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Aging

Physical Frailty in COPD Can Predict Disability & Mortality

Jan 28, 2022

Research has shown that COPD is a disease with extra-pulmonary and systemic manifestations, including prominent muscle wasting, explains Tze Pin Ng, MD. “There is a growing recognition that the prog...

The Impact of Flu Vaccination on Survival for Elderly Men With COPD

Jan 24, 2022

Previous studies have established that patients aged 65 and older with COPD are at elevated risk for influenza-associated complications, such as hospitalization, ICU admissions, and death. Guidelines ...

Ketamine Associated Intraoperative Electroencephalographic Signatures of Elderly Patients With and Without Preoperative Cognitive Impairment.

Jan 24, 2022

Ketamine is typically used by anesthesiologists as an adjunct for general anesthesia and as a nonopioid analgesic. It has been explored for prevention of postoperative delirium, although results have ...

Air pollution as a risk factor for Cognitive Impairment no Dementia (CIND) and its progression to dementia: A longitudinal study.

Jan 17, 2022

Accumulation of evidence has raised concern regarding the harmful effect of air pollution on cognitive function, but results are diverging. We aimed to investigate the longitudinal association of long...

Association between sarcopenia and erectile dysfunction in older males.

Jan 10, 2022

In advanced age, both sarcopenia and erectile dysfunction (ED) occur with similar underlying causes through different mechanisms. In our study we investigated the association between sarcopenia and ED...

The CBL-LSD1-CXCL8 axis regulates methionine metabolism in glioma.

Jan 10, 2022

Gliomas are the most frequent type of brain tumors, with a high mortality rate and a lack of efficient targeted therapy. Methionine is an essential amino acid, and restriction of methionine in the die...

Predicting Superagers by Machine Learning Classification Based on the Functional Brain Connectome Using Resting-State Functional Magnetic Resonance Imaging.

Jan 03, 2022

Superagers are defined as older adults who have youthful memory performance comparable to that of middle-aged adults. Classifying superagers based on the brain connectome using machine learning modeli...

Sole Family Survivors: Older Adults Lacking Family of Origin Kin.

Jan 03, 2022

We introduced a unique form of kinlessness: sole family survivorship, which describes the lack of family of origin (i.e., biological parents and siblings) kin. This form of kinlessness may be particul...

Acute alcohol intoxication across different age groups in 2014-2018: Prehospital care and biochemical correlates at a large University Hospital in southern Italy.

Dec 27, 2021

Risky alcohol consumption can occur from a young age and affects people of all age groups, sometimes requiring the intervention of the emergency medical services.Determining the timing and characteris...

Potential Application of Low-Intensity Pulsed Ultrasound in Delaying Aging for Mice.

Dec 27, 2021

The low-intensity pulsed ultrasound (LIPUS) is one of the popular treatment modalities allowing to boost the proliferation, differentiation, and migratory activity of cells, which might be a powerful ...

[Influence of guided bone regeneration on marginal bone loss of implants in the mandible posterior region: a 10-year retrospective cohort study].

Dec 20, 2021

To investigate the effect of guided bone regeneration (GBR) on marginal bone loss (MBL) in the region of the mandibular posterior tooth by using a retrospective cohort study, in order to provide refe...

Mechanical characterization of dissected and dilated human ascending aorta using Fung-type hyperelastic models with pre-identified initial tangent moduli for low-stress distensibility.

Nov 22, 2021

Ascending aortic dissection (AD) is a potentially fatal vascular disease associated with degradation and fragmentation of the elastic fibers in the aortic media, increasing low-stress distensibility, ...

Age-related changes in event related potentials, steady state responses and temporal processing in the auditory cortex of mice with severe or mild hearing loss.

Nov 15, 2021

Age-related changes in auditory processing affect the quality of life of older adults with and without hearing loss. To distinguish between the effects of sensorineural hearing loss and aging on corti...

Long-term air pollution, noise, and structural measures of the Default Mode Network in the brain: Results from the 1000BRAINS cohort.

Nov 01, 2021

While evidence suggests that long-term air pollution (AP) and noise may adversely affect cognitive function, little is known about whether environmental exposures also promote structural changes in un...

Developing a person-centered, population based measure of "home time": Perspectives of older patients and unpaid caregivers.

Oct 25, 2021

Measuring "home time," number of days not in facility-based care, with medical claims is a promising approach to assess person-centered outcomes on a population level. Generally, spending more time at...

Age and sex differences in associations between self-reported health, physical function, mental function and mortality.

Oct 18, 2021

To explore how age and sex affect the impacts of self-rated health, self-reported physical activities, physical function, and depressive symptoms on long-term mortality among community-dwelling middle...

Telomerase-Positive Somatic Tissues of Honeybee Queens (Apis mellifera) Display No DNA Replication.

Oct 18, 2021

Telomere biology is closely linked to the process of aging. The restoration of telomere length by maintaining telome-rase activity in certain cell types of human adults allows for the proliferative ca...

Bronchiolar adenomas (BA) - A detailed radio-pathologic analysis of six cases and review of literature.

Oct 11, 2021

Bronchiolar adenomas (BAs)/ciliated muco-nodular papillary tumors (CMPTs), are small, peripheral lung nodules arising predominantly in the elderly that follow a benign course. They can be mistaken for...

Ghrelin, leptin and high-molecular-weight adiponectin in relation to depressive symptoms in older adults: Results from the Longitudinal Aging Study Amsterdam.

Oct 04, 2021

Ghrelin, leptin and high-molecular-weight (HMW) adiponectin have been linked to depression in middle-aged adults. Pathophysiological mechanisms of depression change as age progresses and it is unclear...

Psychometric Properties of the Lasher and Faulkender Anxiety about Aging Scale (AAS) among Iranian Older Adults.

Sep 27, 2021

(1) Background: The older adult population of society is exposed to multiple stressors daily, such as the loss of loved ones, dysfunctional mobility, financial dependence, and suffering from numerous ...