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Aging

Integrative Analysis of Long Non-Coding RNAs (lncRNAs), miRNAs, and mRNA-Associated ceRNA Network in Lung Tissue of Aging Mice and Changes After Treatment with Codonopsis pilosula.

Feb 13, 2020

BACKGROUND Codonopsis pilosula is a traditional Chinese medicine that has an anti-aging effect. However, the anti-aging effect of Codonopsis pilosula on the lungs remains largely unknown, and the mole...

Hemostasis in elderly patients with human immunodeficiency virus (HIV) infection-Cross-sectional study.

Feb 13, 2020

Aging and chronic HIV infection are clinical conditions that share the states of inflammation and hypercoagulability. The life expectancy of the world population has increased in the last decades, bri...

Parkinson's disease, aging and adult neurogenesis: Wnt/β-catenin signalling as the key to unlock the mystery of endogenous brain repair.

Feb 13, 2020

A common hallmark of age-dependent neurodegenerative diseases is an impairment of adult neurogenesis. Wingless-type mouse mammary tumor virus integration site (Wnt)/β-catenin (WβC) signalling is a v...

Outcome of elderly patients with classical Hodgkin's lymphoma.

Feb 13, 2020

The optimal management of elderly patients (pts) with Hodgkin's lymphoma is not yet defined. The aims of the present study were: 1) to evaluate clinical and laboratory characteristics of elderly pts; ...

Au nanozyme-driven antioxidation for preventing frailty.

Feb 10, 2020

From senescence and frailty that may result from various biological, mechanical, nutritional, and metabolic processes, the human body has its own antioxidant defense enzymes to remove by-products of o...

Impact of frailty in surgical emergencies. A comparison of four frailty scales.

Feb 10, 2020

Frailty is a geriatric syndrome, leading to declines in homeostatic reserve and physical resistance. It has been considered as a risk factor for falls, fractures, need of institutionalization, length ...

Aspergillus Flavus Malignant External Otitis in Diabetic Patient

Feb 10, 2020

Malignant external otitis is an aggressive and potentially life-threatening infection. This rare disorder is typically caused by Pseudomonas aeruginosa and affects almost exclusively elderly diabetic ...

Should radical surgery for rectal cancer be offered to elderly population? A propensity-matching analysis on short- and long-term outcomes.

Feb 10, 2020

Elderly patients with rectal tumor are often undertreated if compared to younger ones. The reasons for this attitude are not fully clear.The aim of this study was to determine the feasibility of radic...

The accuracy of the Geriatric Nutritional Risk Index in detecting frailty and sarcopenia in hospitalized older adults.

Feb 10, 2020

Malnutrition, sarcopenia, and frailty are prevalent conditions amongst hospitalized elderly. They are associated with numerous adverse health outcomes. The co-existence of these problems is common, wi...

Effect of antioxidants, mitochondrial cofactors and omega-3 fatty acids on telomere length and kinematic joint mobility in young and old shepherd dogs - A randomized, blinded and placebo-controlled study.

Jan 31, 2020

In dogs, decreasing telomere length is a biomarker for cellular aging. On a systemic level, aging affects the locomotor system in particular, leading to restricted joint mobility. As aging is thought ...

Aspects of the immune system that impact brain function.

Jan 31, 2020

The conditions required for effective immune responses to viral or bacterial organisms and chemicals of exogenous origin and to intrinsic molecules of abnormal configuration, are briefly outlined. Thi...

Behavior and distribution of polystyrene foams on the shore of Tuul River in Mongolia.

Jan 31, 2020

Foamed plastic debris in aquatic systems has become one of the emerging global contaminants. In this study, the behavior of polystyrene foam (PSF) and microplastics (MPs) adhered on the PSFs were inve...

Oral Anticoagulation in the Elderly and Frail.

Jan 31, 2020

The proportion of elderly patients will increase substantially over the next decades, and both atrial fibrillation (AF) and venous thromboembolism (VTE) are more common in the elderly. Age is a risk f...

The Learning Curve for Shared Decision-making in Symptomatic Aortic Stenosis.

Jan 30, 2020

Shared decision-making (SDM) is widely advocated for patients with valvular heart disease yet is not integrated into the heart team model for patients with symptomatic aortic stenosis. Decision aids (...

A novel water-in-oil emulsion with a lecithin-modified bentonite prevents skin damage from urban dust and cedar pollen.

Jan 30, 2020

Particulate matter (PM), such as air pollutants and pollens, are known to cause skin aging through skin inflammation. It is important to develop formulations which protect the skin from PM. We previou...

Lobule-Specific Dosage Considerations for Cerebellar Transcranial Direct Current Stimulation During Healthy Aging: A Computational Modeling Study Using Age-Specific Magnetic Resonance Imaging Templates.

Jan 30, 2020

Aging is associated with a decline in cognitive and motor performances, which are a part of geriatric syndromes. Since aging is associated with morphological changes in the cerebellum and cerebellar m...

Application of Rasch Analysis to the Evaluation of the Measurement Properties of the Hearing Handicap Inventory for the Elderly.

Jan 24, 2020

The aim of this research was to evaluate the measurement properties of the Hearing Handicap Inventory for the Elderly (HHIE). The HHIE is one of the most widely used patient-reported outcome measures ...

RIDGE-SHAPED MACULA IN YOUNG MYOPIC PATIENTS AND ITS DIFFERENTIATION FROM TYPICAL DOME-SHAPED MACULA IN ELDERLY MYOPIC PATIENTS.

Jan 24, 2020

To assess and compare clinical features of a ridge-shaped macula (defined as macular elevation only in one meridian across the fovea) in individuals younger than 20 years with those of a dome-shaped m...

Mild hypertension protects the elderly from cognitive impairment: a 7-year retrospective cohort study.

Jan 24, 2020

People with mild cognitive impairment have a high risk of converting to dementia. Previous studies have suggested that hypertension is implicated in the development of mild cognitive impairment, but s...

Multiple subcutaneous haematomas causing skin necrosis in elderly

Jan 24, 2020

Corticosteroid-induced skin atrophy (CISA) consists of a thinning of the skin and subcutaneous tissues, representing the natural consequence of a prolonged glucocorticosteroids use, both systemic as w...