antibodies neutralize the virus is still unknown. As changes in the anti...

[The lack of confidence to vaccination as information planting].

Feb 18, 2021

The key requirements to vaccine are its safety and efficiency. Nowadays, when issue of vaccination is extremely acute, certain citizens began voluntarily to refuse important procedure, not becoming th...

Estimated impact of the pneumococcal conjugate vaccine on pneumonia mortality in South Africa, 1999 through 2016: An ecological modelling study.

Feb 18, 2021

Data on the national-level impact of pneumococcal conjugate vaccine (PCV) introduction on mortality are lacking from Africa. PCV was introduced in South Africa in 2009. We estimated the impact of PCV ...

SLy2-overexpression impairs B-cell development in the bone marrow and the IgG response towards pneumococcal conjugate-vaccine.

Feb 18, 2021

Infections with Streptococcus pneumoniae can cause severe diseases in humans including pneumonia. Although guidelines for vaccination have been established, S. pneumoniae is still responsible for a se...

Endemic infections, vaccinations and variability of SARS-COV2 worldwide epidemiology: a cross-sectional study.

Feb 15, 2021

The present article aims to analyze epidemiologic aspects of the novel coronavirus pandemic (COVID-19) over different countries across the globe. While analyzing the overall spread of the disease, clu...

[Allergic reactions to COVID-19 vaccines: evidence and practice-oriented approach].

Feb 15, 2021

Less than a year after the first detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), vaccines have been approved for routine use in numerous countries and have already been used...

Evaluation of protection induced by in vitro maturated BMDCs presenting CD8 T cell stimulating peptides after a heterologous vaccination regimen in BALB/c model against Leishmania major.

Feb 15, 2021

Leishmaniasis is a complex vector-borne disease mediated by Leishmania parasite and a strong and long-lasting CD4 Th1 and CD8-T cell immunity is required to control the infection. Thus far multivalent...

Immunogenicity and Safety of Reduced-Dose Intradermal vs Intramuscular Influenza Vaccines: A Systematic Review and Meta-analysis.

Feb 11, 2021

Low-dose intradermal influenza vaccines could be a suitable alternative to full intramuscular dose during vaccine shortages.To compare the immunogenicity and safety of the influenza vaccine at reduced...

Evaluation of oral phytogenic microbeaded Newcastle Disease vaccine delivery in indigenous chicken.

Feb 11, 2021

This study describes the evaluation of microbeaded oral vaccine delivery for Newcastle Disease (ND) in village chicken. Microbeads containing vaccine were prepared by ionotropic-gelation technique usi...

Recombinant ArgF PLGA nanoparticles enhances BCG induced immune responses against Mycobacterium bovis infection.

Feb 11, 2021

Mycobacterium bovis (M. bovis) is a member of mycobacterium tuberculosis complex (MTBC), and a causative agent of chronic respiratory disease in a wide range of hosts. Bacillus Calmette-Guerin (BCG) v...

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